Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins... by Nadja M. Pieper, Julia Schnell, Daniela Bruecher, Stefan Knapp, Meike Vogler

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DLBCL Cells with Acquired Resistance to Venetoclax Are Not Sensitized to BIRD-2 But Can Be Resensitized to Venetoclax through Bcl-XL Inhibition by Martijn Kerkhofs, Tamara Vervloessem, Kinga B. Stopa, Victoria M. Smith, Meike Vogler, Geert Bultynck

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Characterization of BV6-Induced Sensitization to the NK Cell Killing of Pediatric Rhabdomyosarcoma Spheroids by Vinzenz Särchen, Lisa Marie Reindl, Sara Wiedemann, Senthan Shanmugalingam, Thomas Bukur, Julia Becker, Martin Suchan, Evelyn Ullrich, Meike Vogler

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Computational modeling of DLBCL predicts response to BH3-mimetics by Ielyaas Cloete, Victoria M. Smith, Ross A. Jackson, Andrea Pepper, Chris Pepper, Meike Vogler, Martin J. S. Dyer, Simon Mitchell

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Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies by Aoula Al-Zebeeby, Meike Vogler, Mateus Milani, Caitlin Richards, Ahoud Alotibi, Georgia Greaves, Martin J.S. Dyer, Gerald M. Cohen, Shankar Varadarajan

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Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells by Maria Baou, Susan L. Kohlhaas, Michael Butterworth, Meike Vogler, David Dinsdale, Renata Walewska, Aneela Majid, Eric Eldering, Martin J.S. Dyer, Gerald M. Cohen

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Specific interactions of BCL-2 family proteins mediate sensitivity to BH3-mimetics in diffuse large B-cell lymphoma by Victoria M. Smith, Anna Dietz, Kristina Henz, Daniela Bruecher, Ross Jackson, Lisa Kowald, Sjoerd J.L. van Wijk, Sandrine Jayne, Salvador Macip, Simone Fulda, Martin J.S. Dyer, Meike Vogler

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Identification of a novel form of caspase-independent cell death triggered by BH3-mimetics in diffuse large B-cell lymphoma cell lines by Nahide Yildirim, Lakshmi Sarojam, Victoria M. Smith, Nadja M. Pieper, Marius Anders, Ross A. Jackson, Dominik C. Fuhrmann, Vinzenz Särchen, Daniela Brücher, Andreas Weigert, Martin J. S. Dyer, Meike Vogler

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CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma by Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Laura M. Moser, Catrin Heim, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Sebastian E. Koschade, Philipp Wendel, Philipp Wendel, Philipp Wendel, Philipp Wendel, Süleyman Bozkurt, Sabine Harenkamp, Hermann Kreyenberg, Hermann Kreyenberg, Michael Merker, Michael Merker, Christian Münch, Christian Münch, Christian Münch, Elise Gradhand, Meike Vogler, Meike Vogler, Meike Vogler, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Halvard Bönig, Halvard Bönig, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Jan-Henning Klusmann, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Peter Bader, Winfried S. Wels, Winfried S. Wels, Winfried S. Wels, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger, Eva Rettinger

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P1354: CRISPR/CAS9 GENE EDITING OF IMMUNE CHECKPOINT RECEPTOR NKG2A IMPROVES THE ANTI-LEUKEMIC EFFICACY OF PRIMARY CD33-TARGETING CAR-NK CELLS. by Nawid Albinger, Tobias Bexte, Ahmad Al-Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Raj Bhayadia, Jan-Henning Klusmann, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich

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Pediatric multicellular tumor spheroid models illustrate a therapeutic potential by combining BH3 mimetics with Natural Killer (NK) cell-based immunotherapy by Vinzenz Särchen, Senthan Shanmugalingam, Sarah Kehr, Lisa Marie Reindl, Victoria Greze, Sara Wiedemann, Cathinka Boedicker, Maureen Jacob, Katrin Bankov, Nina Becker, Sibylle Wehner, Till M. Theilen, Steffen Gretser, Elise Gradhand, Carsten Kummerow, Evelyn Ullrich, Meike Vogler

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CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells by Tobias Bexte, Nawid Albinger, Ahmad Al Ajami, Philipp Wendel, Leon Buchinger, Alec Gessner, Jamal Alzubi, Vinzenz Särchen, Meike Vogler, Hadeer Mohamed Rasheed, Beate Anahita Jung, Sebastian Wolf, Raj Bhayadia, Thomas Oellerich, Jan-Henning Klusmann, Olaf Penack, Nina Möker, Toni Cathomen, Michael A. Rieger, Katharina Imkeller, Evelyn Ullrich

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