Tau protein modulates an epigenetic mechanism of cellular senescence in human SH-SY5Y neuroblastoma cells by Claudia Magrin, Claudia Magrin, Martina Bellafante, Martina Sola, Martina Sola, Ester Piovesana, Ester Piovesana, Marco Bolis, Marco Bolis, Marco Bolis, Luciano Cascione, Luciano Cascione, Sara Napoli, Andrea Rinaldi, Stéphanie Papin, Paolo Paganetti, Paolo Paganetti

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Protocol for interpretable and context-specific single-cell-informed deconvolution of bulk RNA-seq data by Daniele Malpetti, Francesca Mangili, Marco Bolis, Anna Rinaldi, David Legouis, Lorenzo Ruinelli, Pietro Cippà, Laura Azzimonti

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Cancer-specific association between Tau (MAPT) and cellular pathways, clinical outcome, and drug response by Maurizio Callari, Martina Sola, Claudia Magrin, Andrea Rinaldi, Marco Bolis, Paolo Paganetti, Luca Colnaghi, Stéphanie Papin

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Human gut epithelium features recapitulated in MINERVA 2.0 millifluidic organ-on-a-chip device by Francesca Donnaloja, Luca Izzo, Marzia Campanile, Simone Perottoni, Lucia Boeri, Francesca Fanizza, Lorenzo Sardelli, Emanuela Jacchetti, Manuela T. Raimondi, Laura Di Rito, Ilaria Craparotta, Marco Bolis, Carmen Giordano, Diego Albani

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Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer by Martina Troiani, Manuel Colucci, Mariantonietta D’Ambrosio, Ilaria Guccini, Emiliano Pasquini, Angelica Varesi, Aurora Valdata, Simone Mosole, Ajinkya Revandkar, Giuseppe Attanasio, Andrea Rinaldi, Anna Rinaldi, Marco Bolis, Pietro Cippà, Andrea Alimonti

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Author Correction: Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer by Martina Troiani, Manuel Colucci, Mariantonietta D’Ambrosio, Ilaria Guccini, Emiliano Pasquini, Angelica Varesi, Aurora Valdata, Simone Mosole, Ajinkya Revandkar, Giuseppe Attanasio, Andrea Rinaldi, Anna Rinaldi, Marco Bolis, Pietro Cippà, Andrea Alimonti

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A transfer learning framework to elucidate the clinical relevance of altered proximal tubule cell states in kidney disease by David Legouis, Anna Rinaldi, Daniele Malpetti, Gregoire Arnoux, Thomas Verissimo, Anna Faivre, Francesca Mangili, Andrea Rinaldi, Lorenzo Ruinelli, Jerome Pugin, Solange Moll, Luca Clivio, Marco Bolis, Sophie de Seigneux, Laura Azzimonti, Pietro E. Cippà

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Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development by Ilaria Guccini, Guanghui Tang, Trang Thuy To, Laura Di Rito, Solange Le Blanc, Oliver Strobel, Mariantonietta D’Ambrosio, Emiliano Pasquini, Marco Bolis, Pamuditha Silva, Hasan Ali Kabakci, Svenja Godbersen, Andrea Alimonti, Gerald Schwank, Markus Stoffel

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Anti-tumor activity of all-trans retinoic acid in gastric-cancer: gene-networks and molecular mechanisms by Luca Guarrera, Mami Kurosaki, Silvio-Ken Garattini, Maurizio Gianni’, Gianpiero Fasola, Luca Rossit, Michele Prisciandaro, Maria Di Bartolomeo, Marco Bolis, Paola Rizzo, Claudia Nastasi, Marika Foglia, Adriana Zanetti, Gabriela Paroni, Mineko Terao, Enrico Garattini

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Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer by Alessia Cacciatore, Dheeraj Shinde, Carola Musumeci, Giada Sandrini, Luca Guarrera, Domenico Albino, Gianluca Civenni, Elisa Storelli, Simone Mosole, Elisa Federici, Alessio Fusina, Marta Iozzo, Andrea Rinaldi, Matteo Pecoraro, Roger Geiger, Marco Bolis, Carlo V. Catapano, Giuseppina M. Carbone

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Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma by Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrochi, Roberto Piva, Antonino Neri

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Cellular and molecular determinants of all‐trans retinoic acid sensitivity in breast cancer: Luminal phenotype and RARα expression by Floriana Centritto, Gabriela Paroni, Marco Bolis, Silvio Ken Garattini, Mami Kurosaki, Maria Monica Barzago, Adriana Zanetti, James Neil Fisher, Mark Francis Scott, Linda Pattini, Monica Lupi, Paolo Ubezio, Francesca Piccotti, Alberto Zambelli, Paola Rizzo, Maurizio Gianni', Maddalena Fratelli, Mineko Terao, Enrico Garattini

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Onvansertib treatment overcomes olaparib resistance in high-grade ovarian carcinomas by Michela Chiappa, Alessandra Decio, Luca Guarrera, Ilaria Mengoli, Anju Karki, Divora Yemane, Carmen Ghilardi, Eugenio Scanziani, Simone Canesi, Maria C. Barbera, Ilaria Craparotta, Marco Bolis, Robert Fruscio, Chiara Grasselli, Tommaso Ceruti, Massimo Zucchetti, Jesse C. Patterson, Robin A. Lu, Micheal B. Yaffe, Maya Ridinger, Giovanna Damia, Federica Guffanti

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Increased ectodysplasin-A2-receptor EDA2R is a ubiquitous hallmark of aging and mediates parainflammatory responses by Maria Chiara Barbera, Luca Guarrera, Andrea David Re Cecconi, Giada Andrea Cassanmagnago, Arianna Vallerga, Martina Lunardi, Francesca Checchi, Laura Di Rito, Margherita Romeo, Sarah Natalia Mapelli, Benedikt Schoser, Edward V. Generozov, Molecular Genetics Group, Rick Jansen, Eco J. C. de Geus, Brenda Penninx, Jenny van Dongen, Ilaria Craparotta, Rosanna Piccirillo, Ildus I. Ahmetov, Marco Bolis

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Small molecule-mediated inhibition of the oxidoreductase ERO1A restrains aggressive breast cancer by impairing VEGF and PD-L1 in the tumor microenvironment by Ersilia Varone, Michele Retini, Alessandro Cherubini, Alexander Chernorudskiy, Alice Marrazza, Andrea Guidarelli, Alfredo Cagnotto, Marten Beeg, Marco Gobbi, Stefano Fumagalli, Marco Bolis, Luca Guarrera, Maria Chiara Barbera, Chiara Grasselli, Augusto Bleve, Daniele Generali, Manuela Milani, Michele Mari, Mario Salmona, Giovanni Piersanti, Giovanni Bottegoni, Massimo Broggini, Yvonne M. W. Janssen-Heininger, Jaehyung Cho, Orazio Cantoni, Ester Zito

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STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer by Monika Oberhuber, Matteo Pecoraro, Mate Rusz, Georg Oberhuber, Maritta Wieselberg, Peter Haslinger, Elisabeth Gurnhofer, Michaela Schlederer, Tanja Limberger, Sabine Lagger, Jan Pencik, Petra Kodajova, Sandra Högler, Georg Stockmaier, Sandra Grund‐Gröschke, Fritz Aberger, Marco Bolis, Jean‐Philippe Theurillat, Robert Wiebringhaus, Theresa Weiss, Andrea Haitel, Marc Brehme, Wolfgang Wadsak, Johannes Griss, Thomas Mohr, Alexandra Hofer, Anton Jäger, Jürgen Pollheimer, Gerda Egger, Gunda Koellensperger, Matthias Mann, Brigitte Hantusch, Lukas Kenner

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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression by Torben Redmer, Martin Raigel, Christina Sternberg, Roman Ziegler, Clara Probst, Desiree Lindner, Astrid Aufinger, Tanja Limberger, Karolina Trachtova, Petra Kodajova, Sandra Högler, Michaela Schlederer, Stefan Stoiber, Monika Oberhuber, Marco Bolis, Heidi A. Neubauer, Sara Miranda, Martina Tomberger, Nora S. Harbusch, Ines Garces de los Fayos Alonso, Felix Sternberg, Richard Moriggl, Jean-Philippe Theurillat, Boris Tichy, Vojtech Bystry, Jenny L. Persson, Stephan Mathas, Fritz Aberger, Birgit Strobl, Sarka Pospisilova, Olaf Merkel, Gerda Egger, Sabine Lagger, Lukas Kenner

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