762 A combination of functional biomarkers improves identification of the tumor-specific reactive T cell repertoire by Marco Donia, Arianna Draghi, Katja Harbst, Inge Svane

36 Degradation of type III and IV collagen associates with outcome when measured in serum from patients with metastatic melanoma treated with immune checkpoint inhibitors by Marco Donia, Christina Jensen, Nicholas Willumsen, Inge Svane, Anders Kverneland, Morten A Karsdal

Intratumoral T-cell and B-cell receptor architecture associates with distinct immune tumor microenvironment features and clinical outcomes of anti-PD-1/L1 immunotherapy by Marco Donia, Göran Jönsson, Inge Marie Svane, Aimilia Schina, Zsofia Sztupinszki, Zoltan Szallasi

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Genetic Biomarkers in Melanoma of the Ocular Region: What the Medical Oncologist Should Know by Kalijn Fredrike Bol, Marco Donia, Steffen Heegaard, Jens Folke Kiilgaard, Inge Marie Svane

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822 IL6R-blockade abolishes the anti-tumor effect of TGFβ-derived immune modulatory vaccination in a murine model of pancreatic cancer by Marco Donia, Mads Andersen, Shawez Khan, Maria Perez Penco, Lucia Lara de la Torre

Improved Progression-Free Long-Term Survival of a Nation-Wide Patient Population with Metastatic Melanoma by Anne Vest Soerensen, Eva Ellebaek, Lars Bastholt, Henrik Schmidt, Marco Donia, Inge Marie Svane

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Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab by Anders H. Kverneland, Christian Enevold, Marco Donia, Lars Bastholt, Inge Marie Svane, Claus H. Nielsen

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Highly efficient PD-1-targeted CRISPR-Cas9 for tumor-infiltrating lymphocyte-based adoptive T cell therapy by Christopher Aled Chamberlain, Eric Paul Bennett, Anders Handrup Kverneland, Inge Marie Svane, Marco Donia, Özcan Met

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Biomarkers for response to TIL therapy: a comprehensive review by Marco Donia, Troels Holz Borch, Inge Marie Svane, Víctor Albarrán Fernández, Pablo Ballestín Martínez, Joachim Stoltenborg Granhøj

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Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression by Eszter Molnár, Tamás Garay, Marco Donia, Marcell Baranyi, Dominika Rittler, Walter Berger, József Tímár, Michael Grusch, Balázs Hegedűs

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Prospective Assessment of Fluorine-18-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography (FDG-PET/CT) for Early Identification of Checkpoint-Inhibitor-Induced Pseu... by Sif Homburg, Charlotte Birk Christensen, Magnus Pedersen, Simon Grund Sørensen, Marco Donia, Inge Marie Svane, Helle Westergren Hendel, Eva Ellebaek

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1030 Peripheral immunological dynamics of response in pancreatic cancer treated with immune checkpoint inhibitors by Marco Donia, Inge Marie Svane, Arianna Draghi, Inna M Chen, Shawez Khan, Mario Presti, Christopher A Chamberlain, Marta Sanchez Sanchez

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma by Martin Lauss, Marco Donia, Katja Harbst, Rikke Andersen, Shamik Mitra, Frida Rosengren, Maryem Salim, Johan Vallon-Christersson, Therese Törngren, Anders Kvist, Markus Ringnér, Inge Marie Svane, Göran Jönsson

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Author Correction: Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma by Martin Lauss, Marco Donia, Katja Harbst, Rikke Andersen, Shamik Mitra, Frida Rosengren, Maryem Salim, Johan Vallon-Christersson, Therese Törngren, Anders Kvist, Markus Ringnér, Inge Marie Svane, Göran Jönsson

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Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma by Kalijn Fredrike Bol, Eva Ellebaek, Lise Hoejberg, Mette Marie Bagger, Mathilde Skaarup Larsen, Tobias Wirenfeldt Klausen, Ulrich Heide Køhler, Henrik Schmidt, Lars Bastholt, Jens Folke Kiilgaard, Marco Donia, Inge Marie Svane

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The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy by Shamaila Munir Ahmad, Evelina Martinenaite, Morten Holmström, Mia Aaboe Jørgensen, Özcan Met, Claudia Nastasi, Uffe Klausen, Marco Donia, Lars Møller Pedersen, Lars Munksgaard, Niels Ødum, Anders Woetmann, Inge Marie Svane, Mads Hald Andersen

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Chitooligosaccharides Improve the Efficacy of Checkpoint Inhibitors in a Mouse Model of Lung Cancer by Astrid Zedlitz Johansen, Marco Carretta, Marie-Louise Thorseth, Shawez Khan, Klaire Yixin Fjæstad, Christian Beltoft Brøchner, Hannes Linder, Christina Ankjærgaard, Marco Donia, Inna Chen, Dorte Lisbet Nielsen, Claus Preibisch Behrens, Daniel Hargbøl Madsen

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Ex vivo modulation of intact tumor fragments with anti-PD-1 and anti-CTLA-4 influences the expansion and specificity of tumor-infiltrating lymphocytes by Thomas Morgan Hulen, Christina Friese, Nikolaj Pagh Kristensen, Joachim Stoltenborg Granhøj, Troels Holz Borch, Marlies J. W. Peeters, Marco Donia, Mads Hald Andersen, Sine Reker Hadrup, Inge Marie Svane, Özcan Met, Özcan Met

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Molecular patterns of resistance to immune checkpoint blockade in melanoma by Martin Lauss, Bengt Phung, Troels Holz Borch, Katja Harbst, Kamila Kaminska, Anna Ebbesson, Ingrid Hedenfalk, Joan Yuan, Kari Nielsen, Christian Ingvar, Ana Carneiro, Karolin Isaksson, Kristian Pietras, Inge Marie Svane, Marco Donia, Göran Jönsson

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Comparison of Efficacy in Patients with Metastatic Melanoma Treated with Ipilimumab and Nivolumab Who Did or Did Not Discontinue Treatment Due to Immune-Related Adverse Events: A R... by Morten Fink, Anders Schwartz Vittrup, Lars Bastholt, Inge Marie Svane, Marco Donia, Adam A. Luczak, Christina H. Ruhlmann, Louise Mahncke Guldbrandt, Ulrich Heide Koehler, Mette Lerche Winther, Eva Ellebaek, Charlotte Aaquist Haslund, Henrik Schmidt

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