Incidence and determinants of hematotoxicity in acute lymphoblastic leukemia children who received 6-mercaptopurine based maintenance therapy in Addis Ababa, Ethiopia by Awol Mekonnen Ali, Haileyesus Adam, Daniel Hailu, Marieke J. H. Coenen, Rawleigh Howe, Teferra Abula

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Incidence and determinants of hematotoxicity in acute lymphoblastic leukemia children who received 6-mercaptopurine based maintenance therapy in Addis Ababa, Ethiopia. by Awol Mekonnen Ali, Haileyesus Adam, Daniel Hailu, Marieke J H Coenen, Rawleigh Howe, Teferra Abula

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Genetic variants of genes involved in thiopurine metabolism pathway are associated with 6-mercaptopurine toxicity in pediatric acute lymphoblastic leukemia patients from Ethiopia by Awol Mekonnen Ali, Haileyesus Adam, Daniel Hailu, Ephrem Engidawork, Rawleigh Howe, Teferra Abula, Marieke J. H. Coenen

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Pain predict genetics: protocol for a prospective observational study of clinical and genetic factors to predict the development of postoperative pain by Song Li, Kris C P Vissers, Marieke J H Coenen, Regina L M van Boekel, Sandra A S van den Heuvel

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Pharmacogenetics of chemotherapy treatment response and -toxicities in patients with osteosarcoma: a systematic review by Evelien G. E. Hurkmans, Annouk C. A. M. Brand, Job A. J. Verdonschot, D. Maroeska W. M. te Loo, Marieke J. H. Coenen

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Association of the neutrophil to lymphocyte ratio and white blood cell count with response to pharmacotherapy in unipolar psychotic depression: An exploratory analysis by Cornelis F. Vos, Tom K. Birkenhäger, Willem A. Nolen, Walter W. van den Broek, Marieke J.H. Coenen, Sophie E. ter Hark, Robbert-Jan Verkes, Joost G.E. Janzing

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A replication study of the association between rheumatoid arthritis and deletion of the late cornified envelope genes LCE3B and LCE3C. by Judith G M Bergboer, Maša Umićević-Mirkov, Jaap Fransen, Martin den Heijer, Barbara Franke, Piet L C M van Riel, Joost Schalkwijk, Marieke J H Coenen, Nijmegen Biomedical Study principal investigators

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Correction: A genetic risk score to predict treatment nonresponse in psychotic depression by Sophie E. ter Hark, Marieke J. H. Coenen, Cornelis F. Vos, Rob E. Aarnoutse, Willem A. Nolen, Tom K. Birkenhager, Walter W. van den Broek, Arnt F. A. Schellekens, Robbert-Jan Verkes, Joost G. E. Janzing

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A genetic risk score to predict treatment nonresponse in psychotic depression by Sophie E. ter Hark, Marieke J. H. Coenen, Cornelis F. Vos, Rob E. Aarnoutse, Willem A. Nolen, Tom K. Birkenhager, Walter W. van den Broek, Arnt F. A. Schellekens, Robbert-Jan Verkes, Joost G. E. Janzing

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Analysis of Drug Metabolizing Gene Panel in Osteosarcoma Patients Identifies Association Between Variants in SULT1E1, CYP2B6 and CYP4F8 and Methotrexate Levels and Toxicities by Evelien G. E. Hurkmans, Marije J. Klumpers, Sita H. Vermeulen, Melanie M. Hagleitner, Uta Flucke, H. W. Bart Schreuder, Hans Gelderblom, Johannes Bras, Henk-Jan Guchelaar, Marieke J. H. Coenen, D. Maroeska W. M. te Loo

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Evolution of Dihydropyrimidine Dehydrogenase Diagnostic Testing in a Single Center during an 8-Year Period of Time by Marieke J.H. Coenen, PhD, Aimée D.C. Paulussen, PhD, Marc Breuer, BSc, Martijn Lindhout, BSc, Demis C.J. Tserpelis, BSc, Anja Steyls, BSc, Jörgen Bierau, PhD, Bianca J.C. van den Bosch, PhD

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Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant hetero... by Melanie M Hagleitner, Marieke J H Coenen, Ana Patino-Garcia, Eveline S J M de Bont, Anna Gonzalez-Neira, Hanneke I Vos, Frank N van Leeuwen, Hans Gelderblom, Peter M Hoogerbrugge, Henk-Jan Guchelaar, Maroeska W M Te Loo

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Validation study of existing gene expression signatures for anti-TNF treatment in patients with rheumatoid arthritis. by Erik J M Toonen, Christian Gilissen, Barbara Franke, Wietske Kievit, Agnes M Eijsbouts, Alfons A den Broeder, Simon V van Reijmersdal, Joris A Veltman, Hans Scheffer, Timothy R D J Radstake, Piet L C M van Riel, Pilar Barrera, Marieke J H Coenen

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Genetic variants in toll-like receptors are not associated with rheumatoid arthritis susceptibility or anti-tumour necrosis factor treatment outcome. by Marieke J H Coenen, Christian Enevold, Pilar Barrera, Mascha M V A P Schijvenaars, Erik J M Toonen, Hans Scheffer, Leonid Padyukov, Alf Kastbom, Lars Klareskog, Anne Barton, Wietske Kievit, Maarten J Rood, Tim L Jansen, Dorine Swinkels, Piet L C M van Riel, Barbara Franke, Klaus Bendtzen, Timothy R D J Radstake

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Methodology of the DCCSS later fatigue study: a model to investigate chronic fatigue in long-term survivors of childhood cancer by Adriaan Penson, Sylvia van Deuren, Ewald Bronkhorst, Ellen Keizer, Tom Heskes, Marieke J. H. Coenen, Judith G. M. Rosmalen, Wim J. E. Tissing, Helena J. H. van der Pal, Andrica C. H. de Vries, Marry M. van den Heuvel-Eibrink, Sebastian Neggers, Birgitta A. B. Versluys, Marloes Louwerens, Margriet van der Heiden-van der Loo, Saskia M. F. Pluijm, Martha Grootenhuis, Nicole Blijlevens, Leontien C. M. Kremer, Eline van Dulmen-den Broeder, Hans Knoop, Jacqueline Loonen

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Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. by Alexandra Zhernakova, Eli A Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A Festen, Lude Franke, Harm-Jan Westra, Rudolf S N Fehrmann, Fina A S Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W Ryan, Graham Turner, Elisabeth Brouwer, Marcel D Posthumus, Elaine F Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J H Coenen, Timothy R D J Radstake, Piet L C M van Riel, Yonghong Li, Paul I W de Bakker, Peter K Gregersen, Jane Worthington, Katherine A Siminovitch, Lars Klareskog, Tom W J Huizinga, Cisca Wijmenga, Robert M Plenge

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SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin by Evelien G. E. Hurkmans, Jan B. Koenderink, Jeroen J. M. W. van den Heuvel, Yvonne M. H. Versleijen-Jonkers, Melissa H. S. Hillebrandt-Roeffen, Johanne M. Groothuismink, Hanneke I. Vos, Winette T. A. van der Graaf, Winette T. A. van der Graaf, Uta Flucke, Grigor Muradjan, Hendrik W. B. Schreuder, Melanie M. Hagleitner, Han G. Brunner, Hans Gelderblom, Anne-Marie Cleton-Jansen, Henk-Jan Guchelaar, Eveline S. J. M. de Bont, Daan J. Touw, G. Jan Nijhoff, Leontien C. M. Kremer, Huib Caron, Rachael Windsor, Ana Patiño-García, Anna González-Neira, Federica Saletta, Geoff McCowage, Sumanth Nagabushan, Sumanth Nagabushan, Daniel Catchpoole, D. Maroeska W. M. te Loo, Marieke J. H. Coenen

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Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia by Evelien G. E. Hurkmans, Marije J. Klumpers, Cinzia Dello Russo, Cinzia Dello Russo, Ward De Witte, Henk-Jan Guchelaar, Hans Gelderblom, Anne-Marie Cleton-Jansen, Sita H. Vermeulen, Suzanne Kaal, Winette T. A. van der Graaf, Winette T. A. van der Graaf, Uta Flucke, Corrie E. M. Gidding, Hendrik W. B. Schreuder, Eveline S. J. M. de Bont, Huib N. Caron, Giovanna Gattuso, Elisabetta Schiavello, Monica Terenziani, Maura Massimino, Geoff McCowage, Sumanth Nagabushan, Sumanth Nagabushan, Anuja Limaye, Victoria Rose, Daniel Catchpoole, Andrea L. Jorgensen, Christopher Barton, Lucy Delaney, Daniel B. Hawcutt, Daniel B. Hawcutt, Munir Pirmohamed, Barry Pizer, Marieke J. H. Coenen, D. Maroeska W. M. te Loo

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Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene. by Yukinori Okada, Dorothee Diogo, Jeffrey D Greenberg, Faten Mouassess, Walid A L Achkar, Robert S Fulton, Joshua C Denny, Namrata Gupta, Daniel Mirel, Stacy Gabriel, Gang Li, Joel M Kremer, Dimitrios A Pappas, Robert J Carroll, Anne E Eyler, Gosia Trynka, Eli A Stahl, Jing Cui, Richa Saxena, Marieke J H Coenen, Henk-Jan Guchelaar, Tom W J Huizinga, Philippe Dieudé, Xavier Mariette, Anne Barton, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, Larry W Moreland, S Louis Bridges, Corinne Miceli-Richard, Hyon K Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, Towfique Raj, Philip L De Jager, Soumya Raychaudhuri, Jane Worthington, Leonid Padyukov, Lars Klareskog, Katherine A Siminovitch, Peter K Gregersen, Elaine R Mardis, Thurayya Arayssi, Layla A Kazkaz, Robert M Plenge

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TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits. by Dorothée Diogo, Lisa Bastarache, Katherine P Liao, Robert R Graham, Robert S Fulton, Jeffrey D Greenberg, Steve Eyre, John Bowes, Jing Cui, Annette Lee, Dimitrios A Pappas, Joel M Kremer, Anne Barton, Marieke J H Coenen, Barbara Franke, Lambertus A Kiemeney, Xavier Mariette, Corrine Richard-Miceli, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, J Bart A Crusius, Michael T Nurmohamed, Fina Kurreeman, Ted R Mikuls, Yukinori Okada, Eli A Stahl, David E Larson, Tracie L Deluca, Michelle O'Laughlin, Catrina C Fronick, Lucinda L Fulton, Roman Kosoy, Michael Ransom, Tushar R Bhangale, Ward Ortmann, Andrew Cagan, Vivian Gainer, Elizabeth W Karlson, Isaac Kohane, Shawn N Murphy, Javier Martin, Alexandra Zhernakova, Lars Klareskog, Leonid Padyukov, Jane Worthington, Elaine R Mardis, Michael F Seldin, Peter K Gregersen, Timothy Behrens, Soumya Raychaudhuri, Joshua C Denny, Robert M Plenge

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