Heritability of the glycan clock of biological age av Anika Mijakovac, Azra Frkatović, Maja Hanić, Jelena Ivok, Marina Martinić Kavur, Maja Pučić-Baković, Tim Spector, Vlatka Zoldoš, Massimo Mangino, Massimo Mangino, Gordan Lauc, Gordan Lauc

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Innate and adaptive immune traits are differentially affected by genetic and environmental factors av Massimo Mangino, Mario Roederer, Margaret H. Beddall, Frank O. Nestle, Tim D. Spector

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Immune Trait Shifts in Association With Tobacco Smoking: A Study in Healthy Women av Giulia Piaggeschi, Giulia Piaggeschi, Simona Rolla, Niccolò Rossi, Davide Brusa, Alessio Naccarati, Alessio Naccarati, Simon Couvreur, Tim D. Spector, Mario Roederer, Massimo Mangino, Massimo Mangino, Francesca Cordero, Mario Falchi, Alessia Visconti

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Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches av Gordan Lauc, Markus Perola, Domagoj Kifer, Olga Gornik, Massimo Mangino, Ana Cvetko, Marko Tijardović, Toma Keser

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The rate of nonallelic homologous recombination in males is highly variable, correlated between monozygotic twins and independent of age. av Jacqueline A L MacArthur, Timothy D Spector, Sarah J Lindsay, Massimo Mangino, Raj Gill, Kerrin S Small, Matthew E Hurles

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Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples av Thomas Liechti, Yaser Iftikhar, Massimo Mangino, Margaret Beddall, Charles W. Goss, Jane A. O’Halloran, Philip A. Mudd, Mario Roederer

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Omega-6 oxylipins generated by soluble epoxide hydrolase are associated with knee osteoarthritis av Ana M. Valdes, Srinivasarao Ravipati, Petros Pousinis, Cristina Menni, Massimo Mangino, Abhishek Abhishek, Victoria Chapman, David A. Barrett, Michael Doherty

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Characterizing Blood Metabolomics Profiles Associated with Self-Reported Food Intakes in Female Twins. av Tess Pallister, Amy Jennings, Robert P Mohney, Darioush Yarand, Massimo Mangino, Aedin Cassidy, Alexander MacGregor, Tim D Spector, Cristina Menni

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Machine learning integration of multimodal data identifies key features of blood pressure regulation av Panayiotis Louca, Tran Quoc Bao Tran, Clea du Toit, Paraskevi Christofidou, Tim D. Spector, Massimo Mangino, Karsten Suhre, Sandosh Padmanabhan, Cristina Menni

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Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms. av Idil Yet, Cristina Menni, So-Youn Shin, Massimo Mangino, Nicole Soranzo, Jerzy Adamski, Karsten Suhre, Tim D Spector, Gabi Kastenmüller, Jordana T Bell

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Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis. av Nicholas S Kalson, Tim M Brock, Massimo Mangino, Stella M Fabiane, Derek A Mann, Lee A Borthwick, David J Deehan, Frances M K Williams

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Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels av Pirro G. Hysi, Massimo Mangino, Paraskevi Christofidou, Mario Falchi, Edward D. Karoly, NIHR Bioresource Investigators, Robert P. Mohney, Ana M. Valdes, Tim D. Spector, Cristina Menni

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Obligatory and facilitative allelic variation in the DNA methylome within common disease-associated loci av Christopher G. Bell, Fei Gao, Wei Yuan, Leonie Roos, Richard J. Acton, Yudong Xia, Jordana Bell, Kirsten Ward, Massimo Mangino, Pirro G. Hysi, Jun Wang, Timothy D. Spector

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A robust pipeline for high-content, high-throughput immunophenotyping reveals age- and genetics-dependent changes in blood leukocytes av Thomas Liechti, Sofie Van Gassen, Margaret Beddall, Reid Ballard, Yaser Iftikhar, Renguang Du, Thiagarajan Venkataraman, David Novak, Massimo Mangino, Stephen Perfetto, H. Benjamin Larman, Tim Spector, Yvan Saeys, Mario Roederer

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A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients av Ricardo Khouri, Gilvanéia Silva-Santos, Tim Dierckx, Soraya Maria Menezes, Daniele Decanine, Kristof Theys, Aline Clara Silva, Lourdes Farré, Achiléa Bittencourt, Massimo Mangino, Mario Roederer, Anne-Mieke Vandamme, Johan Van Weyenbergh

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Glycosylation of immunoglobulin g: role of genetic and epigenetic influences. av Cristina Menni, Toma Keser, Massimo Mangino, Jordana T Bell, Idil Erte, Irena Akmačić, Frano Vučković, Maja Pučić Baković, Olga Gornik, Mark I McCarthy, Vlatka Zoldoš, Tim D Spector, Gordan Lauc, Ana M Valdes

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High intake of vegetables is linked to lower white blood cell profile and the effect is mediated by the gut microbiome av Cristina Menni, Panayiotis Louca, Sarah E. Berry, Amrita Vijay, Stuart Astbury, Emily R. Leeming, Rachel Gibson, Francesco Asnicar, Gianmarco Piccinno, Jonathan Wolf, Richard Davies, Massimo Mangino, Nicola Segata, Tim D. Spector, Ana M. Valdes

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Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation av Xia Shen, Lucija Klarić, Sodbo Sharapov, Massimo Mangino, Zheng Ning, Di Wu, Irena Trbojević-Akmačić, Maja Pučić-Baković, Igor Rudan, Ozren Polašek, Caroline Hayward, Timothy D. Spector, James F. Wilson, Gordan Lauc, Yurii S. Aulchenko

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Plasma protein N-glycome composition associates with postprandial lipaemic response av Panayiotis Louca, Tamara Štambuk, Azra Frkatović-Hodžić, Ana Nogal, Massimo Mangino, Sarah E. Berry, Helena Deriš, George Hadjigeorgiou, Jonathan Wolf, Martina Vinicki, Paul W. Franks, Ana M. Valdes, Tim D. Spector, Gordan Lauc, Cristina Menni

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Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes av Cristina Menni, Jialing Zhu, Caroline I Le Roy, Olatz Mompeo, Kristin Young, Casey M. Rebholz, Elizabeth Selvin, Kari E. North, Robert P Mohney, Jordana T Bell, Eric Boerwinkle, Tim D Spector, Massimo Mangino, Bing Yu, Ana M Valdes

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