Messina: a novel analysis tool to identify biologically relevant molecules in disease. by Mark Pinese, Christopher J Scarlett, James G Kench, Emily K Colvin, Davendra Segara, Susan M Henshall, Robert L Sutherland, Andrew V Biankin

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Identification of novel sarcoma risk genes using a two-stage genome wide DNA sequencing strategy in cancer cluster families and population case and control cohorts by Rachel M. Jones, Phillip E. Melton, Mark Pinese, Alexander J. Rea, Evan Ingley, Mandy L. Ballinger, International Sarcoma Kindred Study, David J. Wood, David M. Thomas, Eric K. Moses

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ClinSV: clinical grade structural and copy number variant detection from whole genome sequencing data by Andre E. Minoche, Ben Lundie, Greg B. Peters, Thomas Ohnesorg, Mark Pinese, David M. Thomas, Andreas Zankl, Tony Roscioli, Nicole Schonrock, Sarah Kummerfeld, Leslie Burnett, Marcel E. Dinger, Mark J. Cowley

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Recruitment and activation of pancreatic stellate cells from the bone marrow in pancreatic cancer: a model of tumor-host interaction. by Christopher J Scarlett, Emily K Colvin, Mark Pinese, David K Chang, Adrienne L Morey, Elizabeth A Musgrove, Marina Pajic, Minoti Apte, Susan M Henshall, Robert L Sutherland, James G Kench, Andrew V Biankin

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Adar3 Is Involved in Learning and Memory in Mice by Dessislava Mladenova, Dessislava Mladenova, Guy Barry, Guy Barry, Lyndsey M. Konen, Lyndsey M. Konen, Lyndsey M. Konen, Sandy S. Pineda, Sandy S. Pineda, Boris Guennewig, Boris Guennewig, Lotta Avesson, Raphael Zinn, Raphael Zinn, Raphael Zinn, Nicole Schonrock, Nicole Schonrock, Maina Bitar, Maina Bitar, Nicky Jonkhout, Nicky Jonkhout, Lauren Crumlish, Dominik C. Kaczorowski, Andrew Gong, Mark Pinese, Mark Pinese, Gloria R. Franco, Carl R. Walkley, Bryce Vissel, Bryce Vissel, Bryce Vissel, John S. Mattick, John S. Mattick

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Identification of functional networks of estrogen- and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer. by Elizabeth A Musgrove, C Marcelo Sergio, Sherene Loi, Claire K Inman, Luke R Anderson, M Chehani Alles, Mark Pinese, C Elizabeth Caldon, Judith Schütte, Margaret Gardiner-Garden, Christopher J Ormandy, Grant McArthur, Alison J Butt, Robert L Sutherland

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BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state. by Emma M Rath, Yuen Yee Cheng, Mark Pinese, Kadir H Sarun, Amanda L Hudson, Christopher Weir, Yiwei D Wang, Anders P Håkansson, Viive M Howell, Guo Jun Liu, Glen Reid, Robert B Knott, Anthony P Duff, W Bret Church

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Introme accurately predicts the impact of coding and noncoding variants on gene splicing, with clinical applications by Patricia J. Sullivan, Velimir Gayevskiy, Ryan L. Davis, Marie Wong, Chelsea Mayoh, Amali Mallawaarachchi, Yvonne Hort, Mark J. McCabe, Sarah Beecroft, Matilda R. Jackson, Peer Arts, Andrew Dubowsky, Nigel Laing, Marcel E. Dinger, Hamish S. Scott, Emily Oates, Mark Pinese, Mark J. Cowley

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Retinoid signaling in pancreatic cancer, injury and regeneration. by Emily K Colvin, Johana M Susanto, James G Kench, Vivienna N Ong, Amanda Mawson, Mark Pinese, David K Chang, Ilse Rooman, Sandra A O'Toole, Davendra Segara, Elizabeth A Musgrove, Robert L Sutherland, Minoti V Apte, Christopher J Scarlett, Andrew V Biankin

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Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial by Rebecca Daly, Kate Hetherington, Emily Hazell, Bethany R. Wadling, Vanessa Tyrrell, Katherine M. Tucker, Glenn M. Marshall, David S. Ziegler, Loretta M. S. Lau, Toby N. Trahair, Tracey A. O’Brien, Kiri Collins, Andrew J. Gifford, Michelle Haber, Mark Pinese, David Malkin, Mark J. Cowley, Jonathan Karpelowsky, Donna Drew, Chris Jacobs, Claire E. Wakefield

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qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles. by Sarah Song, Katia Nones, David Miller, Ivon Harliwong, Karin S Kassahn, Mark Pinese, Marina Pajic, Anthony J Gill, Amber L Johns, Matthew Anderson, Oliver Holmes, Conrad Leonard, Darrin Taylor, Scott Wood, Qinying Xu, Felicity Newell, Mark J Cowley, Jianmin Wu, Peter Wilson, Lynn Fink, Andrew V Biankin, Nic Waddell, Sean M Grimmond, John V Pearson

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Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnos... by Yuyan Chen, Mark Pinese, Claire Wakefield, Frank Alvaro, Katherine Tucker, Tracey A O’Brien, Vanessa J Tyrrell, Judy Kirk, Kate Hetherington, Eliza Courtney, Kristine Barlow-Stewart, Noemi Auxiliadora Fuentes Bolanos, Bhavna Padhye, Macabe Daley, Jacqueline Hunter, Meera Warby, Sarah Josephi-Taylor, Marie Wong-Erasmus, Paulette Barahona, Pamela Ajuyah, Ann-Kristin Altekoester, Loretta M S Lau, Dianne Sylvester, Luciano Dalla Pozza

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Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer by James R.W. Conway, Sean C. Warren, David Herrmann, Kendelle J. Murphy, Aurélie S. Cazet, Claire Vennin, Robert F. Shearer, Monica J. Killen, Astrid Magenau, Pauline Mélénec, Mark Pinese, Max Nobis, Anaiis Zaratzian, Alice Boulghourjian, Andrew M. Da Silva, Gonzalo del Monte-Nieto, Arne S.A. Adam, Richard P. Harvey, Jody J. Haigh, Yingxiao Wang, David R. Croucher, Owen J. Sansom, Marina Pajic, C. Elizabeth Caldon, Jennifer P. Morton, Paul Timpson

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Lost in translation: returning germline genetic results in genome-scale cancer research by Amber L. Johns, Skye H. McKay, Jeremy L. Humphris, Mark Pinese, Lorraine A. Chantrill, R. Scott Mead, Katherine Tucker, Lesley Andrews, Annabel Goodwin, Conrad Leonard, Hilda A. High, Katia Nones, Ann-Marie Patch, Neil D. Merrett, Nick Pavlakis, Karin S. Kassahn, Jaswinder S. Samra, David K. Miller, David K. Chang, Marina Pajic, Australian Pancreatic Cancer Genome Initiative, John V. Pearson, Sean M. Grimmond, Nicola Waddell, Nikolajs Zeps, Anthony J. Gill, Andrew V. Biankin

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Somatic point mutation calling in low cellularity tumors. by Karin S Kassahn, Oliver Holmes, Katia Nones, Ann-Marie Patch, David K Miller, Angelika N Christ, Ivon Harliwong, Timothy J Bruxner, Qinying Xu, Matthew Anderson, Scott Wood, Conrad Leonard, Darrin Taylor, Felicity Newell, Sarah Song, Senel Idrisoglu, Craig Nourse, Ehsan Nourbakhsh, Suzanne Manning, Shivangi Wani, Anita Steptoe, Marina Pajic, Mark J Cowley, Mark Pinese, David K Chang, Anthony J Gill, Amber L Johns, Jianmin Wu, Peter J Wilson, Lynn Fink, Andrew V Biankin, Nicola Waddell, Sean M Grimmond, John V Pearson

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CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan by Claire Vennin, Pauline Mélénec, Romain Rouet, Max Nobis, Aurélie S. Cazet, Kendelle J. Murphy, David Herrmann, Daniel A. Reed, Morghan C. Lucas, Sean C. Warren, Zehra Elgundi, Mark Pinese, Gabriella Kalna, Daniel Roden, Monisha Samuel, Anaiis Zaratzian, Shane T. Grey, Andrew Da Silva, Wilfred Leung, Australian Pancreatic Genome Initiative (APGI), Suresh Mathivanan, Yingxiao Wang, Anthony W. Braithwaite, Daniel Christ, Ales Benda, Ashleigh Parkin, Phoebe A. Phillips, John M. Whitelock, Anthony J. Gill, Owen J. Sansom, David R. Croucher, Benjamin L. Parker, Marina Pajic, Jennifer P. Morton, Thomas R. Cox, Paul Timpson

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The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly by Mark Pinese, Paul Lacaze, Emma M. Rath, Andrew Stone, Marie-Jo Brion, Adam Ameur, Sini Nagpal, Clare Puttick, Shane Husson, Dmitry Degrave, Tina Navin Cristina, Vivian F. S. Kahl, Aaron L. Statham, Robyn L. Woods, John J. McNeil, Moeen Riaz, Margo Barr, Mark R. Nelson, Christopher M. Reid, Anne M. Murray, Raj C. Shah, Rory Wolfe, Joshua R. Atkins, Chantel Fitzsimmons, Heath M. Cairns, Melissa J. Green, Vaughan J. Carr, Mark J. Cowley, Hilda A. Pickett, Paul A. James, Joseph E. Powell, Warren Kaplan, Greg Gibson, Ulf Gyllensten, Murray J. Cairns, Martin McNamara, Marcel E. Dinger, David M. Thomas

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In vitro and in vivo drug screens of tumor cells identify novel therapies for high‐risk child cancer by Loretta M S Lau, Chelsea Mayoh, Jinhan Xie, Paulette Barahona, Karen L MacKenzie, Marie Wong, Alvin Kamili, Maria Tsoli, Tim W Failes, Amit Kumar, Emily V A Mould, Andrew Gifford, Shu‐Oi Chow, Mark Pinese, Jamie I Fletcher, Greg M Arndt, Dong‐Anh Khuong‐Quang, Carol Wadham, Daniel Batey, Georgina Eden, Peter Trebilcock, Swapna Joshi, Stephanie Alfred, Anjana Gopalakrishnan, Aaminah Khan, Dylan Grebert Wade, Patrick A Strong, Elodie Manouvrier, Lisa T Morgan, Miriam Span, Jin Yi Lim, Roxanne Cadiz, Caitlin Ung, David M Thomas, Katherine M Tucker, Meera Warby, Geoffrey B McCowage, Luciano Dalla‐Pozza, Jennifer A Byrne, Federica Saletta, Andrew Fellowes, Stephen B Fox, Murray D Norris, Vanessa Tyrrell, Toby N Trahair, Richard B Lock, Mark J Cowley, Paul G Ekert, Michelle Haber, David S Ziegler, Glenn M Marshall

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