ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia by Thomas Ernst, Jana Hoffmann, Philipp Erben, Benjamin Hanfstein, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus, Martin C. Müller

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The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia by Thoralf Lange, Thomas Ernst, Franz X. Gruber, Jacqueline Maier, Michael Cross, Martin C. Müller, Dietger Niederwieser, Andreas Hochhaus, Markus Pfirrmann

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Dynamics of mutant BCR-ABL-positive clones after cessation of tyrosine kinase inhibitor therapy by Benjamin Hanfstein, Martin C. Müller, Sebastian Kreil, Thomas Ernst, Thomas Schenk, Christian Lorentz, Uwe Schwindel, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus

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Response dynamics of pediatric patients with chronic myeloid leukemia on imatinib therapy by Rick Proschmann, Christoph Baldow, Tino Rothe, Meinolf Suttorp, Christian Thiede, Josephine T. Tauer, Martin C. Müller, Andreas Hochhaus, Ingo Roeder, Ingmar Glauche

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Dynamics of cytogenetic aberrations in Philadelphia chromosome positive and negative hematopoiesis during dasatinib therapy of chronic myeloid leukemia patients after imatinib fail... by Alice Fabarius, Claudia Haferlach, Martin C. Müller, Philipp Erben, Tanja Lahaye, Michelle Giehl, Oliver Frank, Wolfgang Seifarth, Rüdiger Hehlmann, Andreas Hochhaus

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Dynamics of BCR-ABL mutated clones prior to hematologic or cytogenetic resistance to imatinib by Thomas Ernst, Philipp Erben, Martin C. Müller, Peter Paschka, Thomas Schenk, Jana Hoffmann, Sebastian Kreil, Paul La Rosée, Rüdiger Hehlmann, Andreas Hochhaus

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A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy... by Thomas Ernst, Franz X. Gruber, Oliver Pelz-Ackermann, Jacqueline Maier, Markus Pfirrmann, Martin C. Müller, Ingvild Mikkola, Kimmo Porkka, Dietger Niederwieser, Andreas Hochhaus, Thoralf Lange

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Screening for diverse PDGFRA or PDGFRB fusion genes is facilitated by generic quantitative reverse transcriptase polymerase chain reaction analysis by Philipp Erben, Darko Gosenca, Martin C. Müller, Jelena Reinhard, Joannah Score, Francesco del Valle, Christoph Walz, Jürgen Mix, Georgia Metzgeroth, Thomas Ernst, Claudia Haferlach, Nicholas C.P. Cross, Andreas Hochhaus, Andreas Reiter

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Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase ch... by Neil P. Shah, Dong-Wook Kim, Hagop Kantarjian, Philippe Rousselot, Pedro Enrique Dorlhiac Llacer, Alicia Enrico, Jorge Vela-Ojeda, Richard T. Silver, Hanna Jean Khoury, Martin C. Müller, Alexandre Lambert, Yousif Matloub, Andreas Hochhaus

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An international study to standardize the detection and quantitation of BCR-ABL transcripts from stabilized peripheral blood preparations by quantitative RT-PCR by Martin C. Müller, Giuseppe Saglio, Feng Lin, Heike Pfeifer, Richard D. Press, Raymond R. Tubbs, Peter Paschka, Enrico Gottardi, Steven G. O’Brien, Oliver G. Ottmann, Hubertus Stockinger, Lothar Wieczorek, Kirsten Merx, Heiko König, Uwe Schwindel, Rüdiger Hehlmann, Andreas Hochhaus

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The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1 - CD44 axis by Parimala Sonika Godavarthy, Rahul Kumar, Stefanie C. Herkt, Raquel S. Pereira, Nina Hayduk, Eva S. Weissenberger, Djamel Aggoune, Yosif Manavski, Tina Lucas, Kuan-Ting Pan, Jenna M. Voutsinas, Qian Wu, Martin C. Müller, Susanne Saussele, Thomas Oellerich, Vivian G. Oehler, Joern Lausen, Daniela S. Krause

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Distinct characteristics of e13a2 versus e14a2 BCR-ABL1 driven chronic myeloid leukemia under first-line therapy with imatinib by Benjamin Hanfstein, Michael Lauseker, Rüdiger Hehlmann, Susanne Saussele, Philipp Erben, Christian Dietz, Alice Fabarius, Ulrike Proetel, Susanne Schnittger, Claudia Haferlach, Stefan W. Krause, Jörg Schubert, Hermann Einsele, Mathias Hänel, Jolanta Dengler, Christiane Falge, Lothar Kanz, Andreas Neubauer, Michael Kneba, Frank Stegelmann, Michael Pfreundschuh, Cornelius F. Waller, Karsten Spiekermann, Gabriela M. Baerlocher, Markus Pfirrmann, Joerg Hasford, Wolf-Karsten Hofmann, Andreas Hochhaus, Martin C. Müller

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The BCR-ABLT315I mutation compromises survival in chronic phase chronic myelogenous leukemia patients resistant to tyrosine kinase inhibitors, in a matched pair analysis by Franck E. Nicolini, Amr R. Ibrahim, Simona Soverini, Giovanni Martinelli, Martin C. Müller, Andreas Hochhaus, Inge H. Dufva, Dong-Wook Kim, Jorge Cortes, Michael J. Mauro, Charles Chuah, Hélène Labussière, Stéphane Morisset, Catherine Roche-Lestienne, Eric Lippert, Sandrine Hayette, Senaka Peter, Wei Zhou, Véronique Maguer-Satta, Mauricette Michallet, John Goldman, Jane F. Apperley, François-Xavier Mahon, David Marin, Gabriel Etienne

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