Asciminib Maintains Antibody-Dependent Cellular Cytotoxicity against Leukemic Blasts by Samuel J. Holzmayer, Joseph Kauer, Jonas Mauermann, Tobias Roider, Melanie Märklin

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Expression of the immune checkpoint modulator OX40 indicates poor survival in acute myeloid leukemia by Maddalena Marconato, Joseph Kauer, Helmut R. Salih, Melanie Märklin, Jonas S. Heitmann

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DNAM-1/CD226 is functionally expressed on acute myeloid leukemia (AML) cells and is associated with favorable prognosis by Anna Chashchina, Melanie Märklin, Clemens Hinterleitner, Helmut R. Salih, Jonas S. Heitmann, Boris Klimovich

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B7-H3-targeting Fc-optimized antibody for induction of NK cell reactivity against sarcoma by Ilona Hagelstein, Ilona Hagelstein, Monika Engel, Monika Engel, Clemens Hinterleitner, Clemens Hinterleitner, Timo Manz, Melanie Märklin, Melanie Märklin, Gundram Jung, Gundram Jung, Helmut R. Salih, Helmut R. Salih, Latifa Zekri, Latifa Zekri, Latifa Zekri

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965 NFAT2 drives the cytoskeletal remodeling of leukemia cells, which regulates their vulnerability to perforin-mediated killing by Melanie Märklin, Jonas S Heitmann, Helmut R Salih, Samuel Holzmayer, Jonas Mauermann, Sarah Maria Greiner, Kuebra Kaban

Therapeutic Silencing of BCL-2 Using NK Cell-Derived Exosomes as a Novel Therapeutic Approach in Breast Cancer by Kübra Kaban, Clemens Hinterleitner, Yanjun Zhou, Emine Salva, Ayse Gülten Kantarci, Helmut R. Salih, Melanie Märklin

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1365 An immunocytokine with target cell-restricted IL-15 activity for induction of anti-tumor immunity against acute myeloid leukemia by Melanie Märklin, Gundram Jung, Martin Pflügler, Helmut R Salih, Latifa Zekri, Martina S Lutz, Bastian Schmied, Fabian Riegg

1390 A Fc-optimized B7-H3 antibody for induction of NK cell reactivity against acute myeloid leukemia by Melanie Märklin, Ilona Hagelstein, Jonas S Heitmann, Helmut R Salih, Latifa Zekri, Martina S Lutz, Sylwia A Stefanczyk, Stefanie Müller

CD18 Antibody Application Blocks Unwanted Off-Target T Cell Activation Caused by Bispecific Antibodies by Joseph Kauer, Fabian Vogt, Ilona Hagelstein, Sebastian Hörner, Melanie Märklin, Stefanie Maurer, Helmut R. Salih, Gundram Jung, Latifa Zekri

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An Fc-Optimized CD133 Antibody for Induction of NK Cell Reactivity against B Cell Acute Lymphoblastic Leukemia by Fabian Riegg, Martina S. Lutz, Bastian J. Schmied, Jonas S. Heitmann, Manon Queudeville, Peter Lang, Gundram Jung, Helmut R. Salih, Melanie Märklin

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Immunoprofiling of 4-1BB Expression Predicts Outcome in Chronic Lymphocytic Leukemia (CLL) by Kübra Kaban, Sarah M. Greiner, Samuel Holzmayer, Claudia Tandler, Sophie Meyer, Clemens Hinterleitner, Helmut R. Salih, Melanie Märklin, Jonas S. Heitmann

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Bispecific NKG2D-CD3 and NKG2D-CD16 fusion proteins for induction of NK and T cell reactivity against acute myeloid leukemia by Melanie Märklin, Ilona Hagelstein, Samuel P. Koerner, Kathrin Rothfelder, Martin S. Pfluegler, Andreas Schumacher, Ludger Grosse-Hovest, Gundram Jung, Helmut R. Salih

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Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody by Sylwia A. Stefańczyk, Ilona Hagelstein, Martina S. Lutz, Stefanie Müller, Samuel J. Holzmayer, Grace Jarjour, Latifa Zekri, Jonas S. Heitmann, Helmut R. Salih, Melanie Märklin

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Platelet-mediated shedding of NKG2D ligands impairs NK cell immune-surveillance of tumor cells by Stefanie Maurer, Korbinian Nepomuk Kropp, Gerd Klein, Alexander Steinle, Sebastian P. Haen, Juliane S. Walz, Clemens Hinterleitner, Melanie Märklin, Hans-Georg Kopp, Helmut Rainer Salih

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Bispecific NKG2D-CD3 and NKG2D-CD16 Fusion Proteins as Novel Treatment Option in Advanced Soft Tissue Sarcomas by Ilona Hagelstein, Ilona Hagelstein, Martina S. Lutz, Martina S. Lutz, Moritz Schmidt, Moritz Schmidt, Moritz Schmidt, Jonas S. Heitmann, Jonas S. Heitmann, Elke Malenke, Yanjun Zhou, Yanjun Zhou, Kim L. Clar, Kim L. Clar, Hans-Georg Kopp, Hans-Georg Kopp, Gundram Jung, Gundram Jung, Helmut R. Salih, Helmut R. Salih, Melanie Märklin, Melanie Märklin, Clemens Hinterleitner, Clemens Hinterleitner

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Targeting NKG2DL with Bispecific NKG2D–CD16 and NKG2D–CD3 Fusion Proteins on Triple–Negative Breast Cancer by Polina Kaidun, Samuel J. Holzmayer, Sarah M. Greiner, Anna Seller, Christian M. Tegeler, Ilona Hagelstein, Jonas Mauermann, Tobias Engler, André Koch, Andreas D. Hartkopf, Helmut R. Salih, Melanie Märklin

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Soluble NKG2DLs Are Elevated in Breast Cancer Patients and Associate with Disease Outcome by Anna Seller, Christian M. Tegeler, Jonas Mauermann, Tatjana Schreiber, Ilona Hagelstein, Kai Liebel, André Koch, Jonas S. Heitmann, Sarah M. Greiner, Clara Hayn, Dominik Dannehl, Tobias Engler, Andreas D. Hartkopf, Markus Hahn, Sara Y. Brucker, Helmut R. Salih, Melanie Märklin

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PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity by Anita Schmitt, Brigitte Neuber, Michael Schmitt, Melanie Märklin, Boris Klimovich, Claudia Lengerke, Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Daniela Chmiest, Silvia Podavini, Fulya Korkmaz, Corina Schneidawind, Dominik Schneidawind

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A novel IgG-based FLT3xCD3 bispecific antibody for the treatment of AML and B-ALL by Melanie Märklin, Gundram Jung, Jonas S Heitmann, Joseph Kauer, Helmut R Salih, Stefanie Mueller, Bochong Li, Latifa Zekri, Naveen K Mehta, Martin Pfluegler, Kristan Meetze, Isabelle Sindel, Fabian Vogt, Lukas Osburg, Hans-Jörg Bühring, Sebastian Hörner, Patrick A Baeuerle, Jennifer S Michaelson

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Phase I study evaluating the Fc-optimized FLT3 antibody FLYSYN in AML patients with measurable residual disease by Jonas S. Heitmann, Richard F. Schlenk, Daniela Dörfel, Sabine Kayser, Konstanze Döhner, Michael Heuser, Felicitas Thol, Silke Kapp-Schwoerer, Jannik Labrenz, Dominic Edelmann, Melanie Märklin, Wichard Vogel, Wolfgang Bethge, Juliane S. Walz, Ludger Große-Hovest, Martin Steiner, Gundram Jung, Helmut R. Salih

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