Editorial: Broadening our understanding of the impact of infections on the developing central nervous system - from basic to clinical sciences by Mark A. Travassos, Ursula K. Rohlwink, Elizabeth W. Tucker

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272 Differential expression of two Plasmodium falciparum variant surface antigen families in Malian children with cerebral malaria compared to mild malaria by Jonathan G. Lawton, Albert E. Zhou, Drissa Coulibaly, Emily M. Stucke, Antoine Dara, Matthew B. Laurens, Joana C. Silva, Mahamadou A. Thera, Mark A. Travassos

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STRIDE: a command-line HMM-based identifier and sub-classifier of Plasmodium falciparum RIFIN and STEVOR variant surface antigen families by Albert E. Zhou, Zalak V. Shah, Katie R. Bradwell, James B. Munro, Andrea A. Berry, David Serre, Shannon Takala-Harrison, Timothy D. O’Connor, Joana C. Silva, Mark A. Travassos

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Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali by Drissa Coulibaly, Abdoulaye K. Kone, Bourama Kane, Bouréima Guindo, Bourama Tangara, Mody Sissoko, Fayçal Maiga, Karim Traore, Aichatou Diawara, Amidou Traore, Ali Thera, Mahamadou S. Sissoko, Ogobara K. Doumbo, Mark A. Travassos, Mahamadou A. Thera

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Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study by Sean D. McCabe, E. Adrianne Hammershaimb, David Cheng, Andy Shi, Derek Shyr, Shuting Shen, Lyndsey D. Cole, Jessica R. Cataldi, William Allen, Ryan Probasco, Ben Silbermann, Feng Zhang, Regan Marsh, Mark A. Travassos, Xihong Lin

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Host and Parasite Transcriptomic Changes upon Successive <named-content content-type="genus-species">Plasmodium falciparum</named-content> Infections in Early Childhood by Katie R. Bradwell, Drissa Coulibaly, Abdoulaye K. Koné, Matthew B. Laurens, Ahmadou Dembélé, Youssouf Tolo, Karim Traoré, Amadou Niangaly, Andrea A. Berry, Bourema Kouriba, Christopher V. Plowe, Ogobara K. Doumbo, Kirsten E. Lyke, Shannon Takala-Harrison, Mahamadou A. Thera, Mark A. Travassos, David Serre

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Immunization Coverage Surveys and Linked Biomarker Serosurveys in Three Regions in Ethiopia. by Mark A Travassos, Berhane Beyene, Zenaw Adam, James D Campbell, Nigisti Mulholland, Seydou S Diarra, Tassew Kassa, Lisa Oot, Jenny Sequeira, Mardi Reymann, William C Blackwelder, Yukun Wu, Inna Ruslanova, Jaya Goswami, Samba O Sow, Marcela F Pasetti, Robert Steinglass, Amha Kebede, Myron M Levine

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Malian adults maintain serologic responses to virulent PfEMP1s amid seasonal patterns of fluctuation by Noah T. Ventimiglia, Emily M. Stucke, Drissa Coulibaly, Andrea A. Berry, Kirsten E. Lyke, Matthew B. Laurens, Jason A. Bailey, Matthew Adams, Amadou Niangaly, Abdoulaye K. Kone, Shannon Takala-Harrison, Bourema Kouriba, Ogobara K. Doumbo, Phillip L. Felgner, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos

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Immune gene expression changes more during a malaria transmission season than between consecutive seasons by Kieran Tebben, Salif Yirampo, Drissa Coulibaly, Abdoulaye K. Koné, Matthew B. Laurens, Emily M. Stucke, Ahmadou Dembélé, Youssouf Tolo, Karim Traoré, Amadou Niangaly, Andrea A. Berry, Bourèma Kouriba, Christopher V. Plowe, Ogobara K. Doumbo, Kirsten E. Lyke, Shannon Takala-Harrison, Mahamadou A. Thera, Mark A. Travassos, David Serre

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Gene expression analyses reveal differences in children’s response to malaria according to their age by Kieran Tebben, Salif Yirampo, Drissa Coulibaly, Abdoulaye K. Koné, Matthew B. Laurens, Emily M. Stucke, Ahmadou Dembélé, Youssouf Tolo, Karim Traoré, Amadou Niangaly, Andrea A. Berry, Bourema Kouriba, Christopher V. Plowe, Ogobara K. Doumbo, Kirsten E. Lyke, Shannon Takala-Harrison, Mahamadou A. Thera, Mark A. Travassos, David Serre

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Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles. by Kieran Tebben, Salif Yirampo, Drissa Coulibaly, Abdoulaye K Koné, Matthew B Laurens, Emily M Stucke, Ahmadou Dembélé, Youssouf Tolo, Karim Traoré, Amadou Niangaly, Andrea A Berry, Bourema Kouriba, Christopher V Plowe, Ogobara K Doumbo, Kirsten E Lyke, Shannon Takala-Harrison, Mahamadou A Thera, Mark A Travassos, David Serre

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High-throughput detection of eukaryotic parasites and arboviruses in mosquitoes by Matthew V. Cannon, Haikel N. Bogale, Devika Bhalerao, Kalil Keita, Denka Camara, Yaya Barry, Moussa Keita, Drissa Coulibaly, Abdoulaye K. Kone, Ogobara K. Doumbo, Mahamadou A. Thera, Christopher V. Plowe, Mark A. Travassos, Seth R. Irish, Joshua Yeroshefsky, Jeannine Dorothy, Brian Prendergast, Brandyce St. Laurent, Megan L. Fritz, David Serre

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New var reconstruction algorithm exposes high var sequence diversity in a single geographic location in Mali by Antoine Dara, Elliott F. Drábek, Mark A. Travassos, Kara A. Moser, Arthur L. Delcher, Qi Su, Timothy Hostelley, Drissa Coulibaly, Modibo Daou, Ahmadou Dembele, Issa Diarra, Abdoulaye K. Kone, Bourema Kouriba, Matthew B. Laurens, Amadou Niangaly, Karim Traore, Youssouf Tolo, Claire M. Fraser, Mahamadou A. Thera, Abdoulaye A. Djimde, Ogobara K. Doumbo, Christopher V. Plowe, Joana C. Silva

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Immunoprofiles associated with controlled human malaria infection and naturally acquired immunity identify a shared IgA pre-erythrocytic immunoproteome by Andrea A. Berry, Joshua M. Obiero, Mark A. Travassos, Amed Ouattara, Drissa Coulibaly, Matthew Adams, Rafael Ramiro de Assis, Aarti Jain, Omid Taghavian, Andrew Sy, Rie Nakajima, Algis Jasinskas, Matthew B. Laurens, Shannon Takala-Harrison, Bourema Kouriba, Abdoulaye K. Kone, Ogobara K. Doumbo, B. Kim Lee Sim, Stephen L. Hoffman, Christopher V. Plowe, Mahamadou A. Thera, Philip L. Felgner, Kirsten E. Lyke

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Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag by Emily M. Stucke, Amadou Niangaly, Andrea A. Berry, Jason A. Bailey, Drissa Coulibaly, Amed Ouattara, Kirsten E. Lyke, Matthew B. Laurens, Antoine Dara, Matthew Adams, Jozelyn Pablo, Algis Jasinskas, Rie Nakajima, Albert E. Zhou, Sonia Agrawal, DeAnna J. Friedman-Klabanoff, Shannon Takala-Harrison, Bourema Kouriba, Abdoulaye K. Kone, J. Alexandra Rowe, Ogobara K. Doumbo, Philip L. Felgner, Mahamadou A. Thera, Christopher V. Plowe, Mark A. Travassos

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Successful Profiling of Plasmodium falciparum var Gene Expression in Clinical Samples via a Custom Capture Array by Emily M. Stucke, Antoine Dara, Ankit Dwivedi, Theresa K. Hodges, Sandra Ott, Drissa Coulibaly, Abdoulaye K. Koné, Karim Traoré, Bouréima Guindo, Bourama M. Tangara, Amadou Niangaly, Modibo Daou, Issa Diarra, Youssouf Tolo, Mody Sissoko, Luke J. Tallon, Lisa Sadzewicz, Albert E. Zhou, Matthew B. Laurens, Amed Ouattara, Bourema Kouriba, Ogobara K. Doumbo, Shannon Takala-Harrison, David Serre, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos, Joana C. Silva

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Natural immunity to malaria preferentially targets the endothelial protein C receptor-binding regions of PfEMP1s by Madison A. Tewey, Drissa Coulibaly, Jonathan G. Lawton, Emily M. Stucke, Albert E. Zhou, Andrea A. Berry, Jason A. Bailey, Andrew Pike, Antoine Dara, Amed Ouattara, Kirsten E. Lyke, Olukemi Ifeonu, Matthew B. Laurens, Matthew Adams, Shannon Takala-Harrison, Amadou Niangaly, Bourema Kouriba, Abdoulaye K. Koné, J. Alexandra Rowe, Ogobara K. Doumbo, Jigar J. Patel, John C. Tan, Philip L. Felgner, Christopher V. Plowe, Mahamadou A. Thera, Mark A. Travassos

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Antibodies to Peptides in Semiconserved Domains of RIFINs and STEVORs Correlate with Malaria Exposure by Albert E. Zhou, Andrea A. Berry, Jason A. Bailey, Andrew Pike, Antoine Dara, Sonia Agrawal, Emily M. Stucke, Amed Ouattara, Drissa Coulibaly, Kirsten E. Lyke, Matthew B. Laurens, Matthew Adams, Shannon Takala-Harrison, Jozelyn Pablo, Algis Jasinskas, Rie Nakajima, Amadou Niangaly, Bourema Kouriba, Abdoulaye K. Kone, J. Alexandra Rowe, Ogobara K. Doumbo, Mahamadou A. Thera, Jigar J. Patel, John C. Tan, Philip L. Felgner, Christopher V. Plowe, Mark A. Travassos

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