Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells by Kasela, S, Kisand, K, Tserel, L, Kaleviste, E, Remm, A, Fischer, K, Esko, T, Westra, H, Fairfax, B, Makino, S, Knight, J, Franke, L, Metspalu, A, Peterson, P, Milani, L

Hidden heritability due to heterogeneity across seven populations. by Tropf, FC, Lee, SH, Verweij, RM, Stulp, G, van der Most, PJ, de Vlaming, R, Bakshi, A, Briley, DA, Rahal, C, Hellpap, R, Nyman, A, Esko, T, Metspalu, A, Medland, SE, Martin, NG, Barban, N, Snieder, H, Robinson, MR, Mills, MC

Hidden heritability due to heterogeneity across seven populations by Tropf, FC, Lee, SH, Verweij, RM, Stulp, G, van der Moost, PJ, de Vlaming, R, Bakshi, A, Briley, DA, Rahal, C, Hellpap, R, Nyman, A, Esko, T, Metspalu, A, Medland, SE, Martin, NG, Barban, N, Snieder, H, Robinson, MR, Mills, MC

Genetic variants linked to education predict longevity by Marioni, R, Ritchie, S, Joshi, P, Hagenaars, S, Okbay, A, Fischer, K, Adams, M, Hill, W, Davies, G, Social Science Genetic Association Consortium, Nagy, R, Amador, C, Läll, K, Metspalu, A, Liewald, D, Campbell, A, Wilson, J, Hayward, C, Esko, T, Porteous, D, Gale, C, Deary, I

COMMON VARIANTS IN SKELETAL DYSPLASIA GENES ARE ASSOCIATED WITH OSTEOARTHRITIS by Kerkhof, H, Panagiotou, O, Irving, M, Esko, T, Meulenbelt, I, Panoutsopoulou, K, Styrkarsdottir, U, Zhu, Y, Cupples, A, Felson, D, Kloppenburg, M, Arden, N, Albert, H, Slagboom, E, Frank, L, Metspalu, A, Ioannidis, J, Jonsdottir, I, Stefansson, K, Spector, T, Uitterlinden, A, Zeggini, E, Valdes, A, Evangelou, V, van Meurs, J

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo. by Andaloussi, SE, Lehto, T, Mäger, I, Rosenthal-Aizman, K, Oprea, I, Simonson, O, Sork, H, Ezzat, K, Copolovici, D, Kurrikoff, K, Viola, JR, Zaghloul, E, Sillard, R, Johansson, H, Said Hassane, F, Guterstam, P, Suhorutšenko, J, Moreno, P, Oskolkov, N, Hälldin, J, Tedebark, U, Metspalu, A, Lebleu, B, Lehtiö, J, Smith, C

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-ii with genome wide significance by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Evidence for genetic overlap between schizophrenia and age at first birth in women by Tropf, F, Mills, M, Barban, N, Mehta, D, Gratten, J, Bakshi, A, Zhu, Z, Bacanu, S, Hermani, G, Magnusson, P, Esko, T, Metspalu, A, Snieder, H, Mowry, B, Kendler, K, Yang, J, Visscher, P, McGrath, J, Wray, N, Lee, S, Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, TwinsUK

Toward a roadmap in global biobanking for health by Harris, JR, Burton, P, Knoppers, B, Lindpaintner, K, Bledsoe, M, Brookes, A, Budin-Ljosne, I, Chisholm, R, Cox, D, Deschênes, M, Fortier, I, Hainaut, P, Hewitt, R, Kaye, J, Litton, J, Metspalu, A, Ollier, B, Palmer, L, Palotie, A, Pasterk, M, Perola, M, Riegman, P, Van Ommen, G, Yuille, M, Zatloukal, K

Toward a roadmap in global biobanking for health. by Harris, JR, Burton, P, Knoppers, B, Lindpaintner, K, Bledsoe, M, Brookes, A, Budin-Ljøsne, I, Chisholm, R, Cox, D, Deschênes, M, Fortier, I, Hainaut, P, Hewitt, R, Kaye, J, Litton, J, Metspalu, A, Ollier, B, Palmer, L, Palotie, A, Pasterk, M, Perola, M, Riegman, P, van Ommen, G, Yuille, M, Zatloukal, K

Genome-wide study identifies association between HLA-B∗55:01 and self-reported penicillin allergy by Krebs, K, Bovijn, J, Zheng, N, Lepamets, M, Censin, JC, Jürgenson, T, Särg, D, Abner, E, Laisk, T, Luo, Y, Skotte, L, Geller, F, Feenstra, B, Wang, W, Auton, A, 23andMe Research Team, Raychaudhuri, S, Esko, T, Metspalu, A, Laur, S, Roden, DM, Wei, W-Q, Holmes, MV, Lindgren, CM, Phillips, EJ, Mägi, R, Milani, L, Fadista, J

Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions by Shungin, D, Deng, W, Varga, T, Luan, J, Mihailov, E, Metspalu, A, GIANT Consortium, Morris, A, Forouhi, N, Lindgren, C, Magnusson, P, Pedersen, N, Hallmans, G, Chu, A, Justice, A, Graff, M, Winkler, T, Rose, L, Langenberg, C, Cupples, L, Ridker, P, Wareham, N, Ong, K, Loos, R, Chasman, D, Ingelsson, E, Kilpeläinen, T, Scott, R, Mägi, R, Paré, G, Franks, P

Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity by Walters, R, Coin, L, Ruokonen, A, De Smith, A, El-Sayed Moustafa, J, Jacquemont, S, Elliott, P, Esko, T, Hartikainen, A, Laitinen, J, Männik, K, Martinet, D, Meyre, D, Nauck, M, Schurmann, C, Sladek, R, Thorleifsson, G, Thorsteinsdóttir, U, Valsesia, A, Waeber, G, Zufferey, F, Balkau, B, Pattou, F, Metspalu, A, Völzke, H, Vollenweider, P, Stefansson, K, Järvelin, MR, Beckmann, J, Froguel, P, Blakemore, A

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response by Luo, Y, Kanai, M, Choi, W, Li, X, Sakaue, S, Yamamoto, K, Ogawa, K, Gutierrez-Arcelus, M, Gregersen, PK, Stuart, PE, Elder, JT, Forer, L, Schönherr, S, Fuchsberger, C, Smith, AV, Fellay, J, Carrington, M, Haas, DW, Guo, X, Palmer, ND, Chen, Y-DI, Rotter, JI, Taylor, KD, Rich, SS, Correa, A, Wilson, JG, Kathiresan, S, Cho, MH, Metspalu, A, Esko, T, Okada, Y, Han, B, McLaren, PJ, Raychaudhuri, S

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci by Ellinghaus, D, Jostins, L, Spain, S, Cortes, A, Bethune, J, Han, B, Park, Y, Raychaudhuri, S, Pouget, J, Hübenthal, M, Folseraas, T, Wang, Y, Esko, T, Metspalu, A, Westra, H, Franke, L, Pers, T, Weersma, R, Collij, V, D'Amato, M, Halfvarson, J, Jensen, A, Lieb, W, Degenhardt, F, Forstner, A, Hofmann, A, Schreiber, S, Mrowietz, U, Juran, B, Lazaridis, K, Brunak, S, Dale, A, Trembath, R, Weidinger, S, Weichenthal, M, Ellinghaus, E, Elder, J, Barker, J, Andreassen, O, McGovern, D, Karlsen, T, Barrett, J, Parkes, M, Brown, M, Franke, A

Genetic predisposition to coronary artery disease in type 2 diabetes by van Zuydam, NR, Ladenvall, C, Voight, BF, Strawbridge, RJ, Fernandez Tajes, J, Rayner, NW, Robertson, NR, Mahajan, A, Vlachopoulou, E, Goel, A, Kleber, ME, Nelson, CP, Kwee, LC, Esko, T, Mihailov, E, Mägi, R, Milani, L, Fischer, K, Kanoni, S, Kumar, J, Song, C, Hartiala, JA, Pedersen, NL, Perola, M, Gieger, C, Peters, A, Qu, L, Willems, SM, Doney, ASF, Morris, AD, Zheng, Y, Sesti, G, Hu, FB, Qi, L, Laakso, M, Thorsteinsdottir, U, Grallert, H, van Duijn, C, Reilly, MP, Ingelsson, E, Deloukas, P, Kathiresan, S, Metspalu, A, Shah, SH, Sinisalo, J, Salomaa, V, Hamsten, A, Samani, NJ, März, W, Hazen, SL, Watkins, H

Distribution and medical impact of loss-of-function variants in the Finnish founder population by Lim, E, Würtz, P, Havulinna, A, Palta, P, Tukiainen, T, Rehnström, K, Esko, T, Mägi, R, Inouye, M, Lappalainen, T, Chan, Y, Salem, R, Lek, M, Flannick, J, Sim, X, Manning, A, Ladenvall, C, Bumpstead, S, Hämäläinen, E, Aalto, K, Maksimow, M, Salmi, M, Blankenberg, S, Ardissino, D, Shah, S, Horne, B, McPherson, R, Hovingh, G, Reilly, M, Watkins, H, Goel, A, Farrall, M, Girelli, D, Reiner, A, Stitziel, N, Kathiresan, S, Gabriel, S, Barrett, J, Lehtimäki, T, Laakso, M, Groop, L, Kaprio, J, Perola, M, McCarthy, M, Boehnke, M, Altshuler, D, Lindgren, C, Hirschhorn, J, Metspalu, A, Freimer, N, Zeller, T, Jalkanen, S, Koskinen, S, Raitakari, O, Durbin, R, Macarthur, D, Salomaa, V, Ripatti, S, Daly, M, Palotie, A

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci by Tanskanen, T, van den Berg, L, Välimäki, N, Aavikko, M, Ness-Jensen, E, Hveem, K, Wettergren, Y, Lindskog, E, Tõnisson, N, Metspalu, A, Silander, K, Orlando, G, Law, PJ, Tuupanen, S, Gylfe, AE, Hänninen, UA, Cajuso, T, Kondelin, J, Sarin, AP, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Mecklin, JP, Al-Tassan, NA, Palles, C, Martin, L, Barclay, E, Tenesa, A, Farrington, SM, Timofeeva, MN, Meyer, BF, Wakil, SM, Campbell, H, Smith, CG, Idziaszczyk, S, Maughan, TS, Kaplan, R, Kerr, R, Kerr, D, Buchanan, DD, Win, AK, Hopper, J, Jenkins, MA, Newcomb, PA, Gallinger, S, Conti, D, Schumacher, FR, Casey, G, Cheadle, JP, Dunlop, MG, Tomlinson, IP, Houlston, RS, Palin, K, Aaltonen, LA

Association analyses based on false discovery rate implicate new loci for coronary artery disease by Nelson, CP, Goel, A, Butterworth, AS, Kanoni, S, Webb, TR, Marouli, E, Zeng, L, Ntalla, I, Lai, FY, Hopewell, JC, Giannakopoulou, O, Jiang, T, Hamby, SE, Di Angelantonio, E, Assimes, TL, Bottinger, EP, Chambers, JC, Clarke, R, Palmer, CNA, Cubbon, RM, Ellinor, P, Ermel, R, Evangelou, E, Franks, PW, Grace, C, Gu, D, Hingorani, AD, Howson, JMM, Ingelsson, E, Kastrati, A, Kessler, T, Kyriakou, T, Lehtimäki, T, Lu, X, Lu, Y, März, W, McPherson, R, Metspalu, A, Pujades-Rodriguez, M, Ruusalepp, A, Schadt, EE, Schmidt, AF, Sweeting, MJ, Zalloua, PA, AlGhalayini, K, Keavney, BD, Kooner, JS, Loos, RJF, Patel, RS, Rutter, MK, Tomaszewski, M, Tzoulaki, I, Zeggini, E, Erdmann, J, Dedoussis, G, Björkegren, JLM, EPIC-CVD Consortium, CARDIoGRAMplusC4D, UK Biobank CardioMetabolic Consortium CHD working group, Schunkert, H, Farrall, M, Danesh, J, Samani, NJ, Watkins, H, Deloukas, P