Molecules that cause or prevent Parkinson's disease. by Mark R Cookson

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Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions by Elisa Greggio, Mark R Cookson

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Generation of gene-corrected isogenic controls from Parkinson's disease patient iPSC lines carrying the pathogenic SNCA p.A53T variant by Nikita Kozhushko, Aleksandra Beilina, Mark R. Cookson

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Glial phagocytic clearance in Parkinson’s disease by Marie-Eve Tremblay, Mark R. Cookson, Laura Civiero

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The role of monogenic genes in idiopathic Parkinson’s disease by Xylena Reed, Sara Bandrés-Ciga, Cornelis Blauwendraat, Mark R. Cookson

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Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2) by Aleksandra Beylina, Rebekah G. Langston, Dorien Rosen, Xylena Reed, Mark R. Cookson

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Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment by Jillian H. Kluss, Luis Bonet-Ponce, Patrick A. Lewis, Mark R. Cookson

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Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation by Melissa Conti Mazza, Alexandra Beilina, Dorien A. Roosen, David Hauser, Mark R. Cookson

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Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. by David N Hauser, Allissa A Dillman, Jinhui Ding, Yan Li, Mark R Cookson

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Preclinical modeling of chronic inhibition of the Parkinson’s disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo by Jillian H. Kluss, Melissa Conti Mazza, Yan Li, Claudia Manzoni, Patrick A. Lewis, Mark R. Cookson, Adamantios Mamais

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Structure and regulation of full-length human leucine-rich repeat kinase 1 by Riley D. Metcalfe, Juliana A. Martinez Fiesco, Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson, Ping Zhang

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Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched by Xylena Reed, Melanie M. Cobb, Gaia Skinbinski, Dorien Roosen, Alice Kaganovich, Jinhui Ding, Steve Finkbeiner, Mark R. Cookson

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The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. by Azad Kumar, Elisa Greggio, Alexandra Beilina, Alice Kaganovich, Diane Chan, Jean-Marc Taymans, Benjamin Wolozin, Mark R Cookson

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LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding. by Jean-Marc Taymans, Renée Vancraenenbroeck, Petri Ollikainen, Alexandra Beilina, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Mark R Cookson

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Variant biomarker discovery using mass spectrometry-based proteogenomics by Luke Reilly, Sahba Seddighi, Andrew B. Singleton, Andrew B. Singleton, Mark R. Cookson, Michael E. Ward, Yue A. Qi

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Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4 by Isabella Russo, Giulietta Di Benedetto, Alice Kaganovich, Jinhui Ding, Daniela Mercatelli, Michele Morari, Mark R. Cookson, Luigi Bubacco, Elisa Greggio

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Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging by Lilach Soreq, Jamie Rose, Eyal Soreq, John Hardy, Daniah Trabzuni, Mark R. Cookson, Colin Smith, Mina Ryten, Rickie Patani, Jernej Ule

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. by Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle

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Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. by Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howell

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Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils by Isabella Russo, Alice Kaganovich, Jinhui Ding, Natalie Landeck, Adamantios Mamais, Tatiana Varanita, Alice Biosa, Isabella Tessari, Luigi Bubacco, Elisa Greggio, Mark R. Cookson

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