Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemCellFactory by Bastian Nießing, Yannik Breitkreuz, Yannik Breitkreuz, Andreas Elanzew, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Peter Vajs, Marina Nolden, Frederik Erkens, Paul Wanek, Paul Wanek, Si Wah Christina Au Yeung, Simone Haupt, Niels König, Michael Peitz, Michael Peitz, Michael Peitz, Robert H. Schmitt, Robert H. Schmitt, Martin Zenke, Martin Zenke, Martin Zenke, Martin Zenke, Oliver Brüstle, Oliver Brüstle

Get full text

P1365: HUMAN CD117 AS AN IMMUNOTHERAPEUTIC TARGET IN PRECLINICAL MODELS OF ADVANCED SYSTEMIC MASTOCYTOSIS by Anne Kaiser, Renier Myburgh, Laura Volta, Christian Pellegrino, Veronika Lysenko, Alexandre Theocharides, Tim H Brümmendorf, Marcelo A.S. de Toledo, Martin Zenke, Markus Manz

Get full text

The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling by Kathrin Olschok, Kathrin Olschok, Bianca Altenburg, Bianca Altenburg, Marcelo A. S. de Toledo, Marcelo A. S. de Toledo, Angela Maurer, Angela Maurer, Anne Abels, Anne Abels, Fabian Beier, Fabian Beier, Deniz Gezer, Deniz Gezer, Susanne Isfort, Susanne Isfort, Katrin Paeschke, Katrin Paeschke, Tim H. Brümmendorf, Tim H. Brümmendorf, Martin Zenke, Martin Zenke, Nicolas Chatain, Nicolas Chatain, Steffen Koschmieder, Steffen Koschmieder

Get full text

P1008: THE TELOMERASE INHIBITOR IMETELSTAT DIFFERENTIALLY TARGETS JAK2V617F- VERSUS CALR-MUTANT MYELOPROLIFERATIVE NEOPLASM CELLS AND INHIBITS JAK-STAT SIGNALING by Kathrin Olschok, Bianca Altenburg, Marcelo A.S. de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder

Get full text

Generation of a TMEM43 knockout human induced pluripotent stem cell line (HDZi003-A-1) using CRISPR/Cas9 by Sandra Ratnavadivel, Joline Dammeier, Anna Gaertner, Marcelo A. Szymanski de Toledo, Martin Zenke, Jan Gummert, Torsten Bloch Rasmussen, Nora Klinke, Kai Jürgens, Heiko Meyer, Achim Paululat, Hendrik Milting

Get full text

Cellular aging is accelerated in the malignant clone of myeloproliferative neoplasms by Margherita Vieri, Vithurithra Tharmapalan, Milena Kalmer, Julian Baumeister, Miloš Nikolić, Matthis Schnitker, Martin Kirschner, Niclas Flosdorf, Marcelo A. S. de Toledo, Martin Zenke, Steffen Koschmieder, Tim H. Brümmendorf, Fabian Beier, Wolfgang Wagner

Get full text