Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes by Wenjing Yan, Yongwang Zhong, Xin Hu, Tuan Xu, Yinghua Zhang, Stephen Kales, Yanyan Qu, Daniel C. Talley, Bolormaa Baljinnyam, Christopher A. LeClair, Anton Simeonov, Brian M. Polster, Ruili Huang, Yihong Ye, Ganesha Rai, Mark J. Henderson, Dingyin Tao, Shengyun Fang

Get full text

Phenotype plasticity and altered sensitivity to chemotherapeutic agents in aggressive prostate cancer cells by Allan I. Paxson, Allan I. Paxson, Loren H. Chang, Jaime M. C. Gard, William L. Harryman, Colin S. Nelson, Stella B. Salmon, Kendra D. Marr, Kendra D. Marr, Leah M. Wachsmuth, Anita Ramanathan, Jing Ran, Abhijeet Kapoor, Juan J. Marugan, Mark J. Henderson, Tino W. Sanchez, Anne E. Cress, Anne E. Cress

Get full text

Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice by América Chandía-Cristi, Daniela A. Gutiérrez, Andrés E. Dulcey, Marcelo Lara, Lina Vargas, Yi-Han Lin, Pablo Jimenez-Muñoz, Gabriela Larenas, Xin Xu, Amy Wang, Ashley Owens, Christopher Dextras, YuChi Chen, Claudio Pinto, Tamara Marín, Hugo Almarza-Salazar, Keryma Acevedo, Gonzalo I. Cancino, Xin Hu, Patricio Rojas, Marc Ferrer, Noel Southall, Mark J. Henderson, Silvana Zanlungo, Juan J. Marugan, Alejandra Álvarez R

Get full text