Evaluating the rate of reversal of fentanyl-induced respiratory depression using a novel long-acting naloxone nanoparticle, cNLX-NP by Saadyah E. Averick, Andrew J. Kassick, Daihyun Song, Borui Zhang, Jennifer Vigliaturo, Diego Luengas, Pedro Silva-Ortiz, Marco Pravetoni, Marco Pravetoni, Marco Pravetoni, Michael D. Raleigh

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Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid... by Christine Robinson, Carly Baehr, Shirdi E. Schmiel, Claudia Accetturo, Daniel L. Mueller, Marco Pravetoni

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Housing conditions and microbial environment do not affect the efficacy of vaccines for treatment of opioid use disorders in mice and rats by Bethany Crouse, Li Zhang, Christine Robinson, Yuguang Ban, Jennifer R Vigliaturo, Sabita Roy, Marco Pravetoni

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Effect of currently approved carriers and adjuvants on the pre-clinical efficacy of a conjugate vaccine against oxycodone in mice and rats. by Marco Pravetoni, Jeffrey S Vervacke, Mark D Distefano, Ashli M Tucker, Megan Laudenbach, Paul R Pentel

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Advancing humanized monoclonal antibody for counteracting fentanyl toxicity towards clinical development by Dustin Hicks, Carly Baehr, Pedro Silva-Ortiz, Aaron Khaimraj, Diego Luengas, Fatima A. Hamid, Marco Pravetoni

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A lipidated TLR7/8 adjuvant enhances the efficacy of a vaccine against fentanyl in mice by Shannon M. Miller, Bethany Crouse, Linda Hicks, Hardik Amin, Shelby Cole, Helene G. Bazin, David J. Burkhart, Marco Pravetoni, Jay T. Evans

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Structure-Based Engineering of Monoclonal Antibodies for Improved Binding to Counteract the Effects of Fentanyl and Carfentanil by Justas Rodarte, Carly Baehr, Dustin Hicks, Morgan McGovern, Yue Zhang, Pedro Silva-Ortiz, Bryan Hannon, Sowmya Duddu, Marie Pancera, Marco Pravetoni

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CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections. by Tyler B Rollman, Zachary W Berkebile, Dustin M Hicks, Jason S Hatfield, Priyanka Chauhan, Marco Pravetoni, Mark R Schleiss, Gregg N Milligan, Terry K Morgan, Craig J Bierle

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A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models by Bethany Crouse, Shannon M. Miller, Peter Muelken, Linda Hicks, Jennifer R. Vigliaturo, Cheryl L. Marker, Alonso G. P. Guedes, Paul R. Pentel, Jay T. Evans, Mark G. LeSage, Marco Pravetoni

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Fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge by Addison E. Stone, Sarah E. Scheuermann, Colin N. Haile, Gregory D. Cuny, Marcela Lopez Velasquez, Joshua P. Linhuber, Anantha L. Duddupudi, Jennifer R. Vigliaturo, Marco Pravetoni, Therese A. Kosten, Thomas R. Kosten, Elizabeth B. Norton

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CD56bright cytokine-induced memory-like NK cells and NK-cell engagers synergize against non-small cell lung cancer cancer-stem cells by Paola Orecchia, Maria Cristina Mingari, Martin Felices, Monica Parodi, Luca Roz, Massimo Vitale, Giulia Bertolini, Claudia Cantoni, Maria L Guevara Lopez, Ann Gebo, Stefano Persano, Josephine Maus-Conn, Fabrizio Loiacono, Simona Sivori, Marco Gentili, Federica Facchinetti, Riccardo Ferracini, Daniel A Vallera, Marco Pravetoni

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A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl by Gianna Triller, Evi P. Vlachou, Hamidreza Hashemi, Monique van Straaten, Johan P. Zeelen, Yosip Kelemen, Carly Baehr, Cheryl L. Marker, Sandra Ruf, Anna Svirina, Monica Chandra, Katharina Urban, Anastasia Gkeka, Sebastian Kruse, Andreas Baumann, Aubry K. Miller, Marc Bartel, Marco Pravetoni, C. Erec Stebbins, F. Nina Papavasiliou, Joseph P. Verdi

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