Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants? by Philip Mwimanzi, Tristan J. Markle, Mark A. Brockman, Takamasa Ueno

Get full text

19 HIV-1 Nef enhances viral reactivation and downregulates HLA class I: a dual role in modulating immune-mediated clearance of reservoirs by XiaomeiT Kuang, Steven Jin, TristanM Markle, MarkA Brockman

Get full text

Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site MHgb and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa. by Manjeetha Jaggernath, Rumallen Naicker, Savathree Madurai, Mark A Brockman, Thumbi Ndung'u, Huub C Gelderblom

Get full text

Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors by Gisele Umviligihozo, Jaclyn K. Mann, Steven W. Jin, Francis M. Mwimanzi, Hua-Shiuan A. Hsieh, Hanwei Sudderuddin, Guinevere Q. Lee, Helen Byakwaga, Helen Byakwaga, Conrad Muzoora, Peter W. Hunt, Jeff N. Martin, Jessica E. Haberer, Jessica E. Haberer, Etienne Karita, Susan Allen, Eric Hunter, Eric Hunter, Zabrina L. Brumme, Zabrina L. Brumme, Mark A. Brockman, Mark A. Brockman, Mark A. Brockman

Get full text

Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products by Khumoekae Richard, David E. Williams, E. Dilip de Silva, Mark A. Brockman, Zabrina L. Brumme, Raymond J. Andersen, Ian Tietjen

Get full text

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences by Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D. Walker, Yong Xiong, Zabrina L. Brumme, Mark A. Brockman, Takamasa Ueno

Get full text

HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity by Delon Naicker, Nelson Sonela, Steven W. Jin, Takalani Mulaudzi, Doty Ojwach, Tarylee Reddy, Mark A. Brockman, Zabrina L. Brumme, Thumbi Ndung’u, Jaclyn K. Mann

Get full text

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity by Steven W. Jin, Nirmin Alsahafi, Xiaomei T. Kuang, Shayda A. Swann, Mako Toyoda, Heinrich Göttlinger, Bruce D. Walker, Takamasa Ueno, Andrés Finzi, Zabrina L. Brumme, Mark A. Brockman

Get full text

Serial infection with SARS-CoV-2 Omicron BA.1 and BA.2 following three-dose COVID-19 vaccination by Hope R. Lapointe, Francis Mwimanzi, Peter K. Cheung, Peter K. Cheung, Yurou Sang, Fatima Yaseen, Rebecca Kalikawe, Sneha Datwani, Rachel Waterworth, Gisele Umviligihozo, Siobhan Ennis, Landon Young, Winnie Dong, Don Kirkby, Laura Burns, Victor Leung, Victor Leung, Victor Leung, Daniel T. Holmes, Daniel T. Holmes, Mari L. DeMarco, Mari L. DeMarco, Janet Simons, Janet Simons, Nancy Matic, Nancy Matic, Nancy Matic, Julio S.G. Montaner, Julio S.G. Montaner, Chanson J. Brumme, Chanson J. Brumme, Natalie Prystajecky, Natalie Prystajecky, Masahiro Niikura, Christopher F. Lowe, Christopher F. Lowe, Christopher F. Lowe, Marc G. Romney, Marc G. Romney, Marc G. Romney, Mark A. Brockman, Mark A. Brockman, Mark A. Brockman, Zabrina L. Brumme, Zabrina L. Brumme

Get full text

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5. by Steven W Jin, Francis M Mwimanzi, Jaclyn K Mann, Mwebesa Bosco Bwana, Guinevere Q Lee, Chanson J Brumme, Peter W Hunt, Jeff N Martin, David R Bangsberg, Thumbi Ndung'u, Zabrina L Brumme, Mark A Brockman

Get full text

Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors. by Ian Tietjen, Fidele Ntie-Kang, Philip Mwimanzi, Pascal Amoa Onguéné, Margaret A Scull, Thomas Oyebode Idowu, Abiodun Oguntuga Ogundaini, Luc Mbaze Meva'a, Berhanu M Abegaz, Charles M Rice, Kerstin Andrae-Marobela, Mark A Brockman, Zabrina L Brumme, David Fedida

Get full text

HIV Proviral Burden, Genetic Diversity, and Dynamics in Viremic Controllers Who Subsequently Initiated Suppressive Antiretroviral Therapy by F. Harrison Omondi, Hanwei Sudderuddin, Aniqa Shahid, Natalie N. Kinloch, Bradley R. Jones, Rachel L. Miller, Olivia Tsai, Daniel MacMillan, Alicja Trocha, Mark A. Brockman, Chanson J. Brumme, Jeffrey B. Joy, Richard Liang, Bruce D. Walker, Zabrina L. Brumme

Get full text

HIV reservoirs are dominated by genetically younger and clonally enriched proviruses by Natalie N. Kinloch, Aniqa Shahid, Winnie Dong, Don Kirkby, Bradley R. Jones, Charlotte J. Beelen, Daniel MacMillan, Guinevere Q. Lee, Talia M. Mota, Hanwei Sudderuddin, Evan Barad, Marianne Harris, Chanson J. Brumme, R. Brad Jones, Mark A. Brockman, Jeffrey B. Joy, Zabrina L. Brumme

Get full text

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation by Subha Dahal, Ran Cheng, Peter K. Cheung, Terek Been, Ramy Malty, Melissa Geng, Sarah Manianis, Lulzim Shkreta, Shahrazad Jahanshahi, Johanne Toutant, Rose Chan, Sean Park, Mark A. Brockman, Mohan Babu, Samira Mubareka, Karen Mossman, Arinjay Banerjee, Scott Gray-Owen, Martha Brown, Walid A. Houry, Benoit Chabot, David Grierson, Alan Cochrane

Get full text

Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations. by Kuan-Hsiang Gary Huang, Dominique Goedhals, Jonathan M Carlson, Mark A Brockman, Swati Mishra, Zabrina L Brumme, Stephen Hickling, Christopher S W Tang, Toshiyuki Miura, Chris Seebregts, David Heckerman, Thumbi Ndung'u, Bruce Walker, Paul Klenerman, Dewald Steyn, Philip Goulder, Rodney Phillips, Bloemfontein-Oxford Collaborative Group, Cloete van Vuuren, John Frater

Get full text

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins. by Zabrina L Brumme, Mina John, Jonathan M Carlson, Chanson J Brumme, Dennison Chan, Mark A Brockman, Luke C Swenson, Iris Tao, Sharon Szeto, Pamela Rosato, Jennifer Sela, Carl M Kadie, Nicole Frahm, Christian Brander, David W Haas, Sharon A Riddler, Richard Haubrich, Bruce D Walker, P Richard Harrigan, David Heckerman, Simon Mallal

Get full text

HLA-C downregulation by HIV-1 adapts to host HLA genotype. by Nathaniel D Bachtel, Gisele Umviligihozo, Suzanne Pickering, Talia M Mota, Hua Liang, Gregory Q Del Prete, Pramita Chatterjee, Guinevere Q Lee, Rasmi Thomas, Mark A Brockman, Stuart Neil, Mary Carrington, Bosco Bwana, David R Bangsberg, Jeffrey N Martin, Esper G Kallas, Camila S Donini, Natalia B Cerqueira, Una T O'Doherty, Beatrice H Hahn, R Brad Jones, Zabrina L Brumme, Douglas F Nixon, Richard Apps

Get full text

Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy by Zabrina L. Brumme, Francis Mwimanzi, Hope R. Lapointe, Peter K. Cheung, Yurou Sang, Maggie C. Duncan, Fatima Yaseen, Olga Agafitei, Siobhan Ennis, Kurtis Ng, Simran Basra, Li Yi Lim, Rebecca Kalikawe, Sarah Speckmaier, Nadia Moran-Garcia, Landon Young, Hesham Ali, Bruce Ganase, Gisele Umviligihozo, F. Harrison Omondi, Kieran Atkinson, Hanwei Sudderuddin, Junine Toy, Paul Sereda, Laura Burns, Cecilia T. Costiniuk, Curtis Cooper, Aslam H. Anis, Victor Leung, Daniel Holmes, Mari L. DeMarco, Janet Simons, Malcolm Hedgcock, Marc G. Romney, Rolando Barrios, Silvia Guillemi, Chanson J. Brumme, Ralph Pantophlet, Julio S. G. Montaner, Masahiro Niikura, Marianne Harris, Mark Hull, Mark A. Brockman

Get full text