MEMMAL: A tool for expanding large-scale mechanistic models with machine learned associations and big datasets by Cemal Erdem, Marc R. Birtwistle, Marc R. Birtwistle

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A Mechanistic Beta-Binomial Probability Model for mRNA Sequencing Data. by Gregory R Smith, Marc R Birtwistle

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A Comparison of Methods for RNA-Seq Differential Expression Analysis and a New Empirical Bayes Approach by Grzegorz A. Rempala, Marc R. Birtwistle, Sergiusz Wesolowski

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MOBILE pipeline enables identification of context-specific networks and regulatory mechanisms by Cemal Erdem, Sean M. Gross, Laura M. Heiser, Marc R. Birtwistle

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Network analyses of brain tumor multiomic data reveal pharmacological opportunities to alter cell state transitions by Brandon Bumbaca, Jonah R. Huggins, Marc R. Birtwistle, James M. Gallo

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Low-frequency ERK and Akt activity dynamics are predictive of stochastic cell division events by Jamie J. R. Bennett, Alan D. Stern, Xiang Zhang, Marc R. Birtwistle, Gaurav Pandey

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Evaluating strategies to normalise biological replicates of Western blot data. by Andrea Degasperi, Marc R Birtwistle, Natalia Volinsky, Jens Rauch, Walter Kolch, Boris N Kholodenko

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Predicting anti-cancer drug combination responses with a temporal cell state network model. by Deepraj Sarmah, Wesley O Meredith, Ian K Weber, Madison R Price, Marc R Birtwistle

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A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens. by Mehdi Bouhaddou, Anne Marie Barrette, Alan D Stern, Rick J Koch, Matthew S DiStefano, Eric A Riesel, Luis C Santos, Annie L Tan, Alex E Mertz, Marc R Birtwistle, Marc R Birtwistle

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Mitochondrial origins of fractional control in regulated cell death by Luís C. Santos, Robert Vogel, Jerry E. Chipuk, Marc R. Birtwistle, Gustavo Stolovitzky, Pablo Meyer

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Network inference from perturbation time course data by Deepraj Sarmah, Gregory R. Smith, Mehdi Bouhaddou, Alan D. Stern, James Erskine, Marc R. Birtwistle

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Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses by Marc R Birtwistle, Mariko Hatakeyama, Noriko Yumoto, Babatunde A Ogunnaike, Jan B Hoek, Boris N Kholodenko

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Novel somatic mutations to PI3K pathway genes in metastatic melanoma. by Austin Y Shull, Alicia Latham-Schwark, Poornema Ramasamy, Kristin Leskoske, Dora Oroian, Marc R Birtwistle, Phillip J Buckhaults

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Mechanistic Systems Modeling to Improve Understanding and Prediction of Cardiotoxicity Caused by Targeted Cancer Therapeutics by Jaehee V. Shim, Bryan Chun, Johan G. C. van Hasselt, Marc R. Birtwistle, Jeffrey J. Saucerman, Eric A. Sobie

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Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer by Mehdi Bouhaddou, Li J. Yu, Serena Lunardi, Spyros K. Stamatelos, Fiona Mack, James M. Gallo, Marc R. Birtwistle, Antje‐Christine Walz

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Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array by Rick J. Koch, Anne Marie Barrette, Alan D. Stern, Bin Hu, Mehdi Bouhaddou, Evren U. Azeloglu, Ravi Iyengar, Marc R. Birtwistle

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Relating individual cell division events to single-cell ERK and Akt activity time courses by Alan D. Stern, Gregory R. Smith, Luis C. Santos, Deepraj Sarmah, Xiang Zhang, Xiaoming Lu, Federico Iuricich, Gaurav Pandey, Ravi Iyengar, Marc R. Birtwistle

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A scalable, open-source implementation of a large-scale mechanistic model for single cell proliferation and death signaling by Cemal Erdem, Arnab Mutsuddy, Ethan M. Bensman, William B. Dodd, Michael M. Saint-Antoine, Mehdi Bouhaddou, Robert C. Blake, Sean M. Gross, Laura M. Heiser, F. Alex Feltus, Marc R. Birtwistle

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Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity by Yuguang Xiong, Tong Liu, Tong Chen, Jens Hansen, Bin Hu, Yibang Chen, Gomathi Jayaraman, Stephan Schürer, Dusica Vidovic, Joseph Goldfarb, Eric A. Sobie, Marc R. Birtwistle, Ravi Iyengar, Hong Li, Evren U. Azeloglu

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Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity by J. G. Coen van Hasselt, Rayees Rahman, Jens Hansen, Alan Stern, Jaehee V. Shim, Yuguang Xiong, Amanda Pickard, Gomathi Jayaraman, Bin Hu, Milind Mahajan, James M. Gallo, Joseph Goldfarb, Eric A. Sobie, Marc R. Birtwistle, Avner Schlessinger, Evren U. Azeloglu, Ravi Iyengar

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