The Importance of Global Studies of the Genetics of Type 2 Diabetes by Mark I. McCarthy

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Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci. by Martijn van de Bunt, Adrian Cortes, IGAS Consortium, Matthew A Brown, Andrew P Morris, Mark I McCarthy

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Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study. by Michael Wainberg, Anubha Mahajan, Anshul Kundaje, Mark I McCarthy, Erik Ingelsson, Nasa Sinnott-Armstrong, Manuel A Rivas

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PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility. by Gregory S Barsh, Gregory M Cooper, Gregory P Copenhaver, Greg Gibson, Mark I McCarthy, Hua Tang, Scott M Williams

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A Protein Domain and Family Based Approach to Rare Variant Association Analysis. by Tom G Richardson, Hashem A Shihab, Manuel A Rivas, Mark I McCarthy, Colin Campbell, Nicholas J Timpson, Tom R Gaunt

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Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes. by Delphine Fradin, Sophie Le Fur, Clémence Mille, Nadia Naoui, Chris Groves, Diana Zelenika, Mark I McCarthy, Mark Lathrop, Pierre Bougnères

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Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes. by Bahram Jafar-Mohammadi, Christopher J Groves, Katharine R Owen, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Anna L Gloyn

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Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers. by Anna L Gloyn, Johan H Faber, Daniel Malmodin, Gaya Thanabalasingham, Francis Lam, Per Magne Ueland, Mark I McCarthy, Katharine R Owen, Dorrit Baunsgaard

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Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells by Matthias Thurner, Liraz Shenhav, Agata Wesolowska-Andersen, Amanda J. Bennett, Amy Barrett, Anna L. Gloyn, Mark I. McCarthy, Nicola L. Beer, Shimon Efrat

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Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals by Agata Wesolowska-Andersen, Grace Zhuo Yu, Vibe Nylander, Fernando Abaitua, Matthias Thurner, Jason M Torres, Anubha Mahajan, Anna L Gloyn, Mark I McCarthy

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Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy by Zia Khan, Min Jung, Megan Crow, Rajat Mohindra, Vidya Maiya, Joshua S. Kaminker, David H. Hackos, G. Scott Chandler, Mark I. McCarthy, Tushar Bhangale

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Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells [version 2; peer review: 2 approved] by Jason M. Torres, Vibe Nylander, Han Sun, Martijn van de Bunt, Damien J. Downes, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn

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Burden of Diabetes and First Evidence for the Utility of HbA1c for Diagnosis and Detection of Diabetes in Urban Black South Africans: The Durban Diabetes Study. by Thomas R Hird, Fraser J Pirie, Tonya M Esterhuizen, Brian O'Leary, Mark I McCarthy, Elizabeth H Young, Manjinder S Sandhu, Ayesha A Motala

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Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data by Juan Fernández-Tajes, Kyle J. Gaulton, Martijn van de Bunt, Jason Torres, Matthias Thurner, Anubha Mahajan, Anna L. Gloyn, Kasper Lage, Mark I. McCarthy

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The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis. by Martijn van de Bunt, Kyle J Gaulton, Leopold Parts, Ignasi Moran, Paul R Johnson, Cecilia M Lindgren, Jorge Ferrer, Anna L Gloyn, Mark I McCarthy

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Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery. by Reedik Mägi, Sean Manning, Ahmed Yousseif, Andrea Pucci, Ferruccio Santini, Efthimia Karra, Giorgia Querci, Caterina Pelosini, Mark I McCarthy, Cecilia M Lindgren, Rachel L Batterham

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BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study. by Yvonne V Louwers, Nigel W Rayner, Blanca M Herrera, Lisette Stolk, Christopher J Groves, Thomas M Barber, Andre G Uitterlinden, Stephen Franks, Joop S E Laven, Mark I McCarthy

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Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. by Michael N Weedon, Mark I McCarthy, Graham Hitman, Mark Walker, Christopher J Groves, Eleftheria Zeggini, N William Rayner, Beverley Shields, Katharine R Owen, Andrew T Hattersley, Timothy M Frayling

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Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade by Zia Khan, Christian Hammer, Jonathan Carroll, Flavia Di Nucci, Sergio Ley Acosta, Vidya Maiya, Tushar Bhangale, Julie Hunkapiller, Ira Mellman, Matthew L. Albert, Mark I. McCarthy, G. Scott Chandler

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Common maternal and fetal genetic variants show expected polygenic effects on risk of small- or large-for-gestational-age (SGA or LGA), except in the smallest 3% of babies. by Robin N Beaumont, Sarah J Kotecha, Andrew R Wood, Bridget A Knight, Sylvain Sebert, Mark I McCarthy, Andrew T Hattersley, Marjo-Riitta Järvelin, Nicholas J Timpson, Rachel M Freathy, Sailesh Kotecha

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