Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib. by Watson, A, Sabharwal, A, Thorncroft, M, McGown, G, Kerr, R, Bojanic, S, Soonawalla, Z, King, A, Miller, A, Waller, S, Leung, H, Margison, G, Middleton, MR

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours. by Khan, O, Gore, M, Lorigan, P, Stone, J, Greystoke, A, Burke, W, Carmichael, J, Watson, A, McGown, G, Thorncroft, M, Margison, G, Califano, R, Larkin, J, Wellman, S, Middleton, MR

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours by Khan, O, Gore, M, Lorigan, P, Stone, J, Greystoke, A, Burke, W, Carmichael, J, Watson, A, McGown, G, Thorncroft, M, Margison, G, Califano, R, Larkin, J, Wellman, S, Middleton, M

Temozolomide pharmacodynamics in patients with metastatic melanoma: dna damage and activity of repair enzymes O6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1. by Plummer, E, Middleton, M, Jones, C, Olsen, A, Hickson, I, McHugh, P, Margison, G, McGown, G, Thorncroft, M, Watson, A, Boddy, A, Calvert, A, Harris, A, Newell, DR, Curtin, N

O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib. by Watson, A, Middleton, MR, McGown, G, Thorncroft, M, Ranson, M, Hersey, P, McArthur, G, Davis, I, Thomson, D, Beith, J, Haydon, A, Kefford, R, Lorigan, P, Mortimer, P, Sabharwal, A, Hayward, O, Margison, G