Different roles for the acyl chain and the amine leaving group in the substrate selectivity of N-Acylethanolamine acid amidase by Andrea Ghidini, Laura Scalvini, Francesca Palese, Alessio Lodola, Marco Mor, Daniele Piomelli

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A catalytic mechanism for cysteine N-terminal nucleophile hydrolases, as revealed by free energy simulations. by Alessio Lodola, Davide Branduardi, Marco De Vivo, Luigi Capoferri, Marco Mor, Daniele Piomelli, Andrea Cavalli

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Comparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists by Donatella Callegari, Daniele Pala, Laura Scalvini, Massimiliano Tognolini, Matteo Incerti, Silvia Rivara, Marco Mor, Alessio Lodola

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MT2 selective melatonin receptor antagonists: design and structure-activity relationships by Silvia Rivara, Marco Mor, Simone Lorenzi, Alessio Lodola, Pier Vincenzo Plazzi Gilberto Spadoni, Annalida Bedini, Giorgio Tarzia

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COMBINED TARGETING OF FATTY ACID AMIDE HYDROLASE AND MELATONIN RECEPTORS PROMOTES NEUROPROTECTION AND STIMULATES INFLAMMATION RESOLUTION IN RATS by Mariarosaria Cammarota, Francesca Ferlenghi, Federica Vacondio, Fabrizio Vincenzi, Katia Varani, Annalida Bedini, Silvia Rivara, Marco Mor, Francesca Boscia

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Metabolic Soft Spot and Pharmacokinetics: Functionalization of C-3 Position of an Eph–Ephrin Antagonist Featuring a Bile Acid Core as an Effective Strategy to Obtain Oral Bioavaila... by Francesca Ferlenghi, Carmine Giorgio, Matteo Incerti, Lorenzo Guidetti, Paola Chiodelli, Marco Rusnati, Massimiliano Tognolini, Federica Vacondio, Marco Mor, Alessio Lodola

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Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria by Gian Marco Elisi, Annalida Bedini, Laura Scalvini, Caterina Carmi, Silvia Bartolucci, Valeria Lucini, Francesco Scaglione, Marco Mor, Silvia Rivara, Gilberto Spadoni

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The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach by Sara Rezzola, Roberto Ronca, Alessandra Loda, Mohd Imtiaz Nawaz, Chiara Tobia, Giuseppe Paganini, Federica Maccarinelli, Arianna Giacomini, Francesco Semeraro, Marco Mor, Marco Presta

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Repurposing of Drugs Targeting YAP-TEAD Functions by Gian Marco Elisi, Matteo Santucci, Domenico D’Arca, Angela Lauriola, Gaetano Marverti, Lorena Losi, Laura Scalvini, Maria Laura Bolognesi, Marco Mor, Maria Paola Costi

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Amino Acid Derivatives as Palmitoylethanolamide Prodrugs: Synthesis, In Vitro Metabolism and In Vivo Plasma Profile in Rats. by Federica Vacondio, Michele Bassi, Claudia Silva, Riccardo Castelli, Caterina Carmi, Laura Scalvini, Alessio Lodola, Valentina Vivo, Lisa Flammini, Elisabetta Barocelli, Marco Mor, Silvia Rivara

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Molecular Mechanisms Underlying the Antitumor Activity of 3-Aminopropanamide Irreversible Inhibitors of the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer by Elena Galvani, Elisa Giovannetti, Francesca Saccani, Andrea Cavazzoni, Leticia G. Leon, Henk Dekker, Roberta Alfieri, Caterina Carmi, Marco Mor, Andrea Ardizzoni, Pier Giorgio Petronini, Godefridus J. Peters

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NAAA-regulated lipid signaling in monocytes controls the induction of hyperalgesic priming in mice by Yannick Fotio, Alex Mabou Tagne, Erica Squire, Hye-lim Lee, Connor M. Phillips, Kayla Chang, Faizy Ahmed, Andrew S. Greenberg, S. Armando Villalta, Vanessa M. Scarfone, Gilberto Spadoni, Marco Mor, Daniele Piomelli

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Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor by Alessio Lodola, Silvia Rivara, Elisabetta Barocelli, Francesca De Franco, Paola Vicini, Antimo Gioiello, Carmine Giorgio, Iftiin Hassan-Mohamed, Riccardo Castelli, Daniele Pala, Matteo Incerti, Marco Mor, Massimiliano Tognolini, Simonetta Russo

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Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-<i>b</i>]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affin... by Claudia Mugnaini, Magdalena Kostrzewa, Marta Casini, Poulami Kumar, Valeria Catallo, Marco Allarà, Laura Guastaferro, Antonella Brizzi, Marco Paolino, Andrea Tafi, Christelos Kapatais, Gianluca Giorgi, Federica Vacondio, Marco Mor, Federico Corelli, Alessia Ligresti

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Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library by Angela Lauriola, Elisa Uliassi, Matteo Santucci, Maria Laura Bolognesi, Marco Mor, Laura Scalvini, Gian Marco Elisi, Gaia Gozzi, Lorenzo Tagliazucchi, Gaetano Marverti, Stefania Ferrari, Lorena Losi, Domenico D’Arca, Maria Paola Costi

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Expanding the Arsenal of FGFR Inhibitors: A Novel Chloroacetamide Derivative as a New Irreversible Agent With Anti-proliferative Activity Against FGFR1-Amplified Lung Cancer Cell L... by Claudia Fumarola, Nicole Bozza, Riccardo Castelli, Francesca Ferlenghi, Giuseppe Marseglia, Alessio Lodola, Mara Bonelli, Silvia La Monica, Daniele Cretella, Roberta Alfieri, Roberta Minari, Maricla Galetti, Maricla Galetti, Marcello Tiseo, Marcello Tiseo, Andrea Ardizzoni, Marco Mor, Pier Giorgio Petronini

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Disentangling the interactions between nasopharyngeal and gut microbiome and their involvement in the modulation of COVID-19 infection by Leonardo Mancabelli, Giuseppe Taurino, Andrea Ticinesi, Tecla Ciociola, Federica Vacondio, Christian Milani, Federico Fontana, Gabriele Andrea Lugli, Chiara Tarracchini, Giulia Alessandri, Alice Viappiani, Massimiliano Bianchi, Antonio Nouvenne, Alfredo Antonio Chetta, Francesca Turroni, Tiziana Meschi, Marco Mor, Ovidio Bussolati, Marco Ventura

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Targeting glucosylceramide synthase induces antiproliferative and proapoptotic effects in osimertinib-resistant NSCLC cell models by Silvia La Monica, Federica Vacondio, Kamal Eltayeb, Alessio Lodola, Francesco Volta, Martina Viglioli, Francesca Ferlenghi, Francesca Galvani, Maricla Galetti, Mara Bonelli, Claudia Fumarola, Andrea Cavazzoni, Lisa Flammini, Michela Verzè, Roberta Minari, Pier Giorgio Petronini, Marcello Tiseo, Marco Mor, Roberta Alfieri

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