Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis by Christopher Geven, Christopher Geven, Matthijs Kox, Matthijs Kox, Peter Pickkers, Peter Pickkers

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Precision Immunotherapy for Sepsis by Annemieke M. Peters van Ton, Matthijs Kox, Matthijs Kox, Wilson F. Abdo, Peter Pickkers, Peter Pickkers

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Commentary: Plasma angiotensin II is increased in critical coronavirus disease 2019 by Dirk van Lier, Matthijs Kox, Peter Pickkers

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Increased Plasma Levels of Danger-Associated Molecular Patterns Are Associated With Immune Suppression and Postoperative Infections in Patients Undergoing Cytoreductive Surgery and... by Guus P. Leijte, Guus P. Leijte, Hettie Custers, Jelle Gerretsen, Jelle Gerretsen, Amon Heijne, Johannes Roth, Thomas Vogl, Gert J. Scheffer, Peter Pickkers, Peter Pickkers, Matthijs Kox, Matthijs Kox

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The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study. by Jenneke Leentjens, Jessica Quintin, Jelle Gerretsen, Matthijs Kox, Peter Pickkers, Mihai G Netea

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Comparison of different lots of endotoxin and evaluation of potency over time in the experimental human endotoxemia model by Dorien Kiers, Guus P. Leijte, Jelle Gerretsen, Jelle Zwaag, Matthijs Kox, Peter Pickkers

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Endotoxemia-Induced Release of Pro-inflammatory Mediators Are Associated With Increased Glomerular Filtration Rate in Humans in vivo by Remi Beunders, Remi Beunders, Remi Beunders, Maren J. Schütz, Roger van Groenendael, Roger van Groenendael, Roger van Groenendael, Guus P. Leijte, Guus P. Leijte, Guus P. Leijte, Matthijs Kox, Matthijs Kox, Matthijs Kox, Lucas T. van Eijk, Lucas T. van Eijk, Lucas T. van Eijk, Peter Pickkers, Peter Pickkers, Peter Pickkers

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Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance by Aron Jansen, Niklas Bruse, Nicole Waalders, Jelle Gerretsen, Daniëlle Rijbroek, Peter Pickkers, Matthijs Kox

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CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo by Aron Jansen, Nicole J. B. Waalders, Dirk P. T. van Lier, Matthijs Kox, Peter Pickkers

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Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times? by Miranda van Berkel, Matthijs Kox, Tim Frenzel, Peter Pickkers, Jeroen Schouten, on behalf of the RCI-COVID-19 study group

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The chicken or the egg: low testosterone predisposes for COVID-19 or COVID-19 induces a decrease in testosterone? by Roeland F. Stolk, Henk J. van Leeuwen, Matthijs Kox, Marcel van Borren, Hans de Boer, Peter Pickkers

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Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes by Guus P. Leijte, Thomas Rimmelé, Matthijs Kox, Niklas Bruse, Céline Monard, Morgane Gossez, Guillaume Monneret, Peter Pickkers, Fabienne Venet

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No interplay between gut microbiota composition and the lipopolysaccharide‐induced innate immune response in humans in vivo by Quirine LM Habes, Prokopis Konstanti, Harmke D Kiers, Rebecca M Koch, Roeland F Stolk, Clara Belzer, Matthijs Kox, Peter Pickkers

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Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses by Jenneke Leentjens, Mark S. Gresnigt, Frank L. van de Veerdonk, Matthijs Kox, Bart Jan Kullberg, Peter Pickkers, Annemarie E. Brouwer, Mihai G. Netea

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Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity by Aline H. de Nooijer, Antigone Kotsaki, Eleftheria Kranidioti, Matthijs Kox, Peter Pickkers, Erik J. M. Toonen, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea

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COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients by Matthijs Kox, Tim Frenzel, Jeroen Schouten, Frank L. van de Veerdonk, Hans J. P. M. Koenen, Peter Pickkers, , on behalf of the RCI-COVID-19 study group

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Evidence‐based rationale for low dose nivolumab in critically ill patients with sepsis‐induced immunosuppression by Demy A. C. van denHaak, Leila‐Sophie Otten, Hans J. P. M. Koenen, Ruben L. Smeets, Berber Piet, Peter Pickkers, Matthijs Kox, Rob ter Heine

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Involvement of Lactate and Pyruvate in the Anti-Inflammatory Effects Exerted by Voluntary Activation of the Sympathetic Nervous System by Jelle Zwaag, Rob ter Horst, Ivana Blaženović, Daniel Stoessel, Jacqueline Ratter, Josephine M. Worseck, Nicolas Schauer, Rinke Stienstra, Mihai G. Netea, Dieter Jahn, Peter Pickkers, Matthijs Kox

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Systemic inflammation decreases pain threshold in humans in vivo. by Moniek de Goeij, Lucas T van Eijk, Pascal Vanelderen, Oliver H Wilder-Smith, Kris C Vissers, Johannes G van der Hoeven, Matthijs Kox, Gert Jan Scheffer, Peter Pickkers

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The influence of hypoxia on platelet function and plasmatic coagulation during systemic inflammation in humans in vivo by Dorien Kiers, Rahajeng N. Tunjungputri, Rowie Borkus, Gert-Jan Scheffer, Philip G. de groot, Rolf T. Urbanus, Andre J. van der ven, Peter Pickkers, Quirijn de Mast, Matthijs Kox

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