The ideal time of systemic metronidazole and amoxicillin administration in the treatment of severe periodontitis: study protocol for a randomized controlled trial by Magda Feres, Belén Retamal-Valdes, Maria Josefa Mestnik, Luciene Cristina de Figueiredo, Marcelo Faveri, Poliana M. Duarte, Aretuza Fritoli, Elisangela Faustino, Maria Luisa Silveira Souto, Michelle de Franco Rodrigues, Marcela Giudicissi, Bárbara Campos Lara Nogueira, Luciana Saraiva, Giuseppe Alexandre Romito, Cláudio Mendes Pannuti

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