Oncogenic alterations in advanced NSCLC: a molecular super-highway by Alex Friedlaender, Maurice Perol, Giuseppe Luigi Banna, Kaushal Parikh, Alfredo Addeo

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Response to the Combination of Osimertinib, Dabrafenib, and Trametinib in Leptomeningitis From EGFR-Mutant NSCLC With Acquired BRAF V600E Mutation: A Case Report by Orion Valet, Aurélie Swalduz, MD, Maxime Boussageon, MD, Adrien Buisson, Virginie Avrillon, MD, Bénédicte Mastroïanni, MD, Maurice Pérol, MD

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Implementing ctDNA Analysis in the Clinic: Challenges and Opportunities in Non-Small Cell Lung Cancer by Elisa Gobbini, Aurélie Swalduz, Matteo Giaj Levra, Sandra Ortiz-Cuaran, Anne-Claire Toffart, Maurice Pérol, Denis Moro-Sibilot, Pierre Saintigny

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Survival outcomes of patients with metastatic non-small cell lung cancer receiving chemotherapy or immunotherapy as first-line in a real-life setting by Yaniss Belaroussi, Fanny Bouteiller, Carine Bellera, David Pasquier, Maurice Perol, Didier Debieuvre, Thomas Filleron, Nicolas Girard, Roland Schott, Simone Mathoulin-Pélissier, Anne-Laure Martin, Sophie Cousin

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Radiomics combined with transcriptomics to predict response to immunotherapy from patients treated with PD-1/PD-L1 inhibitors for advanced NSCLC by Amine Bouhamama, Amine Bouhamama, Benjamin Leporq, Khuram Faraz, Jean-Philippe Foy, Maxime Boussageon, Maurice Pérol, Sandra Ortiz-Cuaran, François Ghiringhelli, Pierre Saintigny, Pierre Saintigny, Olivier Beuf, Frank Pilleul, Frank Pilleul

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Brigatinib for Pretreated, ALK-Positive, Advanced Non-Small-Cell Lung Cancers: Long-Term Follow-Up and Focus on Post-Brigatinib Lorlatinib Efficacy in the Multicenter, Real-World B... by Renaud Descourt, Maurice Pérol, Gaëlle Rousseau-Bussac, David Planchard, Bertrand Mennecier, Marie Wislez, Jacques Cadranel, Alexis Benjamin Cortot, Florian Guisier, Loïck Galland, Pascal Do, Roland Schott, Éric Dansin, Jennifer Arrondeau, Jean-Bernard Auliac, Margaux Geier, Christos Chouaïd

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Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based NGS assay. by Jordi Remon, Aurelie Swalduz, David Planchard, Sandra Ortiz-Cuaran, Laura Mezquita, Ludovic Lacroix, Cecile Jovelet, Etienne Rouleau, Camille Leonce, Frank De Kievit, Clive Morris, Greg Jones, Kelly Mercier, Karen Howarth, Emma Green, Maurice Pérol, Pierre Saintigny, Benjamin Besse

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Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer by Courèche-Guillaume Kaderbhai, Corentin Richard, Jean David Fumet, Anne Aarnink, Sandra Ortiz-Cuaran, Maurice Pérol, Pascal Foucher, Bruno Coudert, Laure Favier, Aurélie Lagrange, Emeric Limagne, Romain Boidot, Sylvain Ladoire, Michel Poudenx, Marius Ilie, Paul Hofman, Pierre Saintigny, François Ghiringhelli

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High Circulating Sonic Hedgehog Protein Is Associated With Poor Outcome in EGFR-Mutated Advanced NSCLC Treated With Tyrosine Kinase Inhibitors by Paul Takam Kamga, Aurélie Swalduz, Aurélie Swalduz, Adrien Costantini, Adrien Costantini, Catherine Julié, Catherine Julié, Jean-François Emile, Jean-François Emile, Maurice Pérol, Virginie Avrillon, Sandra Ortiz-Cuaran, Pierre de Saintigny, Pierre de Saintigny, Etienne Giroux-Leprieur, Etienne Giroux-Leprieur

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Real-life experience of ceritinib in crizotinib-pretreated ALK+ advanced non-small cell lung cancer patients by Jacques Cadranel, Alexis B. Cortot, Hervé Lena, Bertrand Mennecier, Pascal Do, Eric Dansin, Julien Mazieres, Christos Chouaid, Maurice Perol, Fabrice Barlesi, Gilles Robinet, Sylvie Friard, Luc Thiberville, Clarisse Audigier-Valette, Alain Vergnenegre, Virginie Westeel, Khemaies Slimane, Alexandru Buturuga, Denis Moro-Sibilot, Benjamin Besse

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Datasets for gene expression profiles of head and neck squamous cell carcinoma and lung cancer treated or not by PD1/PD-L1 inhibitors by Jean-Philippe Foy, Andy Karabajakian, Sandra Ortiz-Cuaran, Maxime Boussageon, Lucas Michon, Jebrane Bouaoud, Dorssafe Fekiri, Marie Robert, Kim-Arthur Baffert, Geneviève Hervé, Pauline Quilhot, Valéry Attignon, Angélique Girod, André Chaine, Mourad Benassarou, Philippe Zrounba, Christophe Caux, François Ghiringhelli, Sylvie Lantuejoul, Carole Crozes, Isabelle Brochériou, Maurice Pérol, Jérôme Fayette, Chloé Bertolus, Pierre Saintigny

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Effectiveness and safety of nivolumab in the treatment of lung cancer patients in France: preliminary results from the real-world EVIDENS study by Fabrice Barlesi, Adrien Dixmier, Didier Debieuvre, Christophe Raspaud, Jean-Bernard Auliac, Nicolas Benoit, Pierre Bombaron, Denis Moro-Sibilot, Clarisse Audigier-Valette, Bernard Asselain, Thomas Egenod, Audrey Rabeau, Jérôme Fayette, Myriam Locatelli Sanchez, Jean-Luc Labourey, Virginie Westeel, Pauline Lamoureux, François-Emery Cotte, Victoria Allan, Melinda Daumont, Juliette Dumanoir, Dorothée Reynaud, Christophe Yannick Calvet, Nicolas Ozan, Maurice Pérol

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460 Spatial distribution of infiltrating T lymphocytes with Immunoscore® CR T cells exhaustion test helps stratification of NSCLC patients treated with PD1/PDL1 inhibitors in the P... by Noémie Resseguier, Julien Mazières, Fabrice Barlesi, Maurice Pérol, Thomas Sbarrato, Fanny Arnoux, Stéphane Garcia, Jacques Fieschi-Meric, Vanina Leca, Alboukadel Kassambara, Lamia Ghezali, Pernelle Outters, Christelle Cotteaux-Lautard, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Luc Odier, Stéphane Hominal, Laurent Greillier

Survival of bronchopulmonary cancers according to radon exposure by Juliette Dessemon, Juliette Dessemon, Olivia Perol, Olivia Perol, Cécile Chauvel, Cécile Chauvel, Hugo Noelle, Hugo Noelle, Thomas Coudon, Thomas Coudon, Lény Grassot, Lény Grassot, Nicolas Foray, Elodie Belladame, Elodie Belladame, Jérôme Fayette, Françoise Fournie, Aurélie Swalduz, Eve-Marie Neidhart, Pierre Saintigny, Mayeul Tabutin, Maxime Boussageon, Frédéric Gomez, Virginie Avrillon, Maurice Perol, Barbara Charbotel, Barbara Charbotel, Béatrice Fervers, Béatrice Fervers

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782-C Regulatory T-cell tumor infiltration is associated to better outcome in advanced NSCLC patients under ≥2nd line anti-PD1/L1 monotherapy in the PIONeeR project by Lilian Laborde, Julien Mazières, Fabrice Barlesi, Jacques Fieschi, Maurice Pérol, Vanina Leca, Alboukadel Kassambara, Florence Monville, Maryannick Le Ray, Marie Roumieux, Richard Malkoun, Arnaud Boyer, Louisiane Lebas, Hervé Pegliasco, Patricia Barré, Clarisse Audigier-valette, Sarah Zahi, Stéphane Hominal, Laurent Greillier, Marcellin Landri, Margot Vasseur, Chafik Hamdad, Margaux Mercadal, Laurent Vanhille, Sebastien Benzekry, Stephanie Martinez, Patrice Ray, Lionel Falchero, Antoine Serre, Nicolas Cloarec, Ahmed Frikha, Pierre Bory