Immunohistochemistry and oxygen saturation endoscopic imaging reveal hypoxia in submucosal invasive esophageal squamous cell carcinoma by Nobuhisa Minakata, Shingo Sakashita, Masashi Wakabayashi, Yuka Nakamura, Hironori Sunakawa, Yusuke Yoda, Genichiro Ishii, Tomonori Yano

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Comparison between three age-stratified cohorts reveals poor prognosis of young patients with tongue carcinoma by Daisuke Baba, Kazuto Matsuura, Masashi Wakabayashi, Yohei Morishita, Yukio Nishiya, Wataru Okano, Toshifumi Tomioka, Takeshi Shinozaki, Ryuichi Hayashi

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A phase III study of adjuvant chemotherapy in patients with completely resected, node-negative non–small cell lung cancer (JCOG 0707)Central MessagePerspective by Hideo Kunitoh, MD, Masahiro Tsuboi, MD, Masashi Wakabayashi, MSc, Morihito Okada, MD, Kenji Suzuki, MD, Shun-ichi Watanabe, MD, Hisao Asamura, MD, H. Fukuda, T. Shibata, T. Kazato, T. Mizutani, J. Eba

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NEXUS trial: a multicenter phase II clinical study evaluating the efficacy and safety of the perioperative use of encorafenib, binimetinib, and cetuximab in patients with previousl... by Shin Kobayashi, Hideaki Bando, Akinobu Taketomi, Takeshi Takamoto, Eiji Shinozaki, Manabu Shiozawa, Hiroki Hara, Kentaro Yamazaki, Koji Komori, Nobuhisa Matsuhashi, Takeshi Kato, Yoshinori Kagawa, Mitsuru Yokota, Eiji Oki, Keigo Komine, Shinichiro Takahashi, Masashi Wakabayashi, Takayuki Yoshino

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TENERGY: multicenter phase II study of Atezolizumab monotherapy following definitive Chemoradiotherapy with 5-FU plus Cisplatin in patients with unresectable locally advanced esoph... by Hideaki Bando, Daisuke Kotani, Takahiro Tsushima, Hiroki Hara, Shigenori Kadowaki, Ken Kato, Keisho Chin, Kensei Yamaguchi, Shun-ichiro Kageyama, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana, Masashi Wakabayashi, Miki Fukutani, Yosuke Togashi, Nozomu Fuse, Hiroyoshi Nishikawa, Takashi Kojima

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Rationale and design of the BRAVERY study (EPOC1701): a multicentre phase II study of eribulin in patients with BRAF V600E mutant metastatic colorectal cancer by Hideaki Bando, Atsushi Ohtsu, Takayuki Yoshino, Toshiki Masuishi, Hiroya Taniguchi, Daisuke Kotani, Yoshito Komatsu, Eiji Shinozaki, Takako Eguchi Nakajima, Taroh Satoh, Tomohiro Nishina, Taito Esaki, Masashi Wakabayashi, Shogo Nomura, Koji Takahashi, Hiromi Ono, Nami Hirano, Noriko Fujishiro, Nozomu Fuse, Akihiro Sato

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First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors by Kohei Shitara, Satoshi Ueha, Shigeyuki Shichino, Hiroyasu Aoki, Haru Ogiwara, Tetsuya Nakatsura, Toshihiro Suzuki, Manami Shimomura, Toshiaki Yoshikawa, Kayoko Shoda, Shigehisa Kitano, Makiko Yamashita, Takayuki Nakayama, Akihiro Sato, Sakiko Kuroda, Masashi Wakabayashi, Shogo Nomura, Shoji Yokochi, Satoru Ito, Kouji Matsushima, Toshihiko Doi

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Identification of patient subgroups with unfavorable long‐term outcomes associated with laparoscopic surgery in a randomized controlled trial comparing open and laparoscopic surger... by Shuji Saito, Tomonori Akagi, Hiroshi Katayama, Masashi Wakabayashi, Masafumi Inomata, Seiichiro Yamamoto, Masaaki Ito, Yusuke Kinugasa, Hiroyuki Egi, Yasuhiro Munakata, Yukihito Kokuba, Hiroyuki Bando, Masayoshi Yasui, Masataka Ikeda, Kentaro Nakajima, Dai Shida, Yukihide Kanemitsu, Seigo Kitano, the Colorectal Cancer Study Group of Japan Clinical Oncology Group

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Mitigation of paclitaxel-induced peripheral neuropathy in breast cancer patients using limb-cooling apparatus: a study protocol for a randomized controlled trial by Chikako Funasaka, Chikako Funasaka, Akiko Hanai, Sadamoto Zenda, Sadamoto Zenda, Keita Mori, Makoto Fukui, Nami Hirano, Rie Shinohara, Nozomu Fuse, Masashi Wakabayashi, Mai Itagaki, Yutaka Tomioka, Michihiko Nishina, Yasuaki Arai, Takahiro Kogawa, Yukinori Ozaki, Yukinori Ozaki, Meiko Nishimura, Takayuki Kobayashi, Fumikata Hara, Toshimi Takano, Toru Mukohara

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Multiomic molecular characterization of the response to combination immunotherapy in MSS/pMMR metastatic colorectal cancer by Naoya Sakamoto, Saori Mishima, Akihito Kawazoe, Yasutoshi Kuboki, Hideaki Bando, Takashi Kojima, Takayuki Yoshino, Takeshi Kuwata, Kohei Shitara, Yoshiaki Nakamura, Daisuke Kotani, Masashi Wakabayashi, Shohei Koyama, Hiroyoshi Nishikawa, Yosuke Tanaka, Shogo Takei, Itaru Endo, Motohiro Kojima, Toshihide Ueno, Hiroyuki Mano, Shota Fukuoka, Yi-Tzu Lin, Hiroki Hara, Shinya Kojima

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Prospective, Multi-Institutional Observational Study of Deterioration in Activities of Daily Living in Elderly Patients After Lung Cancer Surgery by Hidefumi Takei, MD, Hideo Kunitoh, MD, Masashi Wakabayashi, MSc, Tomoko Kataoka, DDS, Yuta Sekino, MD, Tomonori Mizutani, MD, Masahiro Tsuboi, MD, Norihiko Ikeda, MD, Hisao Asamura, MD, Morihito Okada, MD, Makoto Takahama, MD, Yasuhisa Ohde, MD, Jiro Okami, MD, Satoshi Shiono, MD, Keijyu Aokage, MD, Shun-ichi Watanabe, MD, H. Fukuda, T. Shibata

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