Impact of CYP2C9‐Interacting Drugs on Warfarin Pharmacogenomics by Saaket Agrawal, Meredith S. Heiss, Remington B. Fenter, Tatiana V. Abramova, Minoli A. Perera, Jennifer A. Pacheco, Maureen E. Smith, Laura J. Rasmussen‐Torvik, Alfred L. George Jr.

Get full text

Pathogenic and Uncertain Genetic Variants Have Clinical Cardiac Correlates in Diverse Biobank Participants by Tess D. Pottinger, Megan J. Puckelwartz, Lorenzo L. Pesce, Avery Robinson, Samuel Kearns, Jennifer A. Pacheco, Laura J. Rasmussen‐Torvik, Maureen E. Smith, Rex Chisholm, Elizabeth M. McNally

Get full text

Practitioners’ Confidence and Desires for Education in Cardiovascular and Sudden Cardiac Death Genetics by Laura Lopez Santibanez Jacome, Lisa M. Dellefave‐Castillo, Catherine A. Wicklund, Courtney L. Scherr, Debra Duquette, Gregory Webster, Maureen E. Smith, Kerstin Kalke, Adam S. Gordon, Kristen De Berg, Elizabeth M. McNally, Laura J. Rasmussen‐Torvik

Get full text

Defining the Critical Components of Informed Consent for Genetic Testing by Kelly E. Ormond, Maia J. Borensztein, Miranda L. G. Hallquist, Adam H. Buchanan, William Andrew Faucett, Holly L. Peay, Maureen E. Smith, Eric P. Tricou, Wendy R. Uhlmann, Karen E. Wain, Curtis R. Coughlin, On behalf of the Clinical Genome CADRe Workgroup

Get full text

Return of Genomic Results in the Genomic Medicine Projects of the eMERGE Network by Iftikhar J. Kullo, Ra'ad eHaddad, Cynthia A. Prows, Ingrid eHolm, Saskia C. Sanderson, Nanibaa' A. Garrison, Richard R. Sharp, Maureen E. Smith, Helena eKuivaniemi, Erwin P. Bottinger, John eConnolly, Brendan J. Keating, Catherine A. McCarty, Marc S. Williams, Gail P. Jarvik

Get full text

Genetic sex validation for sample tracking in next-generation sequencing clinical testing by Jianhong Hu, Viktoriya Korchina, Hana Zouk, Maegan V. Harden, David Murdock, Alyssa Macbeth, Steven M. Harrison, Niall Lennon, Christie Kovar, Adithya Balasubramanian, Lan Zhang, Gauthami Chandanavelli, Divya Pasham, Robb Rowley, Ken Wiley, Maureen E. Smith, Adam Gordon, Gail P. Jarvik, Patrick Sleiman, Melissa A. Kelly, Harris T. Bland, Mullai Murugan, Eric Venner, Eric Boerwinkle, the eMERGE III consortium, Cynthia Prows, Lisa Mahanta, Heidi L. Rehm, Richard A. Gibbs, Donna M. Muzny

Get full text

Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm. by Yoonjung Yoonie Joo, Jennifer A Pacheco, William K Thompson, Laura J Rasmussen-Torvik, Luke V Rasmussen, Frederick T J Lin, Mariza de Andrade, Kenneth M Borthwick, Erwin Bottinger, Andrew Cagan, David S Carrell, Joshua C Denny, Stephen B Ellis, Omri Gottesman, James G Linneman, Jyotishman Pathak, Peggy L Peissig, Ning Shang, Gerard Tromp, Annapoorani Veerappan, Maureen E Smith, Rex L Chisholm, Andrew J Gawron, M Geoffrey Hayes, Abel N Kho

Get full text

Conducting a large, multi-site survey about patients’ views on broad consent: challenges and solutions by Maureen E. Smith, Saskia C. Sanderson, Kyle B. Brothers, Melanie F. Myers, Jennifer McCormick, Sharon Aufox, Martha J. Shrubsole, Nanibaá A. Garrison, Nathaniel D. Mercaldo, Jonathan S. Schildcrout, Ellen Wright Clayton, Armand H. Matheny Antommaria, Melissa Basford, Murray Brilliant, John J. Connolly, Stephanie M. Fullerton, Carol R. Horowitz, Gail P. Jarvik, Dave Kaufman, Terri Kitchner, Rongling Li, Evette J. Ludman, Catherine McCarty, Valerie McManus, Sarah Stallings, Janet L. Williams, Ingrid A. Holm

Get full text

Ethical Considerations Related to Return of Results from Genomic Medicine Projects: The eMERGE Network (Phase III) Experience by Robyn Fossey, David Kochan, Erin Winkler, Joel E. Pacyna, Janet Olson, Stephen Thibodeau, John J. Connolly, Margaret Harr, Meckenzie A. Behr, Cynthia A. Prows, Beth Cobb, Melanie F. Myers, Nancy D. Leslie, Bahram Namjou-Khales, Hila Milo Rasouly, Julia Wynn, Alexander Fedotov, Wendy K. Chung, Ali Gharavi, Janet L. Williams, Lynn Pais, Ingrid Holm, Sharon Aufox, Maureen E. Smith, Aaron Scrol, Kathleen Leppig, Gail P. Jarvik, Georgia L. Wiesner, Rongling Li, Mary Stroud, Jordan W. Smoller, Richard R. Sharp, Iftikhar J. Kullo

Get full text

Understanding the Return of Genomic Sequencing Results Process: Content Review of Participant Summary Letters in the eMERGE Research Network by John A. Lynch, Richard R. Sharp, Sharon A. Aufox, Sarah T. Bland, Carrie Blout, Deborah J. Bowen, Adam H. Buchanan, Colin Halverson, Margaret Harr, Scott J. Hebbring, Nora Henrikson, Christin Hoell, Ingrid A. Holm, Gail Jarvik, Iftikhar J. Kullo, David C. Kochan, Eric B. Larson, Amanda Lazzeri, Kathleen A. Leppig, Jill Madden, Maddalena Marasa, Melanie F. Myers, Josh Peterson, Cynthia A. Prows, Alanna Kulchak Rahm, James Ralston, Hila Milo Rasouly, Aaron Scrol, Maureen E. Smith, Amy Sturm, Kelsey Stuttgen, Georgia Wiesner, Marc S. Williams, Julia Wynn, Janet L. Williams

Get full text

Returning Results in the Genomic Era: Initial Experiences of the eMERGE Network by Georgia L. Wiesner, Alanna Kulchak Rahm, Paul Appelbaum, Sharon Aufox, Sarah T. Bland, Carrie L. Blout, Kurt D. Christensen, Wendy K. Chung, Ellen Wright Clayton, Robert C. Green, Margaret H. Harr, Nora Henrikson, Christin Hoell, Ingrid A. Holm, Gail P. Jarvik, Iftikhar J. Kullo, Philip E. Lammers, Eric B. Larson, Noralane M. Lindor, Maddalena Marasa, Melanie F. Myers, Josh F. Peterson, Cynthia A. Prows, James D. Ralston, Hila Milo Rasouly, Richard R. Sharp, Maureen E. Smith, Sara L. Van Driest, Janet L. Williams, Marc S. Williams, Julia Wynn, Kathleen A. Leppig

Get full text

Genome-wide study of resistant hypertension identified from electronic health records. by Logan Dumitrescu, Marylyn D Ritchie, Joshua C Denny, Nihal M El Rouby, Caitrin W McDonough, Yuki Bradford, Andrea H Ramirez, Suzette J Bielinski, Melissa A Basford, High Seng Chai, Peggy Peissig, David Carrell, Jyotishman Pathak, Luke V Rasmussen, Xiaoming Wang, Jennifer A Pacheco, Abel N Kho, M Geoffrey Hayes, Martha Matsumoto, Maureen E Smith, Rongling Li, Rhonda M Cooper-DeHoff, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, David Carey, Catherine A McCarty, Marc S Williams, Dan M Roden, Erwin Bottinger, Julie A Johnson, Mariza de Andrade, Dana C Crawford

Get full text

Phenome Wide Association Studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index by Robert Michael Cronin, Julie R Field, Yuki eBradford, Christian M Shaffer, Robert J Carroll, Jonathan D Mosley, Lisa eBastarache, Todd L Edwards, Scott J Hebbring, Simon eLin, Lucia A Hindorff, Paul K Crane, Sarah ePendergrass, Marylyn D Ritchie, Dana C Crawford, Jyotishman ePathak, Suzette eBielinski, David S Carrell, David R Crosslin, David H Ledbetter, David J Carey, Gerard eTromp, Marc S Williams, Eric B Larson, Gail P Jarvik, Peggy L Peissig, Murray H Brilliant, Catherine Anne McCarty, Christopher G Chute, Iftikhar J Kullo, Erwin eBottinger, Rex eChisholm, Maureen E Smith, Dan M Roden, Joshua C Denny

Get full text

Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets by Kelsey M. Haas, Michael J. McGregor, Mehdi Bouhaddou, Benjamin J. Polacco, Eun-Young Kim, Thong T. Nguyen, Billy W. Newton, Matthew Urbanowski, Heejin Kim, Michael A. P. Williams, Veronica V. Rezelj, Alexandra Hardy, Andrea Fossati, Erica J. Stevenson, Ellie Sukerman, Tiffany Kim, Sudhir Penugonda, Elena Moreno, Hannes Braberg, Yuan Zhou, Giorgi Metreveli, Bhavya Harjai, Tia A. Tummino, James E. Melnyk, Margaret Soucheray, Jyoti Batra, Lars Pache, Laura Martin-Sancho, Jared Carlson-Stevermer, Alexander S. Jureka, Christopher F. Basler, Kevan M. Shokat, Brian K. Shoichet, Leah P. Shriver, Jeffrey R. Johnson, Megan L. Shaw, Sumit K. Chanda, Dan M. Roden, Tonia C. Carter, Leah C. Kottyan, Rex L. Chisholm, Jennifer A. Pacheco, Maureen E. Smith, Steven J. Schrodi, Randy A. Albrecht, Marco Vignuzzi, Lorena Zuliani-Alvarez, Danielle L. Swaney, Manon Eckhardt, Steven M. Wolinsky, Kris M. White, Judd F. Hultquist, Robyn M. Kaake, Adolfo García-Sastre, Nevan J. Krogan

Get full text