Variants close to NTRK2 gene are associated with birth weight in female twins by Metrustry, S, Edwards, M, Medland, SE, Holloway, J, Montgomery, G, Martin, N, Spector, T, Cooper, C, Valdes, A

Variants close to NTRK2 gene are associated with birth weight in female twins. by Metrustry, S, Edwards, M, Medland, SE, Holloway, J, Montgomery, G, Martin, N, Spector, T, Cooper, C, Valdes, A

Molecular pathways associated with blood pressure and hexadecanedioate levels. by Cristina Menni, Sarah J Metrustry, Georg Ehret, Anna F Dominiczak, Phil Chowienczyk, Tim D Spector, Sandosh Padmanabhan, Ana M Valdes

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Prediction model for knee osteoarthritis incidence, including clinical, genetic and biochemical risk factors. by Kerkhof, H, Bierma-Zeinstra, S, Arden, N, Metrustry, S, Castano-Betancourt, M, Hart, D, Hofman, A, Rivadeneira, F, Oei, E, Spector, T, Uitterlinden, A, Janssens, A, Valdes, A, van Meurs, J

Metabolomic signatures of low birthweight: Pathways to insulin resistance and oxidative stress. by Sarah Jane Metrustry, Ville Karhunen, Mark H Edwards, Cristina Menni, Thomas Geisendorfer, Anja Huber, Christian Reichel, Elaine M Dennison, Cyrus Cooper, Tim Spector, Marjo-Riitta Jarvelin, Ana M Valdes

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META-ANALYSIS IDENTIFIES NOVEL GENES INFLUENCING LEVELS OF THE POTENTIAL OA BIOMARKERS SCOMP AND UCTX2 by Ramos, Y, van Meurs, J, Valdes, A, Metrustry, S, Hart, D, Arden, N, Kloppenburg, M, Lafeber, F, van Spil, E, Karsdal, M, Bay-Jensen, A, Spector, T, Uitterlinden, A, Slagboom, P, Meulenbelt, I

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a Mendelian randomisation study. by Panoutsopoulou, K, Metrustry, S, Doherty, SA, Laslett, L, Maciewicz, R, Hart, D, Zhang, W, Muir, K, Wheeler, M, Cooper, C, Spector, T, Cicuttini, F, Jones, G, Arden, N, Doherty, M, Zeggini, E, Valdes, A

A GENOME WIDE ASSOCIATION STUDY ON JOINT SPACE WIDTH IDENTIFIES A NEW GENE INVOLVED IN CARTILAGE THICKNESS AND OSTEOARTHRITIS by Betancourt, M, Valdes, A, Cornelis, F, Kerkhof, H, Doherty, S, Wheeler, M, Zhang, W, Maciewicz, R, Muir, K, Hart, D, Metrustry, S, Mangino, M, Arden, N, Cailotto, F, Peters, M, Rivadeneira, F, Hofman, A, Uitterlinden, A, Doherty, M, Spector, T, Lories, R, van Meurs, J

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. by Betancourt, C, Cailotto, F, Kerkhof, H, Cornelis, F, Doherty, SA, Hart, D, Hofman, A, Luyten, F, Maciewicz, R, Mangino, M, Metrustry, S, Muir, K, Peters, M, Rivadeneira, F, Wheeler, M, Zhang, W, Arden, N, Spector, T, Uitterlinden, A, Doherty, M, Lories, R, Valdes, A, van Meurs, J

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. by Styrkarsdottir, U, Thorleifsson, G, Helgadottir, H, Bomer, N, Metrustry, S, Bierma-Zeinstra, S, Strijbosch, A, Evangelou, E, Hart, D, Beekman, M, Jonasdottir, A, Sigurdsson, A, Eiriksson, F, Thorsteinsdottir, M, Frigge, M, Kong, A, Gudjonsson, SA, Magnusson, O, Masson, G, Hofman, A, Arden, N, Ingvarsson, T, Lohmander, S, Kloppenburg, M, Rivadeneira, F

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. by Valdes, A, Styrkarsdottir, U, Doherty, M, Morris, D, Mangino, M, Tamm, A, Doherty, SA, Kisand, K, Kerna, I, Tamm, A, Wheeler, M, Maciewicz, R, Zhang, W, Muir, K, Dennison, E, Hart, D, Metrustry, S, Jonsdottir, I, Jonsson, G, Jonsson, H, Ingvarsson, T, Cooper, C, Vyse, T, Spector, T, Stefansson, K, Arden, N

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. by Evangelou, E, Kerkhof, H, Styrkarsdottir, U, Ntzani, E, Bos, S, Esko, T, Evans, D, Metrustry, S, Panoutsopoulou, K, Ramos, Y, Thorleifsson, G, Tsilidis, K, Arden, N, Aslam, N, Bellamy, N, Birrell, F, Blanco, F, Carr, A, Chapman, K, Day-Williams, A, Deloukas, P, Doherty, M, Engström, G, Helgadottir, H, Hofman, A

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-ii with genome wide significance by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. by Ana M Valdes, Unnur Styrkarsdottir, Michael Doherty, David L Morris, Massimo Mangino, Agu Tamm, Sally A Doherty, Kalle Kisand, Irina Kerna, Ann Tamm, Margaret Wheeler, Rose A Maciewicz, Weiya Zhang, Kenneth R Muir, Elaine M Dennison, Deborah J Hart, Sarah Metrustry, Ingileif Jonsdottir, Gudbjorn F Jonsson, Helgi Jonsson, Thorvaldur Ingvarsson, Cyrus Cooper, Timothy J Vyse, Tim D Spector, Kari Stefansson, Nigel K Arden

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Novel genetic variants for cartilage thickness and hip osteoarthritis by Castaño-Betancourt, MC, Evans, DS, Ramos, YF, Boer, CG, Metrustry, S, Liu, Y, Hollander, W, van Rooij, J, Kraus, VB, Yau, MS, Mitchell, BD, Muir, K, Hofman, A, Doherty, M, Doherty, S, Zhang, W, Kraaij, R, Rivadeneira, F, Barrett-Connor, E, Maciewicz, RA, Arden, N, Nelissen, RG, Kloppenburg, M, Jordan, JM, Nevitt, MC, Slagboom, EP, Hart, DJ, Lafeber, F, Styrkarsdottir, U, Zeggini, E, Evangelou, E, Spector, TD, Uitterlinden, AG, Lane, NE, Meulenbelt, I, Valdes, AM, van Meurs, JB

Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis. by Martha C Castaño-Betancourt, Dan S Evans, Yolande F M Ramos, Cindy G Boer, Sarah Metrustry, Youfang Liu, Wouter den Hollander, Jeroen van Rooij, Virginia B Kraus, Michelle S Yau, Braxton D Mitchell, Kenneth Muir, Albert Hofman, Michael Doherty, Sally Doherty, Weiya Zhang, Robert Kraaij, Fernando Rivadeneira, Elizabeth Barrett-Connor, Rose A Maciewicz, Nigel Arden, Rob G H H Nelissen, Margreet Kloppenburg, Joanne M Jordan, Michael C Nevitt, Eline P Slagboom, Deborah J Hart, Floris Lafeber, Unnur Styrkarsdottir, Eleftheria Zeggini, Evangelos Evangelou, Tim D Spector, Andre G Uitterlinden, Nancy E Lane, Ingrid Meulenbelt, Ana M Valdes, Joyce B J van Meurs

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. by Zeggini, E, Panoutsopoulou, K, Southam, L, Rayner, N, Day-Williams, A, Lopes, M, Boraska, V, Esko, T, Evangelou, E, Hoffman, A, Houwing-Duistermaat, J, Ingvarsson, T, Jonsdottir, I, Jonnson, H, Kerkhof, H, Kloppenburg, M, Bos, S, Mangino, M, Metrustry, S, Slagboom, P, Thorleifsson, G, Raine, E, Ratnayake, M, Ricketts, M, Beazley, C, Blackburn, H, Bumpstead, S, Elliott, K, Hunt, SE, Potter, S, Shin, S, Yadav, V, Zhai, G, Sherburn, K, Dixon, K, Arden, E, Aslam, N, Battley, P, Carluke, I, Doherty, S, Gordon, A, Joseph, J, Keen, R, Koller, N, Mitchell, S, O'Neill, F, Paling, E, Reed, MR, Rivadeneira, F, Swift, D, Walker, K, Watkins, B, Wheeler, M, Birrell, F, Ioannidis, J, Meulenbelt, I, Metspalu, A, Rai, A, Salter, D, Stefansson, K, Stykarsdottir, U, Uitterlinden, A, van Meurs, J, Chapman, K, Deloukas, P, Ollier, W, Wallis, G, Arden, N, Carr, A, Doherty, M, McCaskie, A, Willkinson, J, Ralston, S, Valdes, A, Spector, T, Loughlin, J

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. by Beaumont, RN, Warrington, NM, Cavadino, A, Tyrrell, J, Nodzenski, M, Horikoshi, M, Geller, F, Myhre, R, Richmond, RC, Paternoster, L, Bradfield, JP, Kreiner-Møller, E, Huikari, V, Metrustry, S, Lunetta, KL, Painter, JN, Hottenga, J-J, Allard, C, Barton, SJ, Espinosa, A, Marsh, JA, Potter, C, Zhang, G, Ang, W, Berry, DJ, Bouchard, L, Das, S, Hakonarson, H, Heikkinen, J, Helgeland, Ø, Hocher, B, Hofman, A, Inskip, HM, Jones, SE, Kogevinas, M, Lind, PA, Marullo, L, Medland, SE, Murray, A, Murray, JC, Njølstad, PR, Nohr, EA, Reichetzeder, C, Ring, SM, Ruth, KS, Santa-Marina, L, Scholtens, DM, Sebert, S, Sengpiel, V, Tuke, MA, Vaudel, M, Weedon, MN, Willemsen, G, Wood, AR, Yaghootkar, H, Muglia, LJ, Bartels, M, Relton, CL, Pennell, CE, Chatzi, L, Estivill, X, Holloway, JW, Boomsma, DI, Montgomery, GW, Murabito, JM, Spector, TD, Power, C, Järvelin, M-R, Bisgaard, H, Grant, SF, Sørensen, TI, Jaddoe, VW, Jacobsson, B, Melbye, M, McCarthy, MI, Hattersley, AT, Hayes, MG, Frayling, TM, Hivert, M-F, Felix, JF, Hyppönen, E, Lowe, WL, Evans, DM, Lawlor, DA, Feenstra, B, Freathy, RM