Fatigue and muscle atrophy in a mouse model of myasthenia gravis is paralleled by loss of sarcolemmal nNOS. by Sarina Meinen, Shuo Lin, Markus A Rüegg, Anna Rostedt Punga

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Editorial: Current Insights Into LAMA2 Disease by Stefano C. Previtali, Ronald D. Cohn, Ronald D. Cohn, Markus A. Ruegg

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mTORC2 affects the maintenance of the muscle stem cell pool by Nathalie Rion, Perrine Castets, Shuo Lin, Leonie Enderle, Judith R. Reinhard, Markus A. Rüegg

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Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9 by Marco Thürkauf, Shuo Lin, Filippo Oliveri, Dirk Grimm, Randall J. Platt, Markus A. Rüegg

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Injection of a soluble fragment of neural agrin (NT-1654) considerably improves the muscle pathology caused by the disassembly of the neuromuscular junction. by Stefan Hettwer, Shuo Lin, Stefan Kucsera, Monika Haubitz, Filippo Oliveri, Ruggero G Fariello, Markus A Ruegg, Jan W Vrijbloed

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mTORC1 signalling is not essential for the maintenance of muscle mass and function in adult sedentary mice by Alexander S. Ham, Kathrin Chojnowska, Lionel A. Tintignac, Shuo Lin, Alexander Schmidt, Daniel J. Ham, Michael Sinnreich, Markus A. Rüegg

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Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia by Anastasiya Börsch, Daniel J. Ham, Nitish Mittal, Lionel A. Tintignac, Eugenia Migliavacca, Jérôme N. Feige, Markus A. Rüegg, Mihaela Zavolan

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Increasing Agrin Function Antagonizes Muscle Atrophy and Motor Impairment in Spinal Muscular Atrophy by Marina Boido, Elena De Amicis, Valeria Valsecchi, Marco Trevisan, Ugo Ala, Markus A. Ruegg, Stefan Hettwer, Alessandro Vercelli, Alessandro Vercelli

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WNT7B promotes bone formation in part through mTORC1. by Jianquan Chen, Xiaolin Tu, Emel Esen, Kyu Sang Joeng, Congxin Lin, Jeffrey M Arbeit, Markus A Rüegg, Michael N Hall, Liang Ma, Fanxin Long

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Raptor levels are critical for β-cell adaptation to a high-fat diet in male mice by Manuel Blandino-Rosano, Ruy Andrade Louzada, Joao Pedro Werneck-De-Castro, Camila Lubaczeuski, Joana Almaça, Markus A. Rüegg, Michael N. Hall, Gil Leibowitz, Ernesto Bernal-Mizrachi

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Dual roles of mTORC1-dependent activation of the ubiquitin-proteasome system in muscle proteostasis by Marco S. Kaiser, Giulia Milan, Daniel J. Ham, Shuo Lin, Filippo Oliveri, Kathrin Chojnowska, Lionel A. Tintignac, Nitish Mittal, Christian E. Zimmerli, David J. Glass, Mihaela Zavolan, Markus A. Rüegg

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Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner by Lianjun Zhang, Benjamin O. Tschumi, Isabel C. Lopez-Mejia, Susanne G. Oberle, Marten Meyer, Guerric Samson, Markus A. Rüegg, Michael N. Hall, Lluis Fajas, Dietmar Zehn, Jean-Pierre Mach, Alena Donda, Pedro Romero

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Loss of mTORC1 signalling impairs β-cell homeostasis and insulin processing by Manuel Blandino-Rosano, Rebecca Barbaresso, Margarita Jimenez-Palomares, Nadejda Bozadjieva, Joao Pedro Werneck-de-Castro, Masayuki Hatanaka, Raghavendra G. Mirmira, Nahum Sonenberg, Ming Liu, Markus A. Rüegg, Michael N. Hall, Ernesto Bernal-Mizrachi

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Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle by Daniel J. Ham, Anastasiya Börsch, Kathrin Chojnowska, Shuo Lin, Aurel B. Leuchtman, Alexander S. Ham, Marco Thürkauf, Julien Delezie, Regula Furrer, Dominik Burri, Michael Sinnreich, Christoph Handschin, Lionel A. Tintignac, Mihaela Zavolan, Nitish Mittal, Markus A. Rüegg

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mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4 by Perrine Castets, Nathalie Rion, Marine Théodore, Denis Falcetta, Shuo Lin, Markus Reischl, Franziska Wild, Laurent Guérard, Christopher Eickhorst, Marielle Brockhoff, Maitea Guridi, Chikwendu Ibebunjo, Joseph Cruz, Michael Sinnreich, Rüdiger Rudolf, David J. Glass, Markus A. Rüegg

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Author Correction: Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle by Daniel J. Ham, Anastasiya Börsch, Kathrin Chojnowska, Shuo Lin, Aurel B. Leuchtmann, Alexander S. Ham, Marco Thürkauf, Julien Delezie, Regula Furrer, Dominik Burri, Michael Sinnreich, Christoph Handschin, Lionel A. Tintignac, Mihaela Zavolan, Nitish Mittal, Markus A. Rüegg

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mTORC1 Controls PNS Myelination along the mTORC1-RXRγ-SREBP-Lipid Biosynthesis Axis in Schwann Cells by Camilla Norrmén, Gianluca Figlia, Frédéric Lebrun-Julien, Jorge A. Pereira, Martin Trötzmüller, Harald C. Köfeler, Ville Rantanen, Carsten Wessig, Anne-Lieke F. van Deijk, August B. Smit, Mark H.G. Verheijen, Markus A. Rüegg, Michael N. Hall, Ueli Suter

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The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia by Daniel J. Ham, Anastasiya Börsch, Shuo Lin, Marco Thürkauf, Martin Weihrauch, Judith R. Reinhard, Julien Delezie, Fabienne Battilana, Xueyong Wang, Marco S. Kaiser, Maitea Guridi, Michael Sinnreich, Mark M. Rich, Nitish Mittal, Lionel A. Tintignac, Christoph Handschin, Mihaela Zavolan, Markus A. Rüegg

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mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3 by Maximilian Kleinert, Benjamin L. Parker, Rima Chaudhuri, Daniel J. Fazakerley, Annette Serup, Kristen C. Thomas, James R. Krycer, Lykke Sylow, Andreas M. Fritzen, Nolan J. Hoffman, Jacob Jeppesen, Peter Schjerling, Markus A. Ruegg, Bente Kiens, David E. James, Erik A. Richter

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