XPF-ERCC1: Linchpin of DNA crosslink repair by McHugh, PJ

The SNM1A DNA repair nuclease by Baddock, HT, Yosaatmadja, Y, Newman, JA, Schofield, CJ, Gileadi, O, McHugh, PJ

A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family by Baddock, HT, Newman, JA, Yosaatmadja, Y, Bielinski, M, Schofield, CJ, Gileadi, O, McHugh, PJ

PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation by Ronson, G, Piberger, A, Higgs, MR, Olsen, AL, Stewart, G, McHugh, PJ, Petermann, E, Lakin, ND

N-Acyloxymethyl-phthalimides deliver genotoxic formaldehyde to human cells by Emms, VL, Lewis, LA, Beja, L, Bulman, NFA, Pires, E, Muskett, FW, Mccullagh, JSO, Swift, LP, McHugh, PJ, Hopkinson, RJ

Structural and mechanistic insights into the Artemis endonuclease and strategies for its inhibition by Yosaatmadja, Y, Baddock, HT, Newman, JA, Bielinski, M, Gavard, AE, Mukhopadhyay, SMM, Dannerfjord, AA, Schofield, CJ, McHugh, PJ, Gileadi, O

Characterization of the SARS-CoV-2 ExoN (nsp14ExoN–nsp10) complex: implications for its role in viral genome stability and inhibitor identification by Baddock, HT, Brolih, S, Yosaatmadja, Y, Ratnaweera, M, Bielinski, M, Swift, LP, Cruz-Migoni, A, Fan, H, Keown, JR, Walker, AP, Morris, GM, Grimes, JM, Fodor, E, Schofield, CJ, Gileadi, O, McHugh, PJ

Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target by Bielinski, M, Henderson, LR, Yosaatmadja, Y, Swift, LP, Baddock, HT, Bowen, MJ, Brem, J, Jones, PS, McElroy, SP, Morrison, A, Speake, M, van Boeckel, S, van Doornmalen, E, van Groningen, J, van den Hurk, H, Gileadi, O, Newman, JA, McHugh, PJ, Schofield, CJ

Neuronal enhancers are hotspots for DNA single-strand break repair by Wu, W, Hill, SE, Nathan, WJ, Paiano, J, Callen, E, Wang, D, Shinoda, K, van Wietmarschen, N, Colón-Mercado, JM, Zong, D, De Pace, R, Shih, H-Y, Coon, S, Parsadanian, M, Pavani, R, Hanzlikova, H, Park, S, Jung, SK, McHugh, PJ, Canela, A, Chen, C, Casellas, R, Caldecott, KW, Ward, ME, Nussenzweig, A

Antiviral activity of bone morphogenetic proteins and activins by Eddowes, LA, Al-Hourani, K, Ramamurthy, N, Frankish, J, Baddock, HT, Sandor, C, Ryan, JD, Fusco, DN, Arezes, J, Giannoulatou, E, Boninsegna, S, Chevaliez, S, Owens, BMJ, Sun, CC, Fabris, P, Giordani, MT, Martines, D, Vukicevic, S, Crowe, J, Lin, HY, Rehwinkel, J, McHugh, PJ, Binder, M, Babitt, JL, Chung, RT, Lawless, MW, Armitage, AE, Webber, C, Klenerman, P, Drakesmith, H

Genetic and functional insights into CDA-I prevalence and pathogenesis by Olijnik, A-A, Scott, C, Roy, NB, Marsh, JA, Brown, J, Laushke, K, Ask, K, Roberts, N, Downes, DJ, Brolih, S, Johnson, E, Xella, B, Proven, M, Hipkiss, R, Ryan, K, Frisk, P, Johan, M, Stattin, E-LM, Sadasivam, N, McIlwaine, L, Hill, QA, Renella, R, Hughes, JR, Gibbons, RJ, Groth, A, McHugh, PJ, Higgs, DR, Buckle, VJ, Babbs, C

Repeat expansions confer WRN dependence in microsatellite-unstable cancers by van Wietmarschen, N, Sridharan, S, Nathan, WJ, Tubbs, A, Chan, EM, Callen, E, Wu, W, Belinky, F, Tripathi, V, Wong, N, Foster, K, Noorbakhsh, J, Garimella, K, Cruz-Migoni, A, Sommers, JA, Huang, Y, Borah, AA, Smith, JT, Kalfon, J, Kesten, N, Fugger, K, Walker, RL, Dolzhenko, E, Eberle, MA, Hayward, BE, Usdin, K, Freudenreich, CH, Brosh, RM, West, SC, McHugh, PJ, Meltzer, PS, Bass, AJ, Nussenzweig, A