Zobrazuji výsledky 1 - 20 z 46 pro vyhledávání 'Mark R. Cookson', doba hledání: 0,06 s. Upřesnit hledání
  1. 1
    Molecules that cause or prevent Parkinson's disease.

    Molecules that cause or prevent Parkinson's disease. Autor Mark R Cookson

    Vydáno 2004-11-01
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  2. 2
    Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions

    Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions Autor Elisa Greggio, Mark R Cookson

    Vydáno 2009-03-01
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  3. 3
    Generation of gene-corrected isogenic controls from Parkinson's disease patient iPSC lines carrying the pathogenic SNCA p.A53T variant

    Generation of gene-corrected isogenic controls from Parkinson's disease patient iPSC lines carrying the pathogenic SNCA p.A53T variant Autor Nikita Kozhushko, Aleksandra Beilina, Mark R. Cookson

    Vydáno 2023-06-01
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  4. 4
    Glial phagocytic clearance in Parkinson’s disease

    Glial phagocytic clearance in Parkinson’s disease Autor Marie-Eve Tremblay, Mark R. Cookson, Laura Civiero

    Vydáno 2019-04-01
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  5. 5
    The role of monogenic genes in idiopathic Parkinson’s disease

    The role of monogenic genes in idiopathic Parkinson’s disease Autor Xylena Reed, Sara Bandrés-Ciga, Cornelis Blauwendraat, Mark R. Cookson

    Vydáno 2019-04-01
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  6. 6
    Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2)

    Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2) Autor Aleksandra Beylina, Rebekah G. Langston, Dorien Rosen, Xylena Reed, Mark R. Cookson

    Vydáno 2021-05-01
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  7. 7
    Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment

    Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment Autor Jillian H. Kluss, Luis Bonet-Ponce, Patrick A. Lewis, Mark R. Cookson

    Vydáno 2022-08-01
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  8. 8
    Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation

    Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation Autor Melissa Conti Mazza, Alexandra Beilina, Dorien A. Roosen, David Hauser, Mark R. Cookson

    Vydáno 2021-08-01
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  9. 9
    Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain.

    Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. Autor David N Hauser, Allissa A Dillman, Jinhui Ding, Yan Li, Mark R Cookson

    Vydáno 2014-01-01
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  10. 10
    Preclinical modeling of chronic inhibition of the Parkinson’s disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo

    Preclinical modeling of chronic inhibition of the Parkinson’s disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo Autor Jillian H. Kluss, Melissa Conti Mazza, Yan Li, Claudia Manzoni, Patrick A. Lewis, Mark R. Cookson, Adamantios Mamais

    Vydáno 2021-03-01
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  11. 11
    Structure and regulation of full-length human leucine-rich repeat kinase 1

    Structure and regulation of full-length human leucine-rich repeat kinase 1 Autor Riley D. Metcalfe, Juliana A. Martinez Fiesco, Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson, Ping Zhang

    Vydáno 2023-08-01
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  12. 12
    Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched

    Transcriptional signatures in iPSC-derived neurons are reproducible across labs when differentiation protocols are closely matched Autor Xylena Reed, Melanie M. Cobb, Gaia Skinbinski, Dorien Roosen, Alice Kaganovich, Jinhui Ding, Steve Finkbeiner, Mark R. Cookson

    Vydáno 2021-10-01
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  13. 13
    The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation.

    The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. Autor Azad Kumar, Elisa Greggio, Alexandra Beilina, Alice Kaganovich, Diane Chan, Jean-Marc Taymans, Benjamin Wolozin, Mark R Cookson

    Vydáno 2010-01-01
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  14. 14
    LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding.

    LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding. Autor Jean-Marc Taymans, Renée Vancraenenbroeck, Petri Ollikainen, Alexandra Beilina, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Mark R Cookson

    Vydáno 2011-01-01
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  15. 15
    Variant biomarker discovery using mass spectrometry-based proteogenomics

    Variant biomarker discovery using mass spectrometry-based proteogenomics Autor Luke Reilly, Sahba Seddighi, Andrew B. Singleton, Andrew B. Singleton, Mark R. Cookson, Michael E. Ward, Yue A. Qi

    Vydáno 2023-04-01
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  16. 16
    Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4

    Leucine-rich repeat kinase 2 controls protein kinase A activation state through phosphodiesterase 4 Autor Isabella Russo, Giulietta Di Benedetto, Alice Kaganovich, Jinhui Ding, Daniela Mercatelli, Michele Morari, Mark R. Cookson, Luigi Bubacco, Elisa Greggio

    Vydáno 2018-10-01
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  17. 17
    Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

    Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging Autor Lilach Soreq, Jamie Rose, Eyal Soreq, John Hardy, Daniah Trabzuni, Mark R. Cookson, Colin Smith, Mina Ryten, Rickie Patani, Jernej Ule

    Vydáno 2017-01-01
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  18. 18
    PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

    PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. Autor Derek P Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A Gautier, Jie Shen, Mark R Cookson, Richard J Youle

    Vydáno 2010-01-01
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  19. 19
    Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice.

    Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. Autor Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howell

    Vydáno 2012-01-01
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  20. 20
    Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

    Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils Autor Isabella Russo, Alice Kaganovich, Jinhui Ding, Natalie Landeck, Adamantios Mamais, Tatiana Varanita, Alice Biosa, Isabella Tessari, Luigi Bubacco, Elisa Greggio, Mark R. Cookson

    Vydáno 2019-09-01
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