Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies by Carlos Benitéz‐Buelga, Thomas Helleday, Maurice Michel

Get full text

Inhibition of Glyoxalase-I Leads to Reduced Proliferation, Migration and Colony Formation, and Enhanced Susceptibility to Sorafenib in Hepatocellular Carcinoma by Maurice Michel, Marcus Hollenbach, Sabine Pohl, Cristina Ripoll, Alexander Zipprich

Get full text

Expression of glyoxalase-I is reduced in cirrhotic livers: A possible mechanism in the development of cirrhosis. by Marcus Hollenbach, Antje Thonig, Sabine Pohl, Cristina Ripoll, Maurice Michel, Alexander Zipprich

Get full text

Nonalcoholic Fatty Liver Disease Increases the Risk of Anxiety and Depression by Christian Labenz, Yvonne Huber, Maurice Michel, Michael Nagel, Peter R. Galle, Karel Kostev, Jörn M. Schattenberg

Get full text

Impairment of health-related quality of life among people with type 2 diabetes and advanced liver fibrosis by Maurice Michel, Jesús Funuyet-Salas, Michelle Doll, Saleh A. Alqahtani, Angelo Armandi, Christian Labenz, Peter R. Galle, Jörn M. Schattenberg

Get full text

Metabolic dysfunction-associated fatty liver disease in people living with HIV by Maurice Michel, Christian Labenz, Angelo Armandi, Leonard Kaps, Wolfgang Maximilian Kremer, Peter R. Galle, Daniel Grimm, Martin Sprinzl, Jörn M. Schattenberg

Get full text

Risk factors for poorer health literacy in patients with liver cirrhosis. by Leonard Kaps, Katharina Hildebrand, Michael Nagel, Maurice Michel, Wolfgang Maximilian Kremer, Max Hilscher, Peter R Galle, Jörn M Schattenberg, Marcus-Alexander Wörns, Christian Labenz

Get full text

Effect of hepatic steatosis and associated metabolic comorbidities on health‐related quality of life in people living with HIV by Maurice Michel, Christian Labenz, Malena Anders, Alisha Wahl, Lisann Girolstein, Leonard Kaps, Wolfgang M. Kremer, Yvonne Huber, Peter R. Galle, Martin Sprinzl, Jörn M. Schattenberg

Get full text

In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization by Maurice Michel, Evert J. Homan, Elisée Wiita, Kia Pedersen, Ingrid Almlöf, Anna-Lena Gustavsson, Thomas Lundbäck, Thomas Lundbäck, Thomas Helleday, Thomas Helleday, Ulrika Warpman Berglund

Get full text

Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis by Maurice Michel, Cornelius Hess, Leonard Kaps, Wolfgang M. Kremer, Max Hilscher, Peter R. Galle, Markus Moehler, Jörn M. Schattenberg, Marcus-Alexander Wörns, Christian Labenz, Michael Nagel

Get full text

Liver Frailty Index for Prediction of Short-Term Rehospitalization in Patients with Liver Cirrhosis by Leonard Kaps, Lejla Lukac, Maurice Michel, Wolfgang Maximilian Kremer, Max Hilscher, Simon Johannes Gairing, Peter R. Galle, Jörn M. Schattenberg, Marcus-Alexander Wörns, Michael Nagel, Christian Labenz

Get full text

Evaluation of IL‐6 for Stepwise Diagnosis of Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis by Simon Johannes Gairing, Julian Anders, Leonard Kaps, Michael Nagel, Maurice Michel, Wolfgang Maximilian Kremer, Max Hilscher, Peter Robert Galle, Jörn M. Schattenberg, Marcus‐Alexander Wörns, Christian Labenz

Get full text

Variability of transient elastography-based spleen stiffness performed at 100 Hz by Angelo Armandi, Talal Merizian, Merle Marie Werner, Harvey O. Coxson, Tiziana Sanavia, Giovanni Birolo, Isabella Gashaw, Judith Ertle, Maurice Michel, Peter R. Galle, Christian Labenz, Tilman Emrich, Jörn M. Schattenberg

Get full text

Inflammation in liver fibrosis and atrial fibrillation: A prospective population-based proteomic study by Joost Boeckmans, Maurice Michel, Alexander Gieswinkel, Oliver Tüscher, Stavros V. Konstantinides, Jochem König, Thomas Münzel, Karl J. Lackner, Jasmin Ghaemi Kerahrodi, Alexander K. Schuster, Philipp S. Wild, Peter R. Galle, Jörn M. Schattenberg

Get full text

Characteristics of bacterial infections and prevalence of multidrug-resistant bacteria in hospitalized patients with liver cirrhosis in Germany by Wolfgang Maximilian Kremer, Simon Johannes Gairing, Leonard Kaps, Esmeralda Ismail, Vasiliki Kalampoka, Max Hilscher, Maurice Michel, Ekkehard Siegel, Jörn M. Schattenberg, Peter R. Galle, Martin F. Sprinzl, Marcus-Alexander Wörns, Michael Nagel, Christian Labenz

Get full text

Computational and Experimental Druggability Assessment of Human DNA Glycosylases by Maurice Michel, Torkild Visnes, Evert J. Homan, Brinton Seashore-Ludlow, Mattias Hedenström, Elisée Wiita, Karl Vallin, Cynthia B. J. Paulin, Jiaxi Zhang, Olov Wallner, Martin Scobie, Andreas Schmidt, Annika Jenmalm-Jensen, Ulrika Warpman Berglund, Thomas Helleday

Get full text

Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects by Juan Miguel Baquero, Carlos Benítez-Buelga, Varshni Rajagopal, Zhao Zhenjun, Raúl Torres-Ruiz, Sarah Müller, Bishoy M. F. Hanna, Olga Loseva, Olov Wallner, Maurice Michel, Sandra Rodríguez-Perales, Helge Gad, Torkild Visnes, Thomas Helleday, Javier Benítez, Ana Osorio

Get full text

Outcomes in patients receiving palliative chemotherapy for advanced biliary tract cancer by Felix Thol, Simon Johannes Gairing, Carolin Czauderna, Thomas Thomaidis, Thomas Gamstätter, Yvonne Huber, Johanna Vollmar, Johanna Lorenz, Maurice Michel, Fabian Bartsch, Lukas Müller, Roman Kloeckner, Peter Robert Galle, Marcus-Alexander Wörns, Jens Uwe Marquardt, Markus Moehler, Arndt Weinmann, Friedrich Foerster

Get full text

Virtual fragment screening for DNA repair inhibitors in vast chemical space by Andreas Luttens, Duc Duy Vo, Emma R. Scaletti, Elisée Wiita, Ingrid Almlöf, Olov Wallner, Jonathan Davies, Sara Košenina, Liuzhen Meng, Maeve Long, Oliver Mortusewicz, Geoffrey Masuyer, Flavio Ballante, Maurice Michel, Evert Homan, Martin Scobie, Christina Kalderén, Ulrika Warpman Berglund, Andrii V. Tarnovskiy, Dmytro S. Radchenko, Yurii S. Moroz, Jan Kihlberg, Pål Stenmark, Thomas Helleday, Jens Carlsson

Get full text

Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

Get full text