The effects of age and systemic metabolism on anti-tumor T cell responses by Jefte M Drijvers, Arlene H Sharpe, Marcia C Haigis

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An LC-MS Approach to Quantitative Measurement of Ammonia Isotopologues by Jessica B. Spinelli, Liam P. Kelley, Marcia C. Haigis

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Metabolic analyses reveal dysregulated NAD+ metabolism and altered mitochondrial state in ulcerative colitis. by Yu Hui Kang, Sarah A Tucker, Silvia F Quevedo, Aslihan Inal, Joshua R Korzenik, Marcia C Haigis

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Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. by Lydia W S Finley, Wilhelm Haas, Valérie Desquiret-Dumas, Douglas C Wallace, Vincent Procaccio, Steven P Gygi, Marcia C Haigis

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T Cell Activation Depends on Extracellular Alanine by Noga Ron-Harel, Jonathan M. Ghergurovich, Giulia Notarangelo, Martin W. LaFleur, Yoshiki Tsubosaka, Arlene H. Sharpe, Joshua D. Rabinowitz, Marcia C. Haigis

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SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis by Sarah A. Tucker, Song-Hua Hu, Sejal Vyas, Albert Park, Shakchhi Joshi, Aslihan Inal, Tiffany Lam, Emily Tan, Kevin M. Haigis, Marcia C. Haigis

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Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers. by Sylwia A Stopka, Jiska van der Reest, Walid M Abdelmoula, Daniela F Ruiz, Shakchhi Joshi, Alison E Ringel, Marcia C Haigis, Nathalie Y R Agar

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Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome by Mengmeng Huang, Alexander A. Akerberg, Xiaoran Zhang, Haejin Yoon, Shakchhi Joshi, Celia Hallinan, Christopher Nguyen, William T. Pu, Marcia C. Haigis, C. Geoffrey Burns, Caroline E. Burns

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l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism by Yusuke Adachi, Ana Luisa De Sousa-Coelho, Ikue Harata, Charlie Aoun, Sandra Weimer, Xu Shi, Karina N. Gonzalez Herrera, Hirokazu Takahashi, Chris Doherty, Yasushi Noguchi, Laurie J. Goodyear, Marcia C. Haigis, Robert E. Gerszten, Mary-Elizabeth Patti

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SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis by Elma Zaganjor, Haejin Yoon, Jessica B. Spinelli, Elizabeth R. Nunn, Gaëlle Laurent, Paulina Keskinidis, Suganja Sivaloganathan, Shakchhi Joshi, Giulia Notarangelo, Stacy Mulei, Mathew T. Chvasta, Sarah A. Tucker, Krystle Kalafut, Robert A.H. van de Ven, Clary B. Clish, Marcia C. Haigis

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Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3 by Karina N. Gonzalez Herrera, Elma Zaganjor, Yoshinori Ishikawa, Jessica B. Spinelli, Haejin Yoon, Jia-Ren Lin, F. Kyle Satterstrom, Alison Ringel, Stacy Mulei, Amanda Souza, Joshua M. Gorham, Craig C. Benson, Jonathan G. Seidman, Peter K. Sorger, Clary B. Clish, Marcia C. Haigis

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Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia by Barry M. Zee, Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy, William D. Jacobus, Elizabeth Senior, Jennifer E. Endress, Ashwini Jambhekar, Scott B. Lovitch, Jiexian Ma, Abhinav Dhall, Isaac S. Harris, M. Andres Blanco, David B. Sykes, Jonathan D. Licht, David M. Weinstock, Ari Melnick, Marcia C. Haigis, Franziska Michor, Yang Shi

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