Editorial: Epigenetic Regulation of Innate Immunity by Menno P. J. de Winther, Tanapat Palaga

Get full text

Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites by Koen F. Dekkers, Annette E. Neele, J. Wouter Jukema, Bastiaan T. Heijmans, Menno P. J. de Winther

Get full text

Absence of p55 TNF receptor reduces atherosclerosis, but has no major effect on angiotensin II induced aneurysms in LDL receptor deficient mice. by Sofia Xanthoulea, Melanie Thelen, Chantal Pöttgens, Marion J J Gijbels, Esther Lutgens, Menno P J de Winther

Get full text

Meta-Analysis of in vitro-Differentiated Macrophages Identifies Transcriptomic Signatures That Classify Disease Macrophages in vivo by Hung-Jen Chen, Andrew Y. F. Li Yim, Andrew Y. F. Li Yim, Guillermo R. Griffith, Wouter J. de Jonge, Marcel M. A. M. Mannens, Enrico Ferrero, Peter Henneman, Menno P. J. de Winther, Menno P. J. de Winther

Get full text

Selective Targeting of Epigenetic Readers and Histone Deacetylases in Autoimmune and Inflammatory Diseases: Recent Advances and Future Perspectives by Mohammed Ghiboub, Ahmed M. I. Elfiky, Menno P. J. de Winther, Nicola R. Harker, David F. Tough, Wouter J. de Jonge

Get full text

An insect homolog of the vertebrate very low density lipoprotein receptor mediates endocytosis of lipophorins by Nico P. Dantuma, Marc Potters, Menno P.J. De Winther, Cornelis P. Tensen, Frank P. Kooiman, Jan Bogerd, Dick J. Van der Horst

Get full text

The Epigenetic Reader Protein SP140 Regulates Dendritic Cell Activation, Maturation and Tolerogenic Potential by Mohammed Ghiboub, Matthew Bell, Dovile Sinkeviciute, Rab K. Prinjha, Menno P. J. de Winther, Nicola R. Harker, David F. Tough, Wouter J. de Jonge

Get full text

Local delivery of polarized macrophages improves reperfusion recovery in a mouse hind limb ischemia model. by Nadine Jetten, Marjo M P C Donners, Allard Wagenaar, Jack P M Cleutjens, Nico van Rooijen, Menno P J de Winther, Mark J Post

Get full text

Myeloid-Specific Acly Deletion Alters Macrophage Phenotype <i>In Vitro</i> and <i>In Vivo</i> without Affecting Tumor Growth by Kyra E. de Goede, Sanne G. S. Verberk, Jeroen Baardman, Karl J. Harber, Yvette van Kooyk, Menno P. J. de Winther, Sjoerd T. T. Schetters, Jan Van den Bossche

Get full text

Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction. by Suzanne A B M Aarts, Myrthe E Reiche, Myrthe den Toom, Linda Beckers, Marion J J Gijbels, Norbert Gerdes, Menno P J de Winther, Esther Lutgens

Get full text

Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis by Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J.J. Gijbels, Marion J.J. Gijbels, Cindy P.P.A. van Roomen, Sharon G. Bernard, Wouter J. de Jonge, Inmaculada Rioja, Rab K. Prinjha, Huw D. Lewis, Palwinder K. Mander, Menno P.J. de Winther, Menno P.J. de Winther

Get full text

Succinate Is an Inflammation-Induced Immunoregulatory Metabolite in Macrophages by Karl J. Harber, Kyra E. de Goede, Sanne G. S. Verberk, Elisa Meinster, Helga E. de Vries, Michel van Weeghel, Menno P. J. de Winther, Jan Van den Bossche

Get full text

HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages by Mohammed Ghiboub, Mohammed Ghiboub, Jing Zhao, Andrew Y. F. Li Yim, Andrew Y. F. Li Yim, Ronald Schilderink, Caroline Verseijden, Patricia H. P. van Hamersveld, Jose M. Duarte, Theodorus B. M. Hakvoort, Iris Admiraal, Nicola R. Harker, David F. Tough, Peter Henneman, Menno P. J. de Winther, Menno P. J. de Winther, Wouter J. de Jonge, Wouter J. de Jonge

Get full text

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice by Kikkie Poels, Mandy M. T. van Leent, Myrthe E. Reiche, Pascal J. H. Kusters, Stephan Huveneers, Menno P. J. de Winther, Willem J. M. Mulder, Esther Lutgens, Tom T. P. Seijkens

Get full text

T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation by Winnie G. Vos, Winnie G. Vos, Winnie G. Vos, Bram W. van Os, Bram W. van Os, Bram W. van Os, Myrthe den Toom, Linda Beckers, Cindy P.A.A. van Roomen, Claudia M. van Tiel, Bhopal C. Mohapatra, Hamid Band, Katrin Nitz, Katrin Nitz, Katrin Nitz, Christian Weber, Christian Weber, Christian Weber, Christian Weber, Dorothee Atzler, Dorothee Atzler, Dorothee Atzler, Menno P.J. de Winther, Menno P.J. de Winther, Menno P.J. de Winther, Laura A. Bosmans, Laura A. Bosmans, Laura A. Bosmans, Esther Lutgens, Esther Lutgens, Esther Lutgens, Tom T.P. Seijkens, Tom T.P. Seijkens, Tom T.P. Seijkens

Get full text

Hematopoietic miR155 deficiency enhances atherosclerosis and decreases plaque stability in hyperlipidemic mice. by Marjo M P C Donners, Ine M J Wolfs, Lauran J Stöger, Emiel P C van der Vorst, Chantal C H Pöttgens, Stephane Heymans, Blanche Schroen, Marion J J Gijbels, Menno P J de Winther

Get full text

Pharmacological validation of targets regulating CD14 during macrophage differentiation by Gisela Jimenez-Duran, Rosario Luque-Martin, Meghana Patel, Emma Koppe, Sharon Bernard, Catriona Sharp, Natalie Buchan, Ceara Rea, Menno P.J. de Winther, Nil Turan, Davina Angell, Christine A. Wells, Rick Cousins, Palwinder K. Mander, Seth L. Masters

Get full text

Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques. by Pieter Goossens, Monique N Vergouwe, Marion J J Gijbels, Danielle M J Curfs, Johannes H G van Woezik, Marten A Hoeksema, Sofia Xanthoulea, Pieter J M Leenen, Rudolf A Rupec, Marten H Hofker, Menno P J de Winther

Get full text

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice. by Pathricia V Tilstam, Marion J Gijbels, Mohamed Habbeddine, Céline Cudejko, Yaw Asare, Wendy Theelen, Baixue Zhou, Yvonne Döring, Maik Drechsler, Lukas Pawig, Sakine Simsekyilmaz, Rory R Koenen, Menno P J de Winther, Toby Lawrence, Jürgen Bernhagen, Alma Zernecke, Christian Weber, Heidi Noels

Get full text

Arginase-1 deficiency regulates arginine concentrations and NOS2-mediated NO production during endotoxemia. by Karolina A P Wijnands, Marten A Hoeksema, Dennis M Meesters, Nynke M S van den Akker, Daniel G M Molin, Jacob J Briedé, Mitrajit Ghosh, S Eleonore Köhler, Marc A M J van Zandvoort, Menno P J de Winther, Wim A Buurman, Wouter H Lamers, Martijn Poeze

Get full text