The past, present and future of anti-malarial medicines by Edwin G. Tse, Marat Korsik, Matthew H. Todd

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Open science approaches to COVID-19 [version 1; peer review: 2 approved] by Edwin G. Tse, Dana M. Klug, Matthew H. Todd

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Can we measure catalyst efficiency in asymmetric chemical reactions? A theoretical approach by Shaimaa El-Fayyoumy, Matthew H. Todd, Christopher J. Richards

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Recent Advances in Macrocyclic Fluorescent Probes for Ion Sensing by Joseph K.-H. Wong, Matthew H. Todd, Peter J. Rutledge

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The outcome of the oxidations of unusual enediamide motifs is governed by the stabilities of the intermediate iminium ions. by Muneer Ahamed, Muneer Ahamed, Bun Chan, Paul Jensen, Matthew H Todd

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A direct method for the N-tetraalkylation of azamacrocycles by Andrew J. Counsell, Angus T. Jones, Matthew H. Todd, Peter J. Rutledge

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Efficient Synthesis and Anti-Tubercular Activity of a Series of Spirocycles: An Exercise in Open Science. by Katrina A Badiola, Diana H Quan, James A Triccas, Matthew H Todd

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Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal. by Anthony T S Lo, Noeris K Salam, David E Hibbs, Peter J Rutledge, Matthew H Todd

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Resolution of praziquantel. by Michael Woelfle, Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer, Piero Olliaro, Matthew H Todd

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Incorporating a piperidinyl group in the fluorophore extends the fluorescence lifetime of click-derived cyclam-naphthalimide conjugates. by Mingfeng Yu, Sandra Ast, Qun Yu, Anthony T S Lo, Roman Flehr, Matthew H Todd, Peter J Rutledge

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Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids by Mingfeng Yu, Joseph K.-H. Wong, Cyril Tang, Peter Turner, Matthew H. Todd, Peter J. Rutledge

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Identification of Dihydropyrazolo[1,5-<i>a</i>]pyrazin-4(5<i>H</i>)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors by Anirban Ghoshal, Álvaro F. Magalhães, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Matthew H. Todd, Timothy M. Willson

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Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities by Saba Munawar, Saba Munawar, Monique J. Windley, Edwin G. Tse, Matthew H. Todd, Adam P. Hill, Jamie I. Vandenberg, Ishrat Jabeen

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An open source pharma roadmap. by Manica Balasegaram, Peter Kolb, John McKew, Jaykumar Menon, Piero Olliaro, Tomasz Sablinski, Zakir Thomas, Matthew H Todd, Els Torreele, John Wilbanks

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Ten simple rules for cultivating open science and collaborative R&D. by Hassan Masum, Aarthi Rao, Benjamin M Good, Matthew H Todd, Aled M Edwards, Leslie Chan, Barry A Bunin, Andrew I Su, Zakir Thomas, Philip E Bourne

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Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma. by Wilson Lim, Youri Melse, Mickey Konings, Hung Phat Duong, Kimberly Eadie, Benoît Laleu, Benjamin Perry, Matthew H Todd, Jean-Robert Ioset, Wendy W J van de Sande

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There is no market for new antibiotics: this allows an open approach to research and development [version 1; peer review: 2 approved] by Dana M. Klug, Fahima I. M. Idiris, Mark A. T. Blaskovich, Frank von Delft, Christopher G. Dowson, Claas Kirchhelle, Adam P. Roberts, Andrew C. Singer, Matthew H. Todd

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A kernel for open source drug discovery in tropical diseases. by Leticia Ortí, Rodrigo J Carbajo, Ursula Pieper, Narayanan Eswar, Stephen M Maurer, Arti K Rai, Ginger Taylor, Matthew H Todd, Antonio Pineda-Lucena, Andrej Sali, Marc A Marti-Renom

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase by Stanley C. Xie, Yinuo Wang, Craig J. Morton, Riley D. Metcalfe, Con Dogovski, Charisse Flerida A. Pasaje, Elyse Dunn, Madeline R. Luth, Krittikorn Kumpornsin, Eva S. Istvan, Joon Sung Park, Kate J. Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N. Bhebhe, Dana M. Klug, Peter J. Rutledge, Luiz C. Godoy, Sumanta Dey, Mariana Laureano De Souza, Jair L. Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerry Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas Williamson, Gouranga P. Jana, Bikash C. Maity, Patrick Thomson, Thomas Foley, Derek S. Tan, Jacquin C. Niles, Byung Woo Han, Daniel E. Goldberg, Jeremy Burrows, David A. Fidock, Marcus C. S. Lee, Elizabeth A. Winzeler, Michael D. W. Griffin, Matthew H. Todd, Leann Tilley

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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles by Alice E. Williamson, Paul M. Ylioja, Murray N. Robertson, Yevgeniya Antonova-Koch, Vicky Avery, Jonathan B. Baell, Harikrishna Batchu, Sanjay Batra, Jeremy N. Burrows, Soumya Bhattacharyya, Felix Calderon, Susan A. Charman, Julie Clark, Benigno Crespo, Matin Dean, Stefan L. Debbert, Michael Delves, Adelaide S. M. Dennis, Frederik Deroose, Sandra Duffy, Sabine Fletcher, Guri Giaever, Irene Hallyburton, Francisco-Javier Gamo, Marinella Gebbia, R. Kiplin Guy, Zoe Hungerford, Kiaran Kirk, Maria J. Lafuente-Monasterio, Anna Lee, Stephan Meister, Corey Nislow, John P. Overington, George Papadatos, Luc Patiny, James Pham, Stuart A. Ralph, Andrea Ruecker, Eileen Ryan, Christopher Southan, Kumkum Srivastava, Chris Swain, Matthew J. Tarnowski, Patrick Thomson, Peter Turner, Iain M. Wallace, Timothy N. C. Wells, Karen White, Laura White, Paul Willis, Elizabeth A. Winzeler, Sergio Wittlin, Matthew H. Todd

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