Ophthalmologic Baseline Characteristics and 2-Year Ophthalmologic Safety Profile of Pramipexole IR Compared with Ropinirole IR in Patients with Early Parkinson’s Disease von William Seiple, Danna Jennings, Richard B. Rosen, Leona Borchert, Lee Canale, Nora Fagan, Mark Forrest Gordon

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Minimal Clinically Important Difference in Parkinson’s Disease as Assessed in Pivotal Trials of Pramipexole Extended Release von Robert A. Hauser, Mark Forrest Gordon, Yoshikuni Mizuno, Werner Poewe, Paolo Barone, Anthony H. Schapira, Olivier Rascol, Catherine Debieuvre, Mandy Fräßdorf

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Which glaucoma patients should be monitored at home and exploration of clinician perceptions on home monitoring? a survey of glaucoma specialists in the UK von Graeme Maclennan, Augusto Azuara-Blanco, Anthony J King, Katie Gillies, Mark Forrest, Rodolfo Hernández, Andrew Tatham, Uma Alagappan, Carrie Stewart, Darian Shotton

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Is the association between blood pressure and cognition in the oldest-old modified by physical, vascular or brain pathology markers? The EMIF-AD 90 + Study von Nienke Legdeur, Justine E. Moonen, Maryam Badissi, Carole H. Sudre, Wiesje Pelkmans, Mark Forrest Gordon, Frederik Barkhof, Mike Peters, Pieter Jelle Visser, Majon Muller

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Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease von Shani Cohen, Zeev Waks, Jordan J. Elm, Mark Forrest Gordon, Igor D. Grachev, Leehee Navon-Perry, Shai Fine, Iris Grossman, Spyros Papapetropoulos, Juha-Matti Savola

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Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case–control study using European electronic health records von Johan van Der Lei, Robert Stewart, Pieter Jelle Visser, Talita Duarte-Salles, Myriam Alexander, David Ansell, Alessandro Pasqua, Francesco Lapi, Paul Avillach, Lars Pedersen, Gayan Perera, Mark Forrest Gordon, Miguel Angel Mayer

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Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT von Karen Innes, Irfan Ahmed, Jemma Hudson, Rodolfo Hernández, Katie Gillies, Rebecca Bruce, Victoria Bell, Alison Avenell, Jane Blazeby, Miriam Brazzelli, Seonaidh Cotton, Bernard Croal, Mark Forrest, Graeme MacLennan, Peter Murchie, Samantha Wileman, Craig Ramsay

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Provision of the progestogen-only pill by community pharmacies as bridging contraception for women receiving emergency contraception: the Bridge-it RCT von Sharon T Cameron, Anna Glasier, Lisa McDaid, Andrew Radley, Susan Patterson, Paula Baraitser, Judith Stephenson, Richard Gilson, Claire Battison, Kathleen Cowle, Thenmalar Vadiveloo, Anne Johnstone, Alessandra Morelli, Beatriz Goulao, Mark Forrest, Alison McDonald, John Norrie

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HEALTH: laparoscopic supracervical hysterectomy versus second-generation endometrial ablation for the treatment of heavy menstrual bleeding: study protocol for a randomised control... von Kevin Cooper, Kirsty McCormack, Suzanne Breeman, Jessica Wood, Neil W. Scott, Justin Clark, Jed Hawe, Robert Hawthorn, Kevin Phillips, Angela Hyde, Alison McDonald, Mark Forrest, Samantha Wileman, Graham Scotland, John Norrie, Siladitya Bhattacharya, for the HEALTH Study Group

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The TOPSY pessary self-management intervention for pelvic organ prolapse: a study protocol for the process evaluation von Carol Bugge, Rohna Kearney, Melanie Dembinsky, Aethele Khunda, Margaret Graham, Wael Agur, Suzanne Breeman, Lucy Dwyer, Andrew Elders, Mark Forrest, Kirsteen Goodman, Karen Guerrero, Christine Hemming, Helen Mason, Doreen McClurg, Lynn Melone, John Norrie, Ranee Thakar, Suzanne Hagen

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Correction: Safety of Deutetrabenazine for the Treatment of Tardive Dyskinesia and Chorea Associated with Huntington Disease von Samuel Frank, Karen E. Anderson, Hubert H. Fernandez, Robert A. Hauser, Daniel O. Claassen, David Stamler, Stewart A. Factor, Joohi Jimenez-Shahed, Hadas Barkay, Amanda Wilhelm, Jessica K. Alexander, Nayla Chaijale, Steve Barash, Juha-Matti Savola, Mark Forrest Gordon, Maria Chen

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Safety of Deutetrabenazine for the Treatment of Tardive Dyskinesia and Chorea Associated with Huntington Disease von Samuel Frank, Karen E. Anderson, Hubert H. Fernandez, Robert A. Hauser, Daniel O. Claassen, David Stamler, Stewart A. Factor, Joohi Jimenez-Shahed, Hadas Barkay, Amanda Wilhelm, Jessica K. Alexander, Nayla Chaijale, Steve Barash, Juha-Matti Savola, Mark Forrest Gordon, Maria Chen

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Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): study protocol for a randomised controll... von Lynda Constable, Nikki Cotterill, David Cooper, Cathryn Glazener, Marcus J. Drake, Mark Forrest, Chris Harding, Mary Kilonzo, Graeme MacLennan, Kirsty McCormack, Alison McDonald, Anthony Mundy, John Norrie, Robert Pickard, Craig Ramsay, Rebecca Smith, Samantha Wileman, Paul Abrams, (Chief Investigator) for the MASTER Study Group

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Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT von Steve Turner, Seonaidh Cotton, Jessica Wood, Victoria Bell, Edwin-Amalraj Raja, Neil W Scott, Heather Morgan, Louisa Lawrie, David Emele, Charlotte Kennedy, Graham Scotland, Shona Fielding, Graeme MacLennan, John Norrie, Mark Forrest, Erol Gaillard, Johan de Jongeste, Marielle Pijnenburg, Mike Thomas, David Price

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Clinical and cost‐effectiveness of pessary self‐management versus clinic-based care for pelvic organ prolapse in women: the TOPSY RCT with process evaluation von Carol Bugge, Suzanne Hagen, Andrew Elders, Helen Mason, Kirsteen Goodman, Melanie Dembinsky, Lynn Melone, Catherine Best, Sarkis Manoukian, Lucy Dwyer, Aethele Khunda, Margaret Graham, Wael Agur, Suzanne Breeman, Jane Culverhouse, Angela Forrest, Mark Forrest, Karen Guerrero, Christine Hemming, Doreen McClurg, John Norrie, Ranee Thakar, Rohna Kearney

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Clinical effectiveness of vaginal pessary self-management vs clinic-based care for pelvic organ prolapse (TOPSY): a randomised controlled superiority trialResearch in context von Suzanne Hagen, Rohna Kearney, Kirsteen Goodman, Catherine Best, Andrew Elders, Lynn Melone, Lucy Dwyer, Melanie Dembinsky, Margaret Graham, Wael Agur, Suzanne Breeman, Jane Culverhouse, Angela Forrest, Mark Forrest, Karen Guerrero, Christine Hemming, Aethele Khunda, Sarkis Manoukian, Helen Mason, Doreen McClurg, John Norrie, Ranee Thakar, Carol Bugge

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Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT von Robert Pickard, Beatriz Goulao, Sonya Carnell, Jing Shen, Graeme MacLennan, John Norrie, Matt Breckons, Luke Vale, Paul Whybrow, Tim Rapley, Rebecca Forbes, Stephanie Currer, Mark Forrest, Jennifer Wilkinson, Elaine McColl, Daniela Andrich, Stewart Barclay, Jonathan Cook, Anthony Mundy, James N’Dow, Stephen Payne, Nick Watkin

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Clinical and cost-effectiveness of vaginal pessary self-management compared to clinic-based care for pelvic organ prolapse: protocol for the TOPSY randomised controlled trial von Suzanne Hagen, Rohna Kearney, Kirsteen Goodman, Lynn Melone, Andrew Elders, Sarkis Manoukian, Wael Agur, Catherine Best, Suzanne Breeman, Melanie Dembinsky, Lucy Dwyer, Mark Forrest, Margaret Graham, Karen Guerrero, Christine Hemming, Aethele Khunda, Helen Mason, Doreen McClurg, John Norrie, Anastasia Karachalia-Sandri, Ranee Thakar, Carol Bugge

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Pragmatic cluster randomised cohort cross-over trial to determine the effectiveness of bridging from emergency to regular contraception: the Bridge-It study protocol von Anne Johnstone, Judith M Stephenson, Andrew Radley, Kaye Wellings, Paula Baraitser, Alison McDonald, James Trussell, Richard Gilson, Lisa Mcdaid, Sharon Tracey Cameron, Anna Glasier, Claire Battison, Sarah Cameron, Kathleen Cowle, Mark Forrest, Beatriz Goulao, Susan Patterson, Deirdre Sally, Nicola Stewart, Lucy Michie, Joanna Loudon, Kirsten Stuart, Emily Whittaker

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The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: the (UK-REBOA) multicentre RCT von Jan O Jansen, Jemma Hudson, Charlotte Kennedy, Claire Cochran, Graeme MacLennan, Katie Gillies, Robbie Lendrum, Samy Sadek, Dwayne Boyers, Gillian Ferry, Louisa Lawrie, Mintu Nath, Seonaidh Cotton, Samantha Wileman, Mark Forrest, Karim Brohi, Tim Harris, Fiona Lecky, Chris Moran, Jonathan J Morrison, John Norrie, Alan Paterson, Nigel Tai, Nick Welch, Marion K Campbell

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