Mark L. Kahn

Mark L. Kahn is a cardiologist currently serving as the Edward S. Cooper, M.D./Norman Roosevelt and Elizabeth Meriwether McLure Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania. At Penn, Kahn additionally serves as Director of Center for Vascular Biology and Director of Molecular Cardiology.

Kahn received a bachelor of arts in Biology from Brown University in 1984 and a medical degree from Brown's Alpert Medical School in 1987.

In 2011, Kahn received a $6 million grant from the Leducq Foundation to investigate lymphatic vascular defects and their contribution to cardiovascular diseases. Kahn's laboratory researches the role of signaling pathways in cardiovascular development and function. In 2017, research published by the lab linked intestinal bacteria to the structure of brain blood vessel.

In 2004, Kahn was elected a member of the American Society for Clinical Investigation. Provided by Wikipedia
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  1. 1
    CCBE1 regulates the development and prevents the age-dependent regression of meningeal lymphatics

    CCBE1 regulates the development and prevents the age-dependent regression of meningeal lymphatics by Zsombor Ocskay, László Bálint, Carolin Christ, Mark L. Kahn, Zoltán Jakus

    Published 2024-01-01
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  2. 2
    A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors

    A rationale for blocking thromboinflammation in COVID-19 with Btk inhibitors by Phillip LR. Nicolson, John D. Welsh, Abhishek Chauhan, Mark R. Thomas, Mark L. Kahn, Steve P. Watson

    Published 2020-07-01
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  3. 3
    VEGFR3 is required for button junction formation in lymphatic vessels

    VEGFR3 is required for button junction formation in lymphatic vessels by Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan

    Published 2023-07-01
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  4. 4
    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development

    VE-cadherin enables trophoblast endovascular invasion and spiral artery remodeling during placental development by Derek C Sung, Xiaowen Chen, Mei Chen, Jisheng Yang, Susan Schultz, Apoorva Babu, Yitian Xu, Siqi Gao, TC Stevenson Keller IV, Patricia Mericko-Ishizuka, Michelle Lee, Ying Yang, Joshua P Scallan, Mark L Kahn

    Published 2022-04-01
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  5. 5
    Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1K/K Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth

    Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1K/K Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung... by Kitti Szoták-Ajtay, Kitti Szoták-Ajtay, Dániel Szõke, Dániel Szõke, Gábor Kovács, Gábor Kovács, Judit Andréka, Judit Andréka, Gábor B. Brenner, Zoltán Giricz, Josef Penninger, Josef Penninger, Mark L. Kahn, Zoltán Jakus, Zoltán Jakus

    Published 2020-03-01
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  6. 6
    Endothelial SARS-CoV-2 infection is not the underlying cause of COVID-19-associated vascular pathology in mice

    Endothelial SARS-CoV-2 infection is not the underlying cause of COVID-19-associated vascular pathology in mice by Siqi Gao, Alan T. Tang, Min Wang, David W. Buchholz, Brian Imbiakha, Jisheng Yang, Xiaowen Chen, Peter Hewins, Patricia Mericko-Ishizuka, N. Adrian Leu, Stephanie Sterling, Avery August, Kellie A. Jurado, Edward E. Morrisey, Edward E. Morrisey, Hector Aguilar-Carreno, Mark L. Kahn

    Published 2023-09-01
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  7. 7
    Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice

    Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice by Barbara D. Summers, Kihwan Kim, Cristina C. Clement, Zohaib Khan, Sangeetha Thangaswamy, Jacob McCright, Katharina Maisel, Sofia Zamora, Stephanie Quintero, Alexandra C. Racanelli, David Redmond, Jeanine D’Armiento, Jisheng Yang, Amy Kuang, Laurel Monticelli, Mark L. Kahn, Augustine M. K. Choi, Laura Santambrogio, Hasina Outtz Reed

    Published 2022-03-01
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  8. 8
    Transcriptomic signatures of individual cell types in cerebral cavernous malformation

    Transcriptomic signatures of individual cell types in cerebral cavernous malformation by Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Je Yeong Sone, Thomas Moore, Dorothy DeBiasse, Agnieszka Stadnik, Justine J. Lee, Robert Shenkar, Janne Koskimäki, Miguel A. Lopez-Ramirez, Douglas A. Marchuk, Mark H. Ginsberg, Mark L. Kahn, Changbin Shi, Issam A. Awad

    Published 2024-01-01
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  9. 9
    Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.

    Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection. by Alan T Tang, David W Buchholz, Katherine M Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A Jurado, Mingang Xu, Edward E Morrisey, Sarah E Millar, Hector C Aguilar, Mark L Kahn

    Published 2023-02-01
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  10. 10
    Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma

    Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma by Sean P. Polster, Anukriti Sharma, Ceylan Tanes, Alan T. Tang, Patricia Mericko, Ying Cao, Julián Carrión-Penagos, Romuald Girard, Janne Koskimäki, Dongdong Zhang, Agnieszka Stadnik, Sharbel G. Romanos, Seán B. Lyne, Robert Shenkar, Kimberly Yan, Cornelia Lee, Amy Akers, Leslie Morrison, Myranda Robinson, Atif Zafar, Kyle Bittinger, Helen Kim, Jack A. Gilbert, Mark L. Kahn, Le Shen, Issam A. Awad

    Published 2020-05-01
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  11. 11
    Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations

    Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations by Janne Koskimäki, Dongdong Zhang, Yan Li, Laleh Saadat, Thomas Moore, Rhonda Lightle, Sean P. Polster, Julián Carrión-Penagos, Seán B. Lyne, Hussein A. Zeineddine, Changbin Shi, Robert Shenkar, Sharbel Romanos, Kenneth Avner, Abhinav Srinath, Le Shen, Matthew R. Detter, Daniel Snellings, Ying Cao, Miguel A. Lopez-Ramirez, Gregory Fonseca, Alan T. Tang, Pieter Faber, Jorge Andrade, Mark Ginsberg, Mark L. Kahn, Douglas A. Marchuk, Romuald Girard, Issam A. Awad

    Published 2019-08-01
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  12. 12
    Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma

    Plasma metabolites with mechanistic and clinical links to the neurovascular disease cavernous angioma by Abhinav Srinath, Bingqing Xie, Ying Li, Je Yeong Sone, Sharbel Romanos, Chang Chen, Anukriti Sharma, Sean Polster, Pieter C. Dorrestein, Kelly C. Weldon, Dorothy DeBiasse, Thomas Moore, Rhonda Lightle, Janne Koskimäki, Dongdong Zhang, Agnieszka Stadnik, Kristina Piedad, Matthew Hagan, Abdallah Shkoukani, Julián Carrión-Penagos, Dehua Bi, Le Shen, Robert Shenkar, Yuan Ji, Ashley Sidebottom, Eric Pamer, Jack A. Gilbert, Mark L. Kahn, Mark D’Souza, Dinanath Sulakhe, Issam A. Awad, Romuald Girard

    Published 2023-03-01
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