Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci. Por Niittymäki, I, Tuupanen, S, Li, Y, Järvinen, H, Mecklin, J, Tomlinson, I, Houlston, R, Karhu, A, Aaltonen, L

Proportion and phenotype of MYH-associated colorectal neoplasia in a population-based series of Finnish colorectal cancer patients. Por Enholm, S, Hienonen, T, Suomalainen, A, Lipton, L, Tomlinson, I, Kärjä, V, Eskelinen, M, Mecklin, J, Karhu, A, Järvinen, H, Aaltonen, L

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis Por Kokko, A, Laiho, P, Lehtonen, R, Korja, S, Carvajal-Carmona, L, Järvinen, H, Mecklin, J, Eng, C, Schleutker, J, Tomlinson, I, Vahteristo, P, Aaltonen, L

LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome. Por Volikos, E, Robinson, J, Aittomäki, K, Mecklin, J, Järvinen, H, Westerman, A, de Rooji, F, Vogel, T, Moeslein, G, Launonen, V, Tomlinson, I, Silver, A, Aaltonen, L

Mutations in Exon 1 Highlight the Role of MED12 in Uterine Leiomyomas Por Kämpjärvi, K, Park, M, Mehine, M, Kim, N, Clark, A, Bützow, R, Böhling, T, Böhm, J, Mecklin, J, Järvinen, H, Tomlinson, I, van der Spuy, Z, Sjöberg, J, Boyer, T, Vahteristo, P

Mutations in exon 1 highlight the role of MED12 in uterine leiomyomas Por Kämpjärvi, K, Park, M, Mehine, M, Kim, N, Clark, A, Bützow, R, Böhling, T, Böhm, J, Mecklin, J, Järvinen, H, Tomlinson, I, van der Spuy, Z, Sjöberg, J, Boyer, T, Vahteristo, P

Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases. Por Laiho, P, Hienonen, T, Karhu, A, Lipton, L, Aalto, Y, Thomas, H, Birkenkamp-Demtroder, K, Hodgson, S, Salovaara, R, Mecklin, J, Järvinen, H, Knuutila, S, Halford, S, Ørntoft, T, Tomlinson, I, Launonen, V, Houlston, R, Aaltonen, L

The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population. Por Rasinperä, H, Forsblom, C, Enattah, N, Halonen, P, Salo, K, Victorzon, M, Mecklin, J, Järvinen, H, Enholm, S, Sellick, G, Alazzouzi, H, Houlston, R, Robinson, J, Groop, P, Tomlinson, I, Schwartz, S, Aaltonen, L, Järvelä, I

The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Por Tuupanen, S, Turunen, M, Lehtonen, R, Hallikas, O, Vanharanta, S, Kivioja, T, Björklund, M, Wei, G, Yan, J, Niittymäki, I, Mecklin, J, Järvinen, H, Ristimäki, A, Di-Bernardo, M, East, P, Carvajal-Carmona, L, Houlston, R, Tomlinson, I, Palin, K, Ukkonen, E, Karhu, A, Taipale, J, Aaltonen, L

Unregulated smooth-muscle myosin in human intestinal neoplasia. Por Alhopuro, P, Phichith, D, Tuupanen, S, Sammalkorpi, H, Nybondas, M, Saharinen, J, Robinson, J, Yang, Z, Chen, L, Orntoft, T, Mecklin, J, Järvinen, H, Eng, C, Moeslein, G, Shibata, D, Houlston, R, Lucassen, A, Tomlinson, I, Launonen, V, Ristimäki, A, Arango, D, Karhu, A, Sweeney, H, Aaltonen, L

Germline mutations in BMPR1A/ALK3 cause a subset of cases of Juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes Por Zhou, X, Woodford-Richens, K, Lehtonen, R, Kurose, K, Aldred, M, Hampel, H, Launonen, V, Virta, S, Pilarski, R, Salovaara, R, Bodmer, W, Conrad, B, Dunlop, M, Hodgson, S, Iwama, T, Järvinen, H, Kellokumpu, I, Kim, J, Leggett, B, Markie, D, Mecklin, J, Neale, K, Phillips, R, Piris, J, Rozen, P

Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes. Por Zhou, X, Woodford-Richens, K, Lehtonen, R, Kurose, K, Aldred, M, Hampel, H, Launonen, V, Virta, S, Pilarski, R, Salovaara, R, Bodmer, W, Conrad, B, Dunlop, M, Hodgson, S, Iwama, T, Järvinen, H, Kellokumpu, I, Kim, J, Leggett, B, Markie, D, Mecklin, J, Neale, K, Phillips, R, Piris, J, Rozen, P

Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Por Mathers, J, Movahedi, M, Macrae, F, Mecklin, J, Moeslein, G, Olschwang, S, Eccles, D, Evans, G, Maher, E, Bertario, L, Bisgaard, M, Dunlop, M, Ho, J, Hodgson, S, Lindblom, A, Lubinski, J, Morrison, P, Murday, V, Ramesar, R, Side, L, Scott, R, Thomas, H, Vasen, H, Gerdes, A, Barker, G

Association analyses identify 31 new risk loci for colorectal cancer susceptibility Por Law, PJ, Timofeeva, M, Fernandez-Rozadilla, C, Broderick, P, Studd, J, Fernandez-Tajes, J, Farrington, S, Svinti, V, Palles, C, Orlando, G, Sud, A, Holroyd, A, Penegar, S, Theodoratou, E, Vaughan-Shaw, P, Campbell, H, Zgaga, L, Hayward, C, Campbell, A, Harris, S, Deary, IJ, Starr, J, Gatcombe, L, Pinna, M, Briggs, S, Martin, L, Jaeger, E, Sharma-Oates, A, East, J, Leedham, S, Arnold, R, Johnstone, E, Wang, H, Kerr, D, Kerr, R, Maughan, T, Kaplan, R, Al-Tassan, N, Palin, K, Hänninen, UA, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A-P, Eriksson, JG, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, J-P, Buchanan, DD, Win, A-K, Hopper, J, Jenkins, ME, Lindor, NM, Newcomb, PA, Gallinger, S, Duggan, D, Casey, G, Hoffmann, P, Nöthen, MM, Jöckel, K-H, Easton, DF, Pharoah, PDP, Peto, J, Canzian, F, Swerdlow, A, Eeles, RA, Kote-Jarai, Z, Muir, K, Pashayan, N, Practical Consortium, Harkin, A, Allan, K, McQueen, J, Paul, J, Iveson, T, Saunders, M, Butterbach, K, Chang-Claude, J, Hoffmeister, M, Brenner, H, Kirac, I, Matošević, P, Hofer, P, Brezina, S, Gsur, A, Cheadle, JP, Aaltonen, LA, Tomlinson, I, Houlston, RS, Dunlop, MG