Doxycycline inhibits MMPs via modulation of plasminogen activators in focal cerebral ischemia by Dorothe Burggraf, Andreas Trinkl, Martin Dichgans, Gerhard F. Hamann

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Additive Effects of Genetic Interleukin‐6 Signaling Downregulation and Low‐Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2×2 Factorial Mendelian Randomizati... by Marios K. Georgakis, Rainer Malik, Stephen Burgess, Martin Dichgans

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Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis by Dipender Gill, Marios K. Georgakis, Verena Zuber, Ville Karhunen, Stephen Burgess, Rainer Malik, Martin Dichgans

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Circulating biomarkers of immunity and inflammation, risk of Alzheimer’s disease, and hippocampal volume: a Mendelian randomization study by Lana Fani, Marios K. Georgakis, M. Arfan Ikram, M. Kamran Ikram, Rainer Malik, Martin Dichgans

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ADC histograms from routine DWI for longitudinal studies in cerebral small vessel disease: a field study in CADASIL. by Bence Gunda, Raphael Porcher, Marco Duering, Jean-Pierre Guichard, Jerome Mawet, Eric Jouvent, Martin Dichgans, Hugues Chabriat

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Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing by Isabel Weisheit, Joseph A. Kroeger, Rainer Malik, Julien Klimmt, Dennis Crusius, Angelika Dannert, Martin Dichgans, Dominik Paquet

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Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals by Davina Biel, Matthias Brendel, Anna Rubinski, Katharina Buerger, Daniel Janowitz, Martin Dichgans, Nicolai Franzmeier, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

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Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups by Marios K. Georgakis, Rainer Malik, Tom G. Richardson, Joanna M. M. Howson, Christopher D. Anderson, Stephen Burgess, G. Kees Hovingh, Martin Dichgans, Dipender Gill

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Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease by Anna Rubinski, Nicolai Franzmeier, Anna Dewenter, Ying Luan, Ruben Smith, Olof Strandberg, Rik Ossenkoppele, Martin Dichgans, Oskar Hansson, Michael Ewers, the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

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IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses by Yaw Asare, Margarita Shnipova, Luka Živković, Christina Schlegl, Federica Tosato, Arailym Aronova, Markus Brandhofer, Laura Strohm, Nathalie Beaufort, Rainer Malik, Christian Weber, Jürgen Bernhagen, Martin Dichgans

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What Is the Best Mix of Population‐Wide and High‐Risk Targeted Strategies of Primary Stroke and Cardiovascular Disease Prevention? by Valery L. Feigin, Michael Brainin, Bo Norrving, Philip B. Gorelick, Martin Dichgans, Wenzhi Wang, Jeyaraj Durai Pandian, Sheila Cristina Ouriques Martins, Mayowa O. Owolabi, David A. Wood, Graeme J. Hankey

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Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex by Christina Koupourtidou, Veronika Schwarz, Hananeh Aliee, Simon Frerich, Judith Fischer-Sternjak, Riccardo Bocchi, Tatiana Simon-Ebert, Xianshu Bai, Swetlana Sirko, Frank Kirchhoff, Martin Dichgans, Magdalena Götz, Fabian J. Theis, Jovica Ninkovic

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Different Types of White Matter Hyperintensities in CADASIL by Edouard Duchesnay, Fouad Hadj Selem, François De Guio, Mathieu Dubois, Jean-François Mangin, Marco Duering, Stefan Ropele, Reinhold Schmidt, Martin Dichgans, Hugues Chabriat, Hugues Chabriat, Hugues Chabriat, Eric Jouvent, Eric Jouvent, Eric Jouvent

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Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration by Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah Moore, Timothy J. Hohman, Estrella Morenas-Rodriguez, Brigitte Nuscher, Leslie Shaw, John Q. Trojanowski, Martin Dichgans, Gernot Kleinberger, Christian Haass, Michael Ewers, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

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The left frontal cortex supports reserve in aging by enhancing functional network efficiency by Nicolai Franzmeier, Julia Hartmann, Alexander N. W. Taylor, Miguel Á. Araque-Caballero, Lee Simon-Vermot, Lana Kambeitz-Ilankovic, Katharina Bürger, Cihan Catak, Daniel Janowitz, Claudia Müller, Birgit Ertl-Wagner, Robert Stahl, Martin Dichgans, Marco Duering, Michael Ewers

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Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease by Marco Egle, Saima Hilal, Anil M Tuladhar, Lukas Pirpamer, Steven Bell, Edith Hofer, Marco Duering, James Wason, Robin G Morris, Martin Dichgans, Reinhold Schmidt, Daniel J Tozer, Thomas R. Barrick, Christopher Chen, Frank-Erik de Leeuw, Hugh S Markus

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Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden by Marco Duering, Marek J. Konieczny, Steffen Tiedt, Ebru Baykara, Anil Man Tuladhar, Esther van Leijsen, Philippe Lyrer, Stefan T. Engelter, Benno Gesierich, Melanie Achmüller, Christian Barro, Ruth Adam, Michael Ewers, Martin Dichgans, Jens Kuhle, Frank-Erik de Leeuw, Nils Peters

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High‐Sensitivity Cardiac Troponin T and Cognitive Function Over 12 Months After Stroke—Results of the DEMDAS Study by Regina von Rennenberg, Christian H. Nolte, Thomas G. Liman, Simon Hellwig, Christoph Riegler, Jan F. Scheitz, Marios K. Georgakis, Rong Fang, Felix J. Bode, Gabor C. Petzold, Peter Hermann, Inga Zerr, Michael Goertler, Kathleen Bernkopf, Silke Wunderlich, Martin Dichgans, Matthias Endres

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Earlier Alzheimer’s disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading by Lukas Frontzkowski, Michael Ewers, Matthias Brendel, Davina Biel, Rik Ossenkoppele, Paul Hager, Anna Steward, Anna Dewenter, Sebastian Römer, Anna Rubinski, Katharina Buerger, Daniel Janowitz, Alexa Pichet Binette, Ruben Smith, Olof Strandberg, Niklas Mattsson Carlgren, Martin Dichgans, Oskar Hansson, Nicolai Franzmeier

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Higher CSF sTREM2 and microglia activation are associated with slower rates of beta‐amyloid accumulation by Michael Ewers, Gloria Biechele, Marc Suárez‐Calvet, Christian Sacher, Tanja Blume, Estrella Morenas‐Rodriguez, Yuetiva Deming, Laura Piccio, Carlos Cruchaga, Gernot Kleinberger, Leslie Shaw, John Q Trojanowski, Jochen Herms, Martin Dichgans, the Alzheimer's Disease Neuroimaging Initiative (ADNI), Matthias Brendel, Christian Haass, Nicolai Franzmeier

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