Inactivation of HIPK2 attenuates KRASG12D activity and prevents pancreatic tumorigenesis by Silvia Sozzi, Isabella Manni, Cristiana Ercolani, Maria Grazia Diodoro, Armando Bartolazzi, Francesco Spallotta, Giulia Piaggio, Laura Monteonofrio, Silvia Soddu, Cinzia Rinaldo, Davide Valente

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An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis by Veronica Gatti, Manuela Ferrara, Ilaria Virdia, Silvia Matteoni, Laura Monteonofrio, Simona di Martino, Maria Grazia Diodoro, Giuliana Di Rocco, Cinzia Rinaldo, Silvia Soddu

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EphB2 stem-related and EphA2 progression-related miRNA-based networks in progressive stages of CRC evolution: clinical significance and potential miRNA drivers by Mariangela De Robertis, Tommaso Mazza, Caterina Fusilli, Luisa Loiacono, Maria Luana Poeta, Massimo Sanchez, Emanuela Massi, Giuseppe Lamorte, Maria Grazia Diodoro, Edoardo Pescarmona, Emanuela Signori, Graziano Pesole, Angelo Luigi Vescovi, Jesus Garcia-Foncillas, Vito Michele Fazio

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Coexisting YAP expression and TP53 missense mutations delineates a molecular scenario unexpectedly associated with better survival outcomes in advanced gastric cancer by Matteo Pallocca, Frauke Goeman, Francesca De Nicola, Elisa Melucci, Francesca Sperati, Irene Terrenato, Laura Pizzuti, Beatrice Casini, Enzo Gallo, Carla Azzurra Amoreo, Patrizia Vici, Luigi Di Lauro, Simonetta Buglioni, Maria Grazia Diodoro, Edoardo Pescarmona, Marco Mazzotta, Maddalena Barba, Maurizio Fanciulli, Ruggero De Maria, Gennaro Ciliberto, Marcello Maugeri-Saccà

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HSF-1/miR-145-5p transcriptional axis enhances hyperthermic intraperitoneal chemotherapy efficacy on peritoneal ovarian carcinosis by Silvia Di Agostino, Valeria Canu, Sara Donzelli, Claudio Pulito, Andrea Sacconi, Federica Ganci, Fabio Valenti, Frauke Goeman, Stefano Scalera, Francesca Rollo, Anna Bagnato, Maria Grazia Diodoro, Enrico Vizza, Mariantonia Carosi, Beatrice Rufini, Orietta Federici, Manuel Giofrè, Fabio Carboni, Paola Muti, Gennaro Ciliberto, Sabrina Strano, Mario Valle, Giovanni Blandino

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The clinical significance of PD-L1 in advanced gastric cancer is dependent on ARID1A mutations and ATM expression by Simonetta Buglioni, Elisa Melucci, Francesca Sperati, Matteo Pallocca, Irene Terrenato, Francesca De Nicola, Frauke Goeman, Beatrice Casini, Carla Azzurra Amoreo, Enzo Gallo, Maria Grazia Diodoro, Edoardo Pescarmona, Patrizia Vici, Domenico Sergi, Laura Pizzuti, Luigi Di Lauro, Marco Mazzotta, Maddalena Barba, Maurizio Fanciulli, Ilio Vitale, Ruggero De Maria, Gennaro Ciliberto, Marcello Maugeri-Saccà

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Interrogating colorectal cancer metastasis to liver: a search for clinically viable compounds and mechanistic insights in colorectal cancer Patient Derived Organoids by Mario Cioce, Maria Rita Fumagalli, Sara Donzelli, Frauke Goeman, Valeria Canu, Daniela Rutigliano, Giulia Orlandi, Andrea Sacconi, Claudio Pulito, Alina Catalina Palcau, Maurizio Fanciulli, Aldo Morrone, Maria Grazia Diodoro, Marco Caricato, Anna Crescenzi, Martina Verri, Vito Michele Fazio, Stefano Zapperi, Massimo Levrero, Sabrina Strano, Gian Luca Grazi, Caterina La Porta, Giovanni Blandino

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Expression of the Hippo transducer TAZ in association with WNT pathway mutations impacts survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy by Elisa Melucci, Beatrice Casini, Livia Ronchetti, Laura Pizzuti, Francesca Sperati, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Enzo Gallo, Carla Azzurra Amoreo, Domenico Sergi, Irene Terrenato, Patrizia Vici, Luigi Di Lauro, Maria Grazia Diodoro, Edoardo Pescarmona, Maddalena Barba, Marco Mazzotta, Marcella Mottolese, Maurizio Fanciulli, Gennaro Ciliberto, Ruggero De Maria, Simonetta Buglioni, Marcello Maugeri-Saccà

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A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer by Alessandra Viel, Alessandro Bruselles, Ettore Meccia, Mara Fornasarig, Michele Quaia, Vincenzo Canzonieri, Eleonora Policicchio, Emanuele Damiano Urso, Marco Agostini, Maurizio Genuardi, Emanuela Lucci-Cordisco, Tiziana Venesio, Aline Martayan, Maria Grazia Diodoro, Lupe Sanchez-Mete, Vittoria Stigliano, Filomena Mazzei, Francesca Grasso, Alessandro Giuliani, Marta Baiocchi, Roberta Maestro, Giuseppe Giannini, Marco Tartaglia, Ludmil B. Alexandrov, Margherita Bignami

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