Modeling Alzheimer’s disease using human cell derived brain organoids and 3D models by Sarah Fernandes, Sarah Fernandes, Jasmin Revanna, Jasmin Revanna, Joshua Pratt, Joshua Pratt, Nicholas Hayes, Nicholas Hayes, Maria C. Marchetto, Fred H. Gage

Get full text

Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons by Mark van den Hurk, Shong Lau, Maria C. Marchetto, Jerome Mertens, Shani Stern, Olga Corti, Alexis Brice, Beate Winner, Jürgen Winkler, Fred H. Gage, Cedric Bardy

Get full text

NGLY1 mutations cause protein aggregation in human neurons by Andreea Manole, Thomas Wong, Amanda Rhee, Sammy Novak, Shao-Ming Chin, Katya Tsimring, Andres Paucar, April Williams, Traci Fang Newmeyer, Simon T. Schafer, Idan Rosh, Susmita Kaushik, Rene Hoffman, Songjie Chen, Guangwen Wang, Michael Snyder, Ana Maria Cuervo, Leo Andrade, Uri Manor, Kevin Lee, Jeffrey R. Jones, Shani Stern, Maria C. Marchetto, Fred H. Gage

Get full text

Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients by Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menachem Mendel Percia, Ran Ben Ezer, Maxim N. Shokhirev, Fan Qiu, Simon Schafer, Abed AlFatah Mansour, Kile P. Mangan, Tchelet Stern, Polina Ofer, Yam Stern, Ana Paula Diniz Mendes, Jose Djamus, Lynne Randolph Moore, Ritu Nayak, Sapir Havusha Laufer, Aidan Aicher, Amanda Rhee, Thomas L. Wong, Thao Nguyen, Sara B. Linker, Beate Winner, Beatriz C. Freitas, Eugenia Jones, Irit Sagi, Cedric Bardy, Alexis Brice, Juergen Winkler, Maria C. Marchetto, Fred H. Gage

Get full text