Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination by Jon Amund Kyte, Anne Fåne, Martin Pule, Gustav Gaudernack

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An Optimized GD2-Targeting Retroviral Cassette for More Potent and Safer Cellular Therapy of Neuroblastoma and Other Cancers. by Simon Thomas, Karin Straathof, Nourredine Himoudi, John Anderson, Martin Pule

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Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2 by Julia Taylor, Anna Bulek, Isaac Gannon, Mathew Robson, Evangelia Kokalaki, Thomas Grothier, Callum McKenzie, Mohamed El-Kholy, Maria Stavrou, Charlotte Traynor-White, Wen Chean Lim, Panagiota Panagiotou, Saket Srivastava, Vania Baldan, James Sillibourne, Mathieu Ferrari, Martin Pule, Martin Pule, Simon Thomas

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Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells by Kevin Lenogue, Alexandre Walencik, Karine Laulagnier, Jean-Paul Molens, Houssem Benlalam, Brigitte Dreno, Pierre Coulie, Martin Pule, Laurence Chaperot, Joël Plumas

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Novel Fas-TNFR chimeras that prevent Fas ligand-mediated kill and signal synergistically to enhance CAR T cell efficacy by Callum McKenzie, Mohamed El-Kholy, Farhaan Parekh, Mathew Robson, Katarina Lamb, Christopher Allen, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

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Large-scale manufacturing of base-edited chimeric antigen receptor T cells by Rosie Woodruff, Farhaan Parekh, Katarina Lamb, Leila Mekkaoui, Christopher Allen, Katerina Smetanova, Jasmine Huang, Alex Williams, Gerardo Santiago Toledo, Koki Lilova, Claire Roddie, James Sillibourne, Martin Pule

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Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction by Alastair Hotblack, Evangelia K. Kokalaki, Morgan J. Palton, Gordon Weng-Kit Cheung, Iwan P. Williams, Somayya Manzoor, Thomas I. Grothier, Alice Piapi, Valeria Fiaccadori, Patrycja Wawrzyniecka, Harriet A. Roddy, Giulia Agliardi, Claire Roddie, Shimobi Onuoha, Simon Thomas, Shaun Cordoba, Martin Pule

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Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing by Leila Mekkaoui, Jose G. Tejerizo, Sara Abreu, Lydie Rubat, Aleksandra Nikoniuk, William Macmorland, Claire Horlock, Sofia Matsumoto, Sarah Williams, Koval Smith, Juliet Price, Saket Srivastava, Rehan Hussain, Mohammad Amin Banani, William Day, Elena Stevenson, Meghan Madigan, Jie Chen, Ravin Khinder, Shahed Miah, Simon Walker, Michael Ade-Onojobi, Sabine Domining, James Sillibourne, Marianna Sabatino, Vladimir Slepushkin, Farzin Farzaneh, Martin Pule

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Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy by Simon Thomas, Julia Taylor, Manuel Rodriguez-Justo, Mathieu Ferrari, Shimobi Onuoha, Sonja Zweegman, Rakesh Popat, Lydia Lee, Wen Chean Lim, Daria Galas-Filipowicz, Kent Fung, Dominic Patel, Zulaikha Akbar, Elena Alvarez Mediavilla, Patrycja Wawrzyniecka, Debarati Shome, Rogier M Reijmers, Trillian Gregg, Leigh Wood, William Day, Virginie Cerec, Shaun Cordoba, Nushmia Khokhar, Vijay Peddareddigari, Muhammad Al-Hajj, Jim Cavet, Kwee Youg, Martin Pule

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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies by Mathieu Ferrari, Matteo Righi, Vania Baldan, Patrycja Wawrzyniecka, Anna Bulek, Alexander Kinna, Biao Ma, Reyisa Bughda, Zulaikha Akbar, Saket Srivastava, Isaac Gannon, Mathew Robson, James Sillibourne, Ram Jha, Mohamed El-Kholy, Oliver Muhammad Amin, Evangelia Kokalaki, Mohammed Amin Banani, Rehan Hussain, William Day, Wen Chean Lim, Priyanka Ghongane, Jade R. Hopkins, Dennis Jungherz, Marco Herling, Martin Welin, Sachin Surade, Michael Dyson, John McCafferty, Derek Logan, Shaun Cordoba, Simon Thomas, Andrew Sewell, Paul Maciocia, Shimobi Onuoha, Martin Pule

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S262: SAFETY AND EFFICACY OF OBECABTAGENE AUTOLEUCEL (OBE-CEL), A FAST-OFF RATE CD19 CAR IN RELAPSED/REFRACTORY ADULT B-CELL ACUTE LYMPHOBLASTIC LEUKAEMIA:TOP LINE RESULTS OF THE P... by Claire Roddie, Karamjeet Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba Suñol, Manuel Nuno Direito de Morais Guerreiro, Mehrdad Abedi, Michael Bishop, Jean Yared, Armin Ghobadi, Deborah Yallop, Aaron Logan, Beitinjaneh Amer, Jeremy Pantin, Martha L Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen Odwyer, Sameem Abedin, Hassan Alkhateeb, Bijal Shah, Silvia Basilico, Deborah Cluxton, Joanna Dawes, Pierre Lao-Sirieix, Meera Raymond, Justin Shang, Yanqing Hu, Gianfranco Pittari, Kapil Saxena, Wolfram Brugger, Y Zhang, Martin Pule, Daniel Park, Daniel De Angelo, Elias Jabbour

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