One size does not fit all: Lysosomes exist in biochemically and functionally distinct states. by Claudio Bussi, Maximiliano G Gutierrez

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High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages by Beren Aylan, Laure Botella, Maximiliano G. Gutierrez, Pierre Santucci

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Rab GTPases in Immunity and Inflammation by Akriti Prashar, Laura Schnettger, Elliott M. Bernard, Maximiliano G. Gutierrez

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Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs. by Antony Fearns, Daniel J Greenwood, Angela Rodgers, Haibo Jiang, Maximiliano G Gutierrez

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Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide by Pierre Santucci, Daniel J. Greenwood, Antony Fearns, Kai Chen, Haibo Jiang, Maximiliano G. Gutierrez

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Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells by Thomas R. Lerner, Christophe J. Queval, Antony Fearns, Urska Repnik, Gareth Griffiths, Maximiliano G. Gutierrez

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Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis by Pierre Santucci, Beren Aylan, Laure Botella, Elliott M. Bernard, Claudio Bussi, Enrica Pellegrino, Natalia Athanasiadi, Maximiliano G. Gutierrez

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Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes by Dimitrios Evangelopoulos, Gareth A. Prosser, Angela Rodgers, Belinda M. Dagg, Bhagwati Khatri, Mei Mei Ho, Maximiliano G. Gutierrez, Teresa Cortes, Luiz Pedro S. de Carvalho

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Rv2617c and P36 are virulence factors of pathogenic mycobacteria involved in resistance to oxidative stress by Marina A. Forrellad, Cristina L. Vázquez, Federico C. Blanco, Laura I. Klepp, Elizabeth A. García, Rosana V. Rocha, Villafañe Luciana, María M. Bigi, Maximiliano G. Gutierrez, Fabiana Bigi

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The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection by Alexandre Giraud-Gatineau, Juan Manuel Coya, Alexandra Maure, Anne Biton, Michael Thomson, Elliott M Bernard, Jade Marrec, Maximiliano G Gutierrez, Gérald Larrouy-Maumus, Roland Brosch, Brigitte Gicquel, Ludovic Tailleux

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ER-dependent membrane repair of mycobacteria-induced vacuole damage by Aby Anand, Anna-Carina Mazur, Patricia Rosell-Arevalo, Rico Franzkoch, Leonhard Breitsprecher, Stevanus A. Listian, Sylvana V. Hüttel, Danica Müller, Deise G. Schäfer, Simone Vormittag, Hubert Hilbi, Markus Maniak, Maximiliano G. Gutierrez, Caroline Barisch

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Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation. by Christophe J Queval, Antony Fearns, Laure Botella, Alicia Smyth, Laura Schnettger, Morgane Mitermite, Esen Wooff, Bernardo Villarreal-Ramos, Waldo Garcia-Jimenez, Tiaan Heunis, Matthias Trost, Dirk Werling, Francisco J Salguero, Stephen V Gordon, Maximiliano G Gutierrez

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Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism by Claudio Bussi, Tiaan Heunis, Enrica Pellegrino, Elliott M. Bernard, Nourdine Bah, Mariana Silva Dos Santos, Pierre Santucci, Beren Aylan, Angela Rodgers, Antony Fearns, Julia Mitschke, Christopher Moore, James I. MacRae, Maria Greco, Thomas Reinheckel, Matthias Trost, Maximiliano G. Gutierrez

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miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity. by Marcin Łyszkiewicz, Samantha J Winter, Katrin Witzlau, Lisa Föhse, Rebecca Brownlie, Jacek Puchałka, Nikita A Verheyden, Heike Kunze-Schumacher, Esther Imelmann, Jonas Blume, Solaiman Raha, Takashi Sekiya, Akihiko Yoshimura, Jochen T Frueh, Evelyn Ullrich, Jochen Huehn, Siegfried Weiss, Maximiliano G Gutierrez, Immo Prinz, Rose Zamoyska, Natalia Ziętara, Andreas Krueger

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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages by Melissa Bedard, Sanne van der Niet, Elliott M. Bernard, Gregory Babunovic, Tan-Yun Cheng, Beren Aylan, Anita E. Grootemaat, Sahadevan Raman, Laure Botella, Eri Ishikawa, Mary P. O’Sullivan, Seónadh O’Leary, Jacob A. Mayfield, Jeffrey Buter, Adriaan J. Minnaard, Sarah M. Fortune, Leon O. Murphy, Daniel S. Ory, Joseph Keane, Sho Yamasaki, Maximiliano G. Gutierrez, Nicole van der Wel, D. Branch Moody

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