Improved estimation of overall survival and progression-free survival for state transition modeling by Peter C Wigfield, Bart Heeg, Mario Ouwens

Relationship between risk, cumulative burden of exacerbations and mortality in patients with COPD: modelling analysis using data from the ETHOS study by Kirsty Rhodes, Martin Jenkins, Enrico de Nigris, Magnus Aurivillius, Mario Ouwens

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Systematic review and network meta-analysis of the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler in comparison with other long-acting muscarinic an... by Mohd Kashif Siddiqui, Pragya Shukla, Martin Jenkins, Mario Ouwens, Deniz Guranlioglu, Patrick Darken, Mousumi Biswas

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Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 2; referees: 2 approved] by Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, Sandra Leonard

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Real world evidence (RWE) – a disruptive innovation or the quiet evolution of medical evidence generation? [version 1; referees: 2 approved] by Sajan Khosla, Robert White, Jesús Medina, Mario Ouwens, Cathy Emmas, Tim Koder, Gary Male, Sandra Leonard

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Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data. by Yasunori Aoki, Claudia S Cabrera, Mario Ouwens, Krister Bamberg, Jenny Nyström, Itamar Raz, Benjamin M Scirica, Bengt Hamrén, Peter J Greasley, Dinko Rekić

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Bilirubin levels and kidney function decline: An analysis of clinical trial and real world data by Yasunori Aoki, Claudia S. Cabrera, Mario Ouwens, Krister Bamberg, Jenny Nyström, Itamar Raz, Benjamin M. Scirica, Bengt Hamrén, Peter J. Greasley, Dinko Rekić

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EXAcerbations of COPD and their OutcomeS on CardioVascular diseases (EXACOS-CV) Programme: protocol of multicountry observational cohort studies by Jennifer K Quint, Hana Müllerova, Clementine Nordon, Nathaniel M Hawkins, Jonathan Marshall, Sami O Simons, Kirsty Rhodes, Claus F Vogelmeier, Mario Ouwens, Edeltraut Garbe

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Protocol for the development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: SPIRIT-SURROGATE and CONSORT-SURROGATE by Martin Offringa, Nancy J Butcher, Derek Stewart, An-Wen Chan, Oriana Ciani, Philippa Davies, Christopher J Weir, Mario Ouwens, Dalia Dawoud, Sylwia Bujkiewicz, Anthony Muchai Manyara

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Cost-effectiveness of ticagrelor plus aspirin versus aspirin in acute ischaemic stroke or transient ischaemic attack: an economic evaluation of the THALES trial by Yongjun Wang, S Claiborne Johnston, Pierre Amarenco, Carl Mellström, Mario Ouwens, Scott R Evans, Ritika Jain, Stefan James, Hans Denison, Per Ladenvall, Carlos A Molina, Anders Himmelmann, Mikael Knutsson, Amarjeet Tank, Klas Rikner

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A framework for the definition and interpretation of the use of surrogate endpoints in interventional trialsResearch in context by Oriana Ciani, Anthony M. Manyara, Philippa Davies, Derek Stewart, Christopher J. Weir, Amber E. Young, Jane Blazeby, Nancy J. Butcher, Sylwia Bujkiewicz, An-Wen Chan, Dalia Dawoud, Martin Offringa, Mario Ouwens, Asbjørn Hróbjartssson, Alain Amstutz, Luca Bertolaccini, Vito Domenico Bruno, Declan Devane, Christina D.C.M. Faria, Peter B. Gilbert, Ray Harris, Marissa Lassere, Lucio Marinelli, Sarah Markham, John H. Powers, Yousef Rezaei, Laura Richert, Falk Schwendicke, Larisa G. Tereshchenko, Achilles Thoma, Alparslan Turan, Andrew Worrall, Robin Christensen, Gary S. Collins, Joseph S. Ross, Rod S. Taylor

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