The microglial immunoreceptor tyrosine‐based motif‐Syk signaling pathway is a promising target of immunotherapy for Alzheimer's disease by Shoutang Wang, Marco Colonna

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Mechanisms and environmental factors shaping the ecosystem of brain macrophages by Silvia Penati, Simone Brioschi, Zhangying Cai, Claudia Z. Han, Claudia Z. Han, Marco Colonna, Marco Colonna

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Reviewing the <i>Clostridioides difficile</i> Mouse Model: Insights into Infection Mechanisms by José L. Fachi, Marco A. R. Vinolo, Marco Colonna

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TREM2 dependent and independent functions of microglia in Alzheimer’s disease by Jinchao Hou, Yun Chen, Gary Grajales-Reyes, Marco Colonna

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Lung type 3 innate lymphoid cells respond early following Mycobacterium tuberculosis infection by Shibali Das, Kuldeep Singh Chauhan, Mushtaq Ahmed, Sadia Akter, Lan Lu, Marco Colonna, Shabaana A. Khader

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TREM2 promotes lung fibrosis via controlling alveolar macrophage survival and pro-fibrotic activity by Huachun Cui, Sami Banerjee, Na Xie, Musaddique Hussain, Ashish Jaiswal, Hongli Liu, Tejaswini Kulkarni, Veena B. Antony, Rui-Ming Liu, Marco Colonna, Gang Liu

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TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells by Alessandra Tammaro, Angelique M. L. Scantlebery, Elena Rampanelli, Cristiana Borrelli, Cristiana Borrelli, Nike Claessen, Loes M. Butter, Alessandra Soriani, Marco Colonna, Jaklien C. Leemans, Mark C. Dessing, Sandrine Florquin

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High‐affinity interactions and signal transduction between Aβ oligomers and TREM2 by Christian B Lessard, Samuel L Malnik, Yingyue Zhou, Thomas B Ladd, Pedro E Cruz, Yong Ran, Thomas E Mahan, Paramita Chakrabaty, David M Holtzman, Jason D Ulrich, Marco Colonna, Todd E Golde

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Species- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air–liquid interface respiratory epithelial cultures by Mian Horvath, Ruoyu Yang, Diana Cadena Castaneda, Megan Callender, Elizabeth S. Aiken, Anita Y. Voigt, Ryan Caldwell, José Fachi, Blanda Di Luccia, Zoe Scholar, Peter Yu, Andrew Salner, Marco Colonna, Karolina Palucka, Julia Oh

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Nuclear receptor ligands induce TREM-1 expression on dendritic cells: analysis of their role in tumors by Raffaella Fontana, Laura Raccosta, Lucrezia Rovati, Knut R. Steffensen, Aida Paniccia, Tomas Jakobsson, Giulio Melloni, Alessandro Bandiera, Giorgia Mangili, Alice Bergamini, Daniela Maggioni, Claudio Doglioni, Roberto Crocchiolo, Marina Cella, Michela Mattioli, Cristina Battaglia, Marco Colonna, Vincenzo Russo

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Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling by Rafaela M Guimarães, Conceição E Aníbal-Silva, Marcela Davoli-Ferreira, Francisco Isaac F Gomes, Atlante Mendes, Maria CM Cavallini, Miriam M Fonseca, Samara Damasceno, Larissa P Andrade, Marco Colonna, Cyril Rivat, Fernando Q Cunha, José C Alves-Filho, Thiago M Cunha

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IL‐34 deficiency impairs FOXP3+ Treg function in a model of autoimmune colitis and decreases immune tolerance homeostasis by Antoine Freuchet, Apolline Salama, Séverine Bézie, Laurent Tesson, Séverine Rémy, Romain Humeau, Hadrien Règue, Céline Sérazin, Léa Flippe, Pärt Peterson, Nadège Vimond, Claire Usal, Séverine Ménoret, Jean‐Marie Heslan, Franck Duteille, Frédéric Blanchard, Magali Giral, Marco Colonna, Ignacio Anegon, Carole Guillonneau

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Comparing neoantigen cancer vaccines and immune checkpoint therapy unveils an effective vaccine and anti-TREM2 macrophage-targeting dual therapy by Sunita Keshari, Alexander S. Shavkunov, Qi Miao, Akata Saha, Tomoyuki Minowa, Martina Molgora, Charmelle D. Williams, Mehdi Chaib, Anna M. Highsmith, Josué E. Pineda, Sayan Alekseev, Elise Alspach, Kenneth H. Hu, Marco Colonna, Kristen E. Pauken, Ken Chen, Matthew M. Gubin

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1006 High doses of MHC-II neoantigens in peptide cancer vaccines induce tumor-specific inhibitory cytolytic CD4+ T cells by Naveen Sharma, James Allison, Andres Salazar, Hussein Sultan, Ton Schumacher, Ivana Djuretic, Yik Andy Yeung, Jeffrey Ward, Marco Colonna, Yuang Song, Samuel Ameh, Robert Schreiber, Kenneth Murphy, Yoshiko Takeuchi, Corazon Arthur, Kathleen Sheehan, Kelly D Moynihan, Vladimir Sukhov, Maria Firulyova, Tian-Tian Liu, Maxim Artyomov

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination by Jinchao Hou, Yingyue Zhou, Zhangying Cai, Marina Terekhova, Amanda Swain, Prabhakar S. Andhey, Rafaela M. Guimaraes, Alina Ulezko Antonova, Tian Qiu, Sanja Sviben, Gregory Strout, James A.J. Fitzpatrick, Yun Chen, Susan Gilfillan, Do-Hyun Kim, Steven J. Van Dyken, Maxim N. Artyomov, Marco Colonna

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Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3 by José L. Fachi, Laís. P. Pral, Helder C. Assis, Sarah Oliveira, Vinícius R. Rodovalho, Jefferson A. C. dos Santos, Mariane F. Fernandes, Valquíria A. Matheus, Renata Sesti-Costa, Paulo J. Basso, Marina Flóro e Silva, Niels O. S. Câmara, Selma Giorgio, Marco Colonna, Marco A. R. Vinolo

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Tissue-resident CCR2+ macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts by Yuriko Terada, Wenjun Li, Junedh M. Amrute, Amit I. Bery, Charles R. Liu, Venkatrao Nunna, Christian Corbin Frye, Hao Dun, Andrew L. Koenig, Hannah P. Luehmann, Gyu Seong Heo, Macee C. Owen, Alexander N. Wein, Yongjian Liu, Jon H. Ritter, Sumanth D. Prabhu, Ruben G. Nava, Andrew E. Gelman, Marina Cella, Marco Colonna, Kory J. Lavine, Daniel Kreisel

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Correction: Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium by Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El‑Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga‑Weisz, Marco Aurélio Ramirez Vinolo

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Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium by Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El-Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga-Weisz, Marco Aurélio Ramirez Vinolo

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