QuPath Algorithm Accurately Identifies MLH1-Deficient Inflammatory Bowel Disease-Associated Colorectal Cancers in a Tissue Microarray by Ross J. Porter, Shahida Din, Peter Bankhead, Anca Oniscu, Mark J. Arends

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Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation by Guia Cerretelli, Ying Zhou, Mike F. Müller, David J. Adams, Mark J. Arends

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DNA mismatch repair and CD133-marked cancer stem cells in colorectal carcinoma by Phaik-Leng Cheah, Jing Li, Lai-Meng Looi, Kean-Hooi Teoh, Diana Bee-Lan Ong, Mark J. Arends

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PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate by Helen M. Wise, Adam Harris, Nisha Kriplani, Adam Schofield, Helen Caldwell, Mark J. Arends, Ian M. Overton, Nick R. Leslie

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RFWD3 modulates response to platinum chemotherapy and promotes cancer associated phenotypes in high grade serous ovarian cancer by Sarah J. Taylor, Sarah J. Taylor, Robert L. Hollis, Charlie Gourley, C. Simon Herrington, C. Simon Herrington, Simon P. Langdon, Mark J. Arends

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Improving the Diagnosis of Endometrial Hyperplasia Using Computerized Analysis and Immunohistochemical Biomarkers by Peter A. Sanderson, Peter A. Sanderson, Arantza Esnal-Zufiaurre, Mark J. Arends, C. Simon Herrington, Frances Collins, Alistair R. W. Williams, Philippa T. K. Saunders

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Towards a clinically-based common coordinate framework for the human gut cell atlas: the gut models by Albert Burger, Richard A. Baldock, David J. Adams, Shahida Din, Irene Papatheodorou, Michael Glinka, Bill Hill, Derek Houghton, Mehran Sharghi, Michael Wicks, Mark J. Arends

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Primordial germ cell DNA demethylation and development require DNA translesion synthesis by Pranay Shah, Ross Hill, Camille Dion, Stephen J. Clark, Abdulkadir Abakir, Jeroen Willems, Mark J. Arends, Juan I. Garaycoechea, Harry G. Leitch, Wolf Reik, Gerry P. Crossan

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Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations by Robert L. Hollis, Alison M. Meynert, Michael Churchman, Tzyvia Rye, Melanie Mackean, Fiona Nussey, Mark J. Arends, Andrew H. Sims, Colin A. Semple, C. Simon Herrington, Charlie Gourley

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Correction: Modeling Partial Monosomy for Human Chromosome 21q11.2-q21.1 Reveals Haploinsufficient Genes Influencing Behavior and Fat Deposition. by Anna M. Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K. White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W. Logan, Mark J. Arends, David J. Adams

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Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition. by Anna M Migdalska, Louise van der Weyden, Ozama Ismail, Jacqueline K White, Sanger Mouse Genetics Project, Gabriela Sánchez-Andrade, Darren W Logan, Mark J Arends, David J Adams

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pTDP‐43 aggregates accumulate in non‐central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis: a case series linking archival surgical biopsies with c... by Samuel B Pattle, Judi O'Shaughnessy, Owen Kantelberg, Olivia M Rifai, Judith Pate, Kristine Nellany, Nadine Hays, Mark J Arends, Mathew H Horrocks, Fergal M Waldron, Jenna M Gregory

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Gorham-Stout case report: a multi-omic analysis reveals recurrent fusions as new potential drivers of the disease by Marcos Yébenes Mayordomo, Sofian Al Shboul, Maria Gómez-Herranz, Asim Azfer, Alison Meynert, Donald Salter, Larry Hayward, Anca Oniscu, James T. Patton, Ted Hupp, Mark J. Arends, Javier Antonio Alfaro

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The Comparative Pathology Workbench: Interactive visual analytics for biomedical data by Michael N. Wicks, Michael Glinka, Bill Hill, Derek Houghton, Mehran Sharghi, Ingrid Ferreira, David Adams, Shahida Din, Irene Papatheodorou, Kathryn Kirkwood, Michael Cheeseman, Albert Burger, Richard A. Baldock, Mark J. Arends

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Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution by Nicole M. Sodir, Luca Pellegrinet, Roderik M. Kortlever, Tania Campos, Yong-Won Kwon, Shinseog Kim, Daniel Garcia, Alessandra Perfetto, Panayiotis Anastasiou, Lamorna Brown Swigart, Mark J. Arends, Trevor D. Littlewood, Gerard I. Evan

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Correction: Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa. by Chinyere K Okoro, Lars Barquist, Thomas R Connor, Simon R Harris, Simon Clare, Mark P Stevens, Mark J Arends, Christine Hale, Leanne Kane, Derek J Pickard, Jennifer Hill, Katherine Harcourt, Julian Parkhill, Gordon Dougan, Robert A Kingsley

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CRISPR activation screen in mice identifies novel membrane proteins enhancing pulmonary metastatic colonisation by Louise van der Weyden, Victoria Harle, Gemma Turner, Victoria Offord, Vivek Iyer, Alastair Droop, Agnieszka Swiatkowska, Roy Rabbie, Andrew D. Campbell, Owen J. Sansom, Mercedes Pardo, Jyoti S. Choudhary, Ingrid Ferreira, Mark Tullett, Mark J. Arends, Anneliese O. Speak, David J. Adams

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FBXO7 sensitivity of phenotypic traits elucidated by a hypomorphic allele. by Carmen Ballesteros Reviriego, Simon Clare, Mark J Arends, Emma L Cambridge, Agnieszka Swiatkowska, Susana Caetano, Bushra Abu-Helil, Leanne Kane, Katherine Harcourt, David A Goulding, Diane Gleeson, Edward Ryder, Brendan Doe, Jacqueline K White, Louise van der Weyden, Gordon Dougan, David J Adams, Anneliese O Speak

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MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance by Matthew J. Sale, Kathryn Balmanno, Jayeta Saxena, Eiko Ozono, Katarzyna Wojdyla, Rebecca E. McIntyre, Rebecca Gilley, Anna Woroniuk, Karen D. Howarth, Gareth Hughes, Jonathan R. Dry, Mark J. Arends, Pilar Caro, David Oxley, Susan Ashton, David J. Adams, Julio Saez-Rodriguez, Paul D. Smith, Simon J. Cook

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Characterization of the yehUT two-component regulatory system of Salmonella enterica Serovar Typhi and Typhimurium. by Vanessa K Wong, Derek J Pickard, Lars Barquist, Karthikeyan Sivaraman, Andrew J Page, Peter J Hart, Mark J Arends, Kathryn E Holt, Leanne Kane, Lynda F Mottram, Louise Ellison, Ruben Bautista, Chris J McGee, Sally J Kay, Thomas M Wileman, Linda J Kenney, Calman A MacLennan, Robert A Kingsley, Gordon Dougan

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