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Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration by Stefan Gerhardy, Mark Ultsch, Wanjian Tang, Evan Green, Jeffrey K. Holden, Wei Li, Alberto Estevez, Chris Arthur, Irene Tom, Alexis Rohou, Daniel Kirchhofer
Published 2022-09-01
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Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif by Mark Ultsch, Michael J. Holliday, Stefan Gerhardy, Paul Moran, Suzie J. Scales, Nidhi Gupta, Francesca Oltrabella, Cecilia Chiu, Wayne Fairbrother, Charles Eigenbrot, Daniel Kirchhofer
Published 2021-07-01
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