P16-28. The first year: early correlates of long-term HIV progression by Michael NL, Ganesan A, Mascola JR, Brodie T, Chattopadhyay PK, Roederer M

Priming with DNA encoding functional trimers and boosting with soluble trimeric protein elicited tier 2 neutralizing antibodies in non-human primates by Chakrabarti BK, Yu F, McKee K, Labranche C, Montefiori D, Mascola JR, Wyatt RT

Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120 by Zhou T, Moquin S, Lynch R, Wu X, Zhu J, Yang Y, Zhang B, Mascola JR, Kwong PD

Isolation of broadly neutralizing HIV-1 antibodies from high-throughput single B cell culture by Longo NS, Doria-Rose N, McKee K, O'Dell S, Louder MK, Yang Z, Bailer R, Mascola JR

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site by Dai K, Boyington JC, Shi W, Schmidt SD, Georgiev I, Lingwood D, Kwong PD, Mascola JR, Yang Z, Nabel GJ

Partial germline reversions can increase VRC07 potency and breadth by Rudicell RS, Georgiev I, Yang Z, O'Dell S, Kwon Y, Zhu J, Wu X, Kwong PD, Mascola JR, Nabel GJ

HIV-Specific Antibodies Mediate Rapid Antibody-Dependent Cellular Cytotoxicity Against Primary HIV-Infected CD4+T Cells by Smalls-Mantey, A, Klein, R, Doria-Rose, N, Laub, L, Rood, J, Migueles, SA, Mascola, JR, Sattentau, Q, Connors, M

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization by Acharya P, Luongo TS, Matz J, Schmidt SD, Chuang G, Georgiev I, Kessler P, Yang Y, Chames P, Martin L, Mascola JR, Kwong PD

P14-10. Comparable immunogenicity of VRC DNA and rAd5 HIV-1 vaccines delivered by intramuscular, subcutaneous and intradermal routes in healthy adults (VRC 011) by Nabel GJ, Mascola JR, Koup RA, Roederer M, Bailer RT, Nason MC, Holman LA, Gordon IJ, Enama ME, Novik L, Ledgerwood JE, Graham BS

Design of epitope-specific probes for sera analysis and antibody isolation by Georgiev I, Acharya P, Schmidt SD, Li Y, Wycuff D, Ofek G, Doria-Rose N, Luongo TS, Yang Y, Zhou T, Donald BR, Mascola JR, Kwong PD

Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. by Duvall, MG, Loré, K, Blaak, H, Ambrozak, D, Adams, W, Santos, K, Geldmacher, C, Mascola, JR, Mcmichael, A, Jaye, A, Whittle, H, Rowland-Jones, S, Koup, R

A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies by Doria-Rose NA, Georgiev I, Staupe RP, O'Dell S, Chuang G, Gorman J, McLellan JS, Pancera M, Bonsignori M, Haynes BF, Burton DR, Koff WC, Kwong PD, Mascola JR

HIV-1 envelope glycan modifications that permit neutralization by germline-reverted VRC01-class broadly neutralizing antibodies by Labranche, CC, McGuire, AT, Gray, MD, Behrens, S, Zhou, T, Sattentau, QJ, Peacock, J, Eaton, A, Greene, K, Gao, H, Tang, H, Perez, LG, Saunders, KO, Mascola, JR, Haynes, BF, Stamatatos, L, Montefiori, DC

Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant by Francica, JR, Lynn, GM, Laga, R, Joyce, MG, Ruckwardt, TJ, Morabito, KM, Chen, M, Chaudhuri, R, Zhang, B, Sastry, M, Druz, A, Ko, K, Choe, M, Pechar, M, Georgiev, IS, Kueltzo, LA, Seymour, LW, Mascola, JR, Kwong, PD, Graham, BS, Seder, RA

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies by LaBranche, C, Henderson, R, Hsu, A, Behrens, S, Chen, X, Zhou, T, Wiehe, K, Saunders, KO, Alam, SM, Bonsignori, M, Borgnia, MJ, Sattentau, QJ, Eaton, A, Greene, K, Gao, H, Liao, HX, Williams, WB, Peacock, J, Tang, H, Perez, LG, Edwards, RJ, Kepler, TB, Korber, BT, Kwong, PD, Mascola, JR, Acharya, P, Haynes, BF, Montefiori, DC

Design of an HIV Env antigen that binds with high affinity to antibodies against linear, conformational and broadly neutralizing epitopes within V1/V2 by Liao L, Bonsignori M, Hwang K, Moody AM, Park R, Crawford S, Chen H, Jeffries TL, Cooper M, Lu X, De R, Karasavvas N, Rerks-Ngarm S, Nitayaphan S, Kaewkungwal J, Tovanabutra S, Pitisuttithum P, Tartaglia J, Sinangil F, Kim J, Michael NL, Tomaras GD, Yang Z, Dai K, Pancera M, Nabel GJ, Mascola JR, Kwong PD, Pinter A, Zolla-Pazner S, Alam MS, Haynes BF