Editorial: Emerging receptors as new targets in health and disease by Julie Dam, Julien Hanson, Julien Hanson, Martyna Szpakowska

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Systematic Assessment of Human CCR7 Signalling Using NanoBRET Biosensors Points towards the Importance of the Cellular Context by Nathan Vanalken, Katrijn Boon, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy

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Systematic assessment of chemokine ligand bias at the human chemokine receptor CXCR2 indicates G protein bias over β-arrestin recruitment and receptor internalization by Katrijn Boon, Nathan Vanalken, Martyna Szpakowska, Andy Chevigné, Dominique Schols, Tom Van Loy

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The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B by Giulia D’Uonnolo, Giulia D’Uonnolo, Nathan Reynders, Nathan Reynders, Max Meyrath, Dayana Abboud, Tomasz Uchański, Toon Laeremans, Brian F. Volkman, Bassam Janji, Julien Hanson, Julien Hanson, Martyna Szpakowska, Martyna Szpakowska, Andy Chevigné

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Patient-Oriented Perspective on Chemokine Receptor Expression and Function in Glioma by Damla Isci, Giulia D’Uonnolo, May Wantz, Bernard Rogister, Arnaud Lombard, Andy Chevigné, Martyna Szpakowska, Virginie Neirinckx

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The natural analgesic conolidine targets the newly identified opioid scavenger ACKR3/CXCR7 by Martyna Szpakowska, Ann M. Decker, Max Meyrath, Christie B. Palmer, Bruce E. Blough, Ojas A. Namjoshi, Andy Chevigné

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The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment by Nathan Reynders, Dayana Abboud, Alessandra Baragli, Muhammad Zaeem Noman, Bernard Rogister, Simone P. Niclou, Nikolaus Heveker, Bassam Janji, Julien Hanson, Martyna Szpakowska, Andy Chevigné

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CXCL14 Preferentially Synergizes With Homeostatic Chemokine Receptor Systems by Ariadni Kouzeli, Paul J. Collins, Mieke Metzemaekers, Max Meyrath, Martyna Szpakowska, Marc Artinger, Sofie Struyf, Paul Proost, Andy Chevigne, Daniel F. Legler, Matthias Eberl, Bernhard Moser

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New pairings and deorphanization among the atypical chemokine receptor family — physiological and clinical relevance by Martyna Szpakowska, Giulia D’Uonnolo, Giulia D’Uonnolo, Rafael Luís, Rafael Luís, Rafael Luís, Ana Alonso Bartolomé, Ana Alonso Bartolomé, Marcus Thelen, Daniel F. Legler, Andy Chevigné

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CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6 by Andy Chevigné, Bassam Janji, Max Meyrath, Nathan Reynders, Giulia D’Uonnolo, Tomasz Uchański, Malina Xiao, Guy Berchem, Markus Ollert, Yong-Jun Kwon, Muhammad Zaeem Noman, Martyna Szpakowska

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Reply to: How carvedilol does not activate β2-adrenoceptors by Evi Kostenis, Jesus Gomeza, Elke Miess-Tanneberg, Nina Kathleen Blum, Tobias Benkel, Andy Chevigné, Carsten Hoffmann, Peter Kolb, Viacheslav Nikolaev, Maria Waldhoer, Martyna Szpakowska, Asuka Inoue, Stefan Schulz

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The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides by Max Meyrath, Martyna Szpakowska, Julian Zeiner, Laurent Massotte, Myriam P. Merz, Tobias Benkel, Katharina Simon, Jochen Ohnmacht, Jonathan D. Turner, Rejko Krüger, Vincent Seutin, Markus Ollert, Evi Kostenis, Andy Chevigné

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Computationally designed GPCR quaternary structures bias signaling pathway activation by Justine S. Paradis, Xiang Feng, Brigitte Murat, Robert E. Jefferson, Badr Sokrat, Martyna Szpakowska, Mireille Hogue, Nick D. Bergkamp, Franziska M. Heydenreich, Martine J. Smit, Andy Chevigné, Michel Bouvier, Patrick Barth

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GPR182 is a broadly scavenging atypical chemokine receptor influencing T-independent immunity by Serena Melgrati, Serena Melgrati, Oliver J. Gerken, Oliver J. Gerken, Marc Artinger, Marc Artinger, Egle Radice, Martyna Szpakowska, Andy Chevigné, Giulia D’Uonnolo, Paola Antonello, Sylvia Thelen, Pawel Pelczar, Daniel F. Legler, Daniel F. Legler, Daniel F. Legler, Marcus Thelen

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Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome by Rajesh Kumar, Samantha Milanesi, Martyna Szpakowska, Laura Dotta, Dario Di Silvestre, Anna Maria Trotta, Anna Maria Bello, Mauro Giacomelli, Manuela Benedito, Joana Azevedo, Alexandra Pereira, Emilia Cortesao, Alessandro Vacchini, Alessandra Castagna, Marinella Pinelli, Daniele Moratto, Raffaella Bonecchi, Massimo Locati, Stefania Scala, Andy Chevigné, Elena M. Borroni, Raffaele Badolato

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Formate promotes invasion and metastasis in reliance on lipid metabolism by Catherine Delbrouck, Nicole Kiweler, Oleg Chen, Vitaly I. Pozdeev, Lara Haase, Laura Neises, Anaïs Oudin, Aymeric Fouquier d’Hérouël, Ruolin Shen, Lisa Schlicker, Rashi Halder, Antoine Lesur, Anne Schuster, Nadja I. Lorenz, Christian Jaeger, Maureen Feucherolles, Gilles Frache, Martyna Szpakowska, Andy Chevigne, Michael W. Ronellenfitsch, Etienne Moussay, Marie Piraud, Alexander Skupin, Almut Schulze, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

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Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model by Adam M. Passman, Robyn P. Strauss, Sarah B. McSpadden, Megan Finch-Edmondson, Neil Andrewartha, Ken H. Woo, Luke A. Diepeveen, Weihao Zhao, Joaquín Fernández-Irigoyen, Enrique Santamaría, Laura Medina-Ruiz, Martyna Szpakowska, Andy Chevigné, Hyerin Park, Rodrigo Carlessi, Janina E. E. Tirnitz-Parker, José R. Blanco, Roslyn London, Bernard A. Callus, Caryn L. Elsegood, Murray V. Baker, Alfredo Martínez, George C. T. Yeoh, Laura Ochoa-Callejero

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How Carvedilol activates β2-adrenoceptors by Tobias Benkel, Mirjam Zimmermann, Julian Zeiner, Sergi Bravo, Nicole Merten, Victor Jun Yu Lim, Edda Sofie Fabienne Matthees, Julia Drube, Elke Miess-Tanneberg, Daniela Malan, Martyna Szpakowska, Stefania Monteleone, Jak Grimes, Zsombor Koszegi, Yann Lanoiselée, Shannon O’Brien, Nikoleta Pavlaki, Nadine Dobberstein, Asuka Inoue, Viacheslav Nikolaev, Davide Calebiro, Andy Chevigné, Philipp Sasse, Stefan Schulz, Carsten Hoffmann, Peter Kolb, Maria Waldhoer, Katharina Simon, Jesus Gomeza, Evi Kostenis

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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors by Anna L. Gray, Richard Karlsson, Abigail R.E. Roberts, Amanda J.L. Ridley, Nabina Pun, Bakhtbilland Khan, Craig Lawless, Rafael Luís, Martyna Szpakowska, Andy Chevigné, Catherine E. Hughes, Laura Medina-Ruiz, Holly L. Birchenough, Iashia Z. Mulholland, Catherina L. Salanga, Edwin A. Yates, Jeremy E. Turnbull, Tracy M. Handel, Gerard J. Graham, Thomas A. Jowitt, Ingo Schiessl, Ralf P. Richter, Rebecca L. Miller, Douglas P. Dyer

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S141: INHIBITION OF MYC TRANSLATION THROUGH TARGETING OF THE NEWLY IDENTIFIED PHB-EIF4F COMPLEX AS THERAPEUTIC STRATEGY INCHRONIC LYMPHOCYTIC LEUKEMIA (CLL) by Anne Largeot, Vanessa Klapp, Elodie Viry, Susanne Gonder, Iria Fernandez Botana, Arnaud Blomme, Mohaned Benzarti, Sandrine Pierson, Chloé Duculty, Petra Marttila, Marina Wierz, Ernesto Gargiulo, Giulia Pagano, Ning An, Najla El Hachem, Daniel Perez Hernandez, Supriya Chakraborty, Loic Ysebaert, Jean-Hugues François, Susan Cortez, Guy Berchem, Dimitar G Efremov, Gunnar Dittmar, Martyna Szpakowska, Andy Chevigne, Petr V. Nazarov, Thomas Helleday, Pierre Close, Johannes Meiser, Basile Stamatopoulos, Laurent Désaubry, Jérôme Paggetti, Etienne Moussay

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