Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation by Tatyana Bodrug, Kaeli A. Welsh, Megan Hinkle, Michael J. Emanuele, Nicholas G. Brown

Get full text

A proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cells by Tony Ly, Yasmeen Ahmad, Adam Shlien, Dominique Soroka, Allie Mills, Michael J Emanuele, Michael R Stratton, Angus I Lamond

Get full text

AtomNet-Aided OTUD7B Inhibitor Discovery and Validation by Jianfeng Chen, Derek L. Bolhuis, Christian Laggner, Deyu Kong, Le Yu, Xiaodong Wang, Michael J. Emanuele, Nicholas G. Brown, Pengda Liu

Get full text

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2 by Taylor P Enrico, Wayne Stallaert, Elizaveta T Wick, Peter Ngoi, Xianxi Wang, Seth M Rubin, Nicholas G Brown, Jeremy E Purvis, Michael J Emanuele

Get full text

The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery by Rajarshi Choudhury, Thomas Bonacci, Xianxi Wang, Andrew Truong, Anthony Arceci, Yanqiong Zhang, Christine A. Mills, Jennifer L. Kernan, Pengda Liu, Michael J. Emanuele

Get full text

APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry by Rajarshi Choudhury, Thomas Bonacci, Anthony Arceci, Debojyoti Lahiri, Christine A. Mills, Jennifer L. Kernan, Timothy B. Branigan, James A. DeCaprio, Daniel J. Burke, Michael J. Emanuele

Get full text

APC/C and SCFcyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry by Rajarshi Choudhury, Thomas Bonacci, Anthony Arceci, Debojyoti Lahiri, Christine A. Mills, Jennifer L. Kernan, Timothy B. Branigan, James A. DeCaprio, Daniel J. Burke, Michael J. Emanuele

Get full text

Inhibition of CDK1 by RO-3306 Exhibits Anti-Tumorigenic Effects in Ovarian Cancer Cells and a Transgenic Mouse Model of Ovarian Cancer by Yu Huang, Yali Fan, Ziyi Zhao, Xin Zhang, Katherine Tucker, Allison Staley, Hongyan Suo, Wenchuan Sun, Xiaochang Shen, Boer Deng, Stuart R. Pierce, Lindsay West, Yajie Yin, Michael J. Emanuele, Chunxiao Zhou, Victoria Bae-Jump

Get full text

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators. by Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, Michael J Emanuele

Get full text

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins by Xiuxiu Lu, Monika Chandravanshi, Venkata R. Sabbasani, Snehal Gaikwad, V. Keith Hughitt, Nana Gyabaah-Kessie, Bradley T. Scroggins, Sudipto Das, Wazo Myint, Michelle E. Clapp, Charles D. Schwieters, Marzena A. Dyba, Derek L. Bolhuis, Janusz W. Koscielniak, Thorkell Andresson, Michael J. Emanuele, Nicholas G. Brown, Hiroshi Matsuo, Raj Chari, Deborah E. Citrin, Beverly A. Mock, Rolf E. Swenson, Kylie J. Walters

Get full text