The gating mechanism of the human aquaporin 5 revealed by molecular dynamics simulations. by Lorant Janosi, Matteo Ceccarelli

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Exploring binding properties of agonists interacting with a δ-opioid receptor. by Francesca Collu, Matteo Ceccarelli, Paolo Ruggerone

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The Influence of Permeability through Bacterial Porins in Whole-Cell Compound Accumulation by Silvia Acosta-Gutiérrez, Igor V. Bodrenko, Matteo Ceccarelli

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Ab Initio Spectroscopic Investigation of Pharmacologically Relevant Chiral Molecules: The Cases of Avibactam, Cephems, and Idelalisib as Benchmarks for Antibiotics and Anticancer D... by Elena Molteni, Giovanni Onida, Matteo Ceccarelli, Giancarlo Cappellini

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The Optimal Permeation of Cyclic Boronates to Cross the Outer Membrane via the Porin Pathway by Gian Marco Tuveri, Matteo Ceccarelli, Alessandro Pira, Igor V. Bodrenko

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A Database of Force-Field Parameters, Dynamics, and Properties of Antimicrobial Compounds by Giuliano Malloci, Attilio Vittorio Vargiu, Giovanni Serra, Andrea Bosin, Paolo Ruggerone, Matteo Ceccarelli

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The Discovery of Naringenin as Endolysosomal Two-Pore Channel Inhibitor and Its Emerging Role in SARS-CoV-2 Infection by Antonella D’Amore, Antonella Gradogna, Fioretta Palombi, Velia Minicozzi, Matteo Ceccarelli, Armando Carpaneto, Antonio Filippini

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Permeation of β-Lactamase Inhibitors through the General Porins of Gram-Negative Bacteria by Alessandro Pira, Mariano Andrea Scorciapino, Igor V. Bodrenko, Andrea Bosin, Silvia Acosta-Gutiérrez, Matteo Ceccarelli

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Folded Structure and Membrane Affinity of the N‑Terminal Domain of the Three Human Isoforms of the Mitochondrial Voltage-Dependent Anion-Selective Channel by Giorgia Manzo, Ilaria Serra, Andrea Magrí, Mariano Casu, Vito De Pinto, Matteo Ceccarelli, Mariano Andrea Scorciapino

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Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii by Lucile Moynié, Ilaria Serra, Mariano A Scorciapino, Emilia Oueis, Malcolm GP Page, Matteo Ceccarelli, James H Naismith

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Randomized Phase 2 Clinical Trial of Olaratumab in Combination with Gemcitabine and Docetaxel in Advanced Soft Tissue Sarcomas by Steven Attia, Victor Villalobos, Nadia Hindi, Andrew J. Wagner, Bartosz Chmielowski, Gerard J. Oakley, Patrick M. Peterson, Matteo Ceccarelli, Robin L. Jones, Mark A. Dickson

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Electrophysiological properties and structural prediction of the SARS-CoV-2 viroprotein E by Salvatore Antonio Maria Cubisino, Stefan Milenkovic, Stefano Conti-Nibali, Nicolò Musso, Paolo Bonacci, Vito De Pinto, Vito De Pinto, Matteo Ceccarelli, Simona Reina, Simona Reina

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Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli. by Hubing Lou, Min Chen, Susan S Black, Simon R Bushell, Matteo Ceccarelli, Tivadar Mach, Konstantinos Beis, Alison S Low, Victoria A Bamford, Ian R Booth, Hagan Bayley, James H Naismith

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Results of a Randomized, Double-Blind, Placebo-Controlled, Phase 1b/2 Trial of Nabpaclitaxel + Gemcitabine ± Olaratumab in Treatment-Naïve Participants with Metastatic Pancreatic C... by Faithlore P. Gardner, Zev A. Wainberg, Christos Fountzilas, Nathan Bahary, Mark S. Womack, Teresa Macarulla, Ignacio Garrido-Laguna, Patrick M. Peterson, Erkut Borazanci, Melissa Johnson, Matteo Ceccarelli, Uwe Pelzer

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The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model by Lucile Moynié, Stefan Milenkovic, Gaëtan L. A. Mislin, Véronique Gasser, Giuliano Malloci, Etienne Baco, Rory P. McCaughan, Malcolm G. P. Page, Isabelle J. Schalk, Matteo Ceccarelli, James H. Naismith

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Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo by Magdalena Bachmann, Andrea Rossa, Tatiana Varanita, Bernard Fioretti, Lucia Biasutto, Stefan Milenkovic, Vanessa Checchetto, Roberta Peruzzo, Syed A. Ahmad, Sameer H. Patel, Robert Lukowski, Michael J. Edwards, Matteo Ceccarelli, Erich Gulbins, Mario Zoratti, Andrea Mattarei, Ildiko Szabo

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Current Methods to Unravel the Functional Properties of Lysosomal Ion Channels and Transporters by Margherita Festa, Velia Minicozzi, Anna Boccaccio, Laura Lagostena, Antonella Gradogna, Tianwen Qi, Alex Costa, Nina Larisch, Shin Hamamoto, Emanuela Pedrazzini, Stefan Milenkovic, Joachim Scholz-Starke, Matteo Ceccarelli, Alessandro Vitale, Petra Dietrich, Nobuyuki Uozumi, Franco Gambale, Armando Carpaneto

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RELAY+: Exploratory Study of Ramucirumab Plus Gefitinib in Untreated Patients With EGFR-Mutated Metastatic NSCLC by Makoto Nishio, MD, PhD, Kazuto Nishio, MD, PhD, Martin Reck, MD, PhD, Edward B. Garon, MD, Fumio Imamura, MD, PhD, Tomoya Kawaguchi, PhD, Hiroyuki Yamaguchi, MD, PhD, Satoshi Ikeda, MD, PhD, Katsuya Hirano, MD, Carla Visseren-Grul, MD, Matteo Ceccarelli, PharmD, MS, Sameera R. Wijayawardana, PhD, Annamaria Zimmermann, MS, Tomoko Matsui, Sotaro Enatsu, MD, PhD, Kazuhiko Nakagawa, MD, PhD

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