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605 Systemically administered HER2-targeted ISACs provoke a rapid, local response that engages the innate and adaptive arms of the immune system to eradicate tumors in preclinical... by Marcin Kowanetz, Po Ho, Shelley Ackerman, Heidi LeBlanc, David Dornan, Michael Alonso, Cecelia Pearson, Andrew Luo, Richard Laura, Justin Kenkel, LIsa Blum, Angela Luo, Matthew Zhou, Joshua Gregorio, Brian Safina
Published 2020-11-01Article -
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784 BDC-2034: discovery of a CEA-targeting immune-stimulating antibody conjugate (ISAC) for solid tumors by Marcin Kowanetz, Shelley Ackerman, David Dornan, Michael Alonso, Edith Perez, Cecelia Pearson, Arthur Lee, Karla Henning, Steven Chapin, LIsa Blum, Angela Luo, Matthew Zhou, Brian Safina, Amreen Husain, William Mallet, Rishali Gadkari, Laughing Bear Torrez Dulgeroff, AAngela Luondrew Luo, Jennifer Melrose, Jess Nolin, Puneet Anand, Ganapathy Sarma, Liz Bogaert, Romas Kudirka, Yuyi Shen
Published 2021-11-01Article -
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1147-D Preclinical characterization of a novel claudin 18.2 targeting-ISAC with robust potency and acceptable safety profile by Matthew Zhou, William Mallet, Romas Kudirka, Han K Kim, Justin Monnier, Chi-Ling Fu, Jennifer E Melrose, Hung Dao, Paul D Ponath, Katelynn A McEachin, David T Omstead, Cindy Kreder, Stefan Chun, Ying Yueh Lee, Rachel Grgich, Tracey J Lin, Joshua A Walker, Karla A Henning, Shelley E Ackerman, Diane Carrera, Steven J Chapin, Dowdy Jackson, Changshou Gao, Michael N Alonso
Published 2023-11-01Article