Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer by Carlos S. Casimiro-Soriguer, Carlos Loucera, María Peña-Chilet, Joaquin Dopazo

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Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments by Cankut Çubuk, Fatma E. Can, María Peña-Chilet, Joaquín Dopazo

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The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery by Marina Esteban-Medina, Carlos Loucera, Kinza Rian, Sheyla Velasco, Lorena Olivares-González, Regina Rodrigo, Joaquin Dopazo, Maria Peña-Chilet

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A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways. by Martín Garrido-Rodriguez, Daniel Lopez-Lopez, Francisco M Ortuno, María Peña-Chilet, Eduardo Muñoz, Marco A Calzado, Joaquin Dopazo

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Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments by Carlos Loucera, Rosario Carmona, Marina Esteban-Medina, Gerrit Bostelmann, Dolores Muñoyerro-Muñiz, Román Villegas, María Peña-Chilet, Joaquín Dopazo

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drexml: A command line tool and Python package for drug repurposing by Marina Esteban-Medina, Víctor Manuel de la Oliva Roque, Sara Herráiz-Gil, María Peña-Chilet, Joaquín Dopazo, Carlos Loucera

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miRNA Expression Analysis: Cell Lines HCC1500 and HCC1937 as Models for Breast Cancer in Young Women and the miR-23a as a Poor Prognostic Biomarker by Sara S Oltra, Maria Peña-Chilet, Maria T Martinez, Eduardo Tormo, Juan Miguel Cejalvo, Joan Climent, Pilar Eroles, Ana Lluch, Gloria Ribas

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Breast Cancer in Very Young Patients in a Spanish Cohort: Age as an Independent Bad Prognostic Indicator by María Teresa Martínez, Sara S Oltra, María Peña-Chilet, Elisa Alonso, Cristina Hernando, Octavio Burgues, Isabel Chirivella, Begoña Bermejo, Ana Lluch, Gloria Ribas

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rs12512631 on the group specific complement (vitamin D-binding protein GC) implicated in melanoma susceptibility. by Maria Peña-Chilet, Maider Ibarrola-Villava, Manuel Martin-González, Marta Feito, Cristina Gomez-Fernandez, Dolores Planelles, Gregorio Carretero, Ana Lluch, Eduardo Nagore, Gloria Ribas

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Mechanistic modeling of the SARS-CoV-2 disease map by Kinza Rian, Marina Esteban-Medina, Marta R. Hidalgo, Cankut Çubuk, Matias M. Falco, Carlos Loucera, Devrim Gunyel, Marek Ostaszewski, María Peña-Chilet, Joaquín Dopazo

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An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in <i>rd10</i> Mice by Lorena Olivares-González, Sheyla Velasco, Idoia Gallego, Marina Esteban-Medina, Gustavo Puras, Carlos Loucera, Alicia Martínez-Romero, María Peña-Chilet, José Luis Pedraz, Regina Rodrigo

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Visualization of automatically combined disease maps and pathway diagrams for rare diseases by Piotr Gawron, David Hoksza, David Hoksza, Janet Piñero, Janet Piñero, Janet Piñero, Maria Peña-Chilet, Maria Peña-Chilet, Marina Esteban-Medina, Jose Luis Fernandez-Rueda, Vincenza Colonna, Vincenza Colonna, Ewa Smula, Laurent Heirendt, François Ancien, Valentin Groues, Venkata P. Satagopam, Reinhard Schneider, Joaquin Dopazo, Joaquin Dopazo, Laura I. Furlong, Laura I. Furlong, Laura I. Furlong, Marek Ostaszewski

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A Comprehensive Analysis of 21 Actionable Pharmacogenes in the Spanish Population: From Genetic Characterisation to Clinical Impact by Rocio Nunez-Torres, Guillermo Pita, María Peña-Chilet, Daniel López-López, Jorge Zamora, Gema Roldán, Belén Herráez, Nuria Álvarez, María Rosario Alonso, Joaquín Dopazo, Anna Gonzalez-Neira

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Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients by Carlos Loucera, María Peña-Chilet, Marina Esteban-Medina, Dolores Muñoyerro-Muñiz, Román Villegas, Jose Lopez-Miranda, Jesus Rodriguez-Baño, Isaac Túnez, Roger Bouillon, Joaquin Dopazo, Jose Manuel Quesada Gomez

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A crowdsourcing database for the copy-number variation of the Spanish population by Daniel López-López, Gema Roldán, Jose L. Fernández-Rueda, Gerrit Bostelmann, Rosario Carmona, Virginia Aquino, Javier Perez-Florido, Francisco Ortuño, Guillermo Pita, Rocío Núñez-Torres, Anna González-Neira, CSVS Crowdsourcing Group, María Peña-Chilet, Joaquin Dopazo

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A comprehensive database for integrated analysis of omics data in autoimmune diseases by Jordi Martorell-Marugán, Raúl López-Domínguez, Adrián García-Moreno, Daniel Toro-Domínguez, Juan Antonio Villatoro-García, Guillermo Barturen, Adoración Martín-Gómez, Kevin Troule, Gonzalo Gómez-López, Fátima Al-Shahrour, Víctor González-Rumayor, María Peña-Chilet, Joaquín Dopazo, Julio Sáez-Rodríguez, Marta E. Alarcón-Riquelme, Pedro Carmona-Sáez

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Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial by Andrés Redondo, Joaquin Dopazo, José A López-Martin, Nadia Hindi, Javier Martin-Broto, Silvia Stacchiotti, Giovanni Grignani, Claudia Valverde, Paola Collini, Javier Martinez-Trufero, Antonio Lopez-Pousa, Lorenzo D'Ambrosio, Antonio Gutierrez, Herminia Perez-Vega, Victor Encinas-Tobajas, Enrique de Alava, Maria Peña-Chilet, Irene Carrasco-Garcia, Maria Lopez-Alvarez, David S Moura

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Immune Cell Associations with Cancer Risk by Luis Palomero, Ivan Galván-Femenía, Rafael de Cid, Roderic Espín, Daniel R. Barnes, CIMBA, Eline Blommaert, Miguel Gil-Gil, Catalina Falo, Agostina Stradella, Dan Ouchi, Albert Roso-Llorach, Concepció Violan, María Peña-Chilet, Joaquín Dopazo, Ana Isabel Extremera, Mar García-Valero, Carmen Herranz, Francesca Mateo, Elisabetta Mereu, Jonathan Beesley, Georgia Chenevix-Trench, Cecilia Roux, Tak Mak, Joan Brunet, Razq Hakem, Chiara Gorrini, Antonis C. Antoniou, Conxi Lázaro, Miquel Angel Pujana

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A DNA damage repair gene‐associated signature predicts responses of patients with advanced soft‐tissue sarcoma to treatment with trabectedin by David S. Moura, Maria Peña‐Chilet, Juan Antonio Cordero Varela, Ramiro Alvarez‐Alegret, Carolina Agra‐Pujol, Francisco Izquierdo, Rafael Ramos, Luis Ortega‐Medina, Francisco Martin‐Davila, Carolina Castilla‐Ramirez, Carmen Nieves Hernandez‐Leon, Cleofe Romagosa, Maria Angeles Vaz Salgado, Javier Lavernia, Silvia Bagué, Empar Mayodormo‐Aranda, Luis Vicioso, Jose Emilio Hernández Barceló, Jordi Rubio‐Casadevall, Ana deJuan, Maria Concepcion Fiaño‐Valverde, Nadia Hindi, Maria Lopez‐Alvarez, Serena Lacerenza, Joaquin Dopazo, Antonio Gutierrez, Rosa Alvarez, Claudia Valverde, Javier Martinez‐Trufero, Javier Martín‐Broto

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Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches by Anna Niarakis, Anna Niarakis, Marek Ostaszewski, Alexander Mazein, Inna Kuperstein, Inna Kuperstein, Inna Kuperstein, Martina Kutmon, Marc E. Gillespie, Marc E. Gillespie, Akira Funahashi, Marcio Luis Acencio, Ahmed Hemedan, Michael Aichem, Karsten Klein, Tobias Czauderna, Felicia Burtscher, Takahiro G. Yamada, Yusuke Hiki, Noriko F. Hiroi, Noriko F. Hiroi, Finterly Hu, Finterly Hu, Nhung Pham, Nhung Pham, Friederike Ehrhart, Egon L. Willighagen, Alberto Valdeolivas, Aurelien Dugourd, Francesco Messina, Marina Esteban-Medina, Marina Esteban-Medina, Maria Peña-Chilet, Maria Peña-Chilet, Maria Peña-Chilet, Kinza Rian, Sylvain Soliman, Sara Sadat Aghamiri, Bhanwar Lal Puniya, Aurélien Naldi, Tomáš Helikar, Vidisha Singh, Marco Fariñas Fernández, Viviam Bermudez, Eirini Tsirvouli, Arnau Montagud, Vincent Noël, Vincent Noël, Vincent Noël, Miguel Ponce-de-Leon, Dieter Maier, Angela Bauch, Benjamin M. Gyori, John A. Bachman, Augustin Luna, Augustin Luna, Janet Piñero, Janet Piñero, Laura I. Furlong, Laura I. Furlong, Irina Balaur, Adrien Rougny, Adrien Rougny, Yohan Jarosz, Rupert W. Overall, Robert Phair, Livia Perfetto, Lisa Matthews, Devasahayam Arokia Balaya Rex, Marija Orlic-Milacic, Luis Cristobal Monraz Gomez, Luis Cristobal Monraz Gomez, Luis Cristobal Monraz Gomez, Bertrand De Meulder, Jean Marie Ravel, Jean Marie Ravel, Jean Marie Ravel, Bijay Jassal, Venkata Satagopam, Venkata Satagopam, Guanming Wu, Martin Golebiewski, Piotr Gawron, Laurence Calzone, Laurence Calzone, Laurence Calzone, Jacques S. Beckmann, Chris T. Evelo, Peter D’Eustachio, Falk Schreiber, Falk Schreiber, Julio Saez-Rodriguez, Joaquin Dopazo, Joaquin Dopazo, Joaquin Dopazo, Joaquin Dopazo, Martin Kuiper, Alfonso Valencia, Alfonso Valencia, Olaf Wolkenhauer, Olaf Wolkenhauer, Hiroaki Kitano, Emmanuel Barillot, Emmanuel Barillot, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID-19 Disease Map Community

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